TopFIND 4.0

Q8IUZ5: 5-phosphohydroxy-L-lysine phospho-lyase

General Information

Protein names
- 5-phosphohydroxy-L-lysine phospho-lyase
- 4.2.3.134
- Alanine--glyoxylate aminotransferase 2-like 2
Gene names PHYKPL
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IUZ5

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAADQRPKAD TLALRQRLIS SSCRLFFPED PVKIVRAQGQ YMYDEQGAEY IDCISNVAHV 
        70         80         90        100        110        120 
GHCHPLVVQA AHEQNQVLNT NSRYLHDNIV DYAQRLSETL PEQLCVFYFL NSGSEANDLA 
       130        140        150        160        170        180 
LRLARHYTGH QDVVVLDHAY HGHLSSLIDI SPYKFRNLDG QKEWVHVAPL PDTYRGPYRE 
       190        200        210        220        230        240 
DHPNPAMAYA NEVKRVVSSA QEKGRKIAAF FAESLPSVGG QIIPPAGYFS QVAEHIRKAG 
       250        260        270        280        290        300 
GVFVADEIQV GFGRVGKHFW AFQLQGKDFV PDIVTMGKSI GNGHPVACVA ATQPVARAFE 
       310        320        330        340        350        360 
ATGVEYFNTF GGSPVSCAVG LAVLNVLEKE QLQDHATSVG SFLMQLLGQQ KIKHPIVGDV 
       370        380        390        400        410        420 
RGVGLFIGVD LIKDEATRTP ATEEAAYLVS RLKENYVLLS TDGPGRNILK FKPPMCFSLD 
       430        440        450    
NARQVVAKLD AILTDMEEKV RSCETLRLQP 

Isoforms

- Isoform 2 of 5-phosphohydroxy-L-lysine phospho-lyase - Isoform 3 of 5-phosphohydroxy-L-lysine phospho-lyase

Sequence View

        10         20         30         40         50         60 
MAADQRPKAD TLALRQRLIS SSCRLFFPED PVKIVRAQGQ YMYDEQGAEY IDCISNVAHV 
        70         80         90        100        110        120 
GHCHPLVVQA AHEQNQVLNT NSRYLHDNIV DYAQRLSETL PEQLCVFYFL NSGSEANDLA 
       130        140        150        160        170        180 
LRLARHYTGH QDVVVLDHAY HGHLSSLIDI SPYKFRNLDG QKEWVHVAPL PDTYRGPYRE 
       190        200        210        220        230        240 
DHPNPAMAYA NEVKRVVSSA QEKGRKIAAF FAESLPSVGG QIIPPAGYFS QVAEHIRKAG 
       250        260        270        280        290        300 
GVFVADEIQV GFGRVGKHFW AFQLQGKDFV PDIVTMGKSI GNGHPVACVA ATQPVARAFE 
       310        320        330        340        350        360 
ATGVEYFNTF GGSPVSCAVG LAVLNVLEKE QLQDHATSVG SFLMQLLGQQ KIKHPIVGDV 
       370        380        390        400        410        420 
RGVGLFIGVD LIKDEATRTP ATEEAAYLVS RLKENYVLLS TDGPGRNILK FKPPMCFSLD 
       430        440        450    
NARQVVAKLD AILTDMEEKV RSCETLRLQP          10         20         30         40         50         60 
MAADQRPKAD TLALRQRLIS SSCRLFFPED PVKIVRAQGQ YMYDEQGAEY IDCISNVAHV 
        70         80         90        100        110        120 
GHCHPLVVQA AHEQNQVLNT NSRYLHDNIV DYAQRLSETL PEQLCVFYFL NSGSEANDLA 
       130        140        150        160        170        180 
LRLARHYTGH QDVVVLDHAY HGHLSSLIDI SPYKFRNLDG QKEWVHVAPL PDTYRGPYRE 
       190        200        210        220        230        240 
DHPNPAMAYA NEVKRVVSSA QEKGRKIAAF FAESLPSVGG QIIPPAGYFS QVAEHIRKAG 
       250        260        270        280        290        300 
GVFVADEIQV GFGRVGKHFW AFQLQGKDFV PDIVTMGKSI GNGHPVACVA ATQPVARAFE 
       310        320        330        340        350        360 
ATGVEYFNTF GGSPVSCAVG LAVLNVLEKE QLQDHATSVG SFLMQLLGQQ KIKHPIVGDV 
       370        380        390        400        410        420 
RGVGLFIGVD LIKDEATRTP ATEEAAYLVS RLKENYVLLS TDGPGRNILK FKPPMCFSLD 
       430        440        450    
NARQVVAKLD AILTDMEEKV RSCETLRLQP 



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IUZ5-1-unknown MAADQR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IUZ5-276-unknown MGKSIG... 276 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt67796
    Q8IUZ5-344-unknown MQLLGQ... 344 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt67795
    Q8IUZ5-344-unknown MQLLGQ... 344 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt107691

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)