TopFIND 4.0

Q8IV77: Cyclic nucleotide-gated cation channel alpha-4

General Information

Protein names
- Cyclic nucleotide-gated cation channel alpha-4
- Cyclic nucleotide-gated channel alpha-4
- CNG channel alpha-4
- CNG-4
- CNG4
Gene names CNGA4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IV77

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSQDTKVKTT ESSPPAPSKA RKLLPVLDPS GDYYYWWLNT MVFPVMYNLI ILVCRACFPD 
        70         80         90        100        110        120 
LQHGYLVAWL VLDYTSDLLY LLDMVVRFHT GFLEQGILVV DKGRISSRYV RTWSFFLDLA 
       130        140        150        160        170        180 
SLMPTDVVYV RLGPHTPTLR LNRFLRAPRL FEAFDRTETR TAYPNAFRIA KLMLYIFVVI 
       190        200        210        220        230        240 
HWNSCLYFAL SRYLGFGRDA WVYPDPAQPG FERLRRQYLY SFYFSTLILT TVGDTPPPAR 
       250        260        270        280        290        300 
EEEYLFMVGD FLLAVMGFAT IMGSMSSVIY NMNTADAAFY PDHALVKKYM KLQHVNRKLE 
       310        320        330        340        350        360 
RRVIDWYQHL QINKKMTNEV AILQHLPERL RAEVAVSVHL STLSRVQIFQ NCEASLLEEL 
       370        380        390        400        410        420 
VLKLQPQTYS PGEYVCRKGD IGQEMYIIRE GQLAVVADDG ITQYAVLGAG LYFGEISIIN 
       430        440        450        460        470        480 
IKGNMSGNRR TANIKSLGYS DLFCLSKEDL REVLSEYPQA QTIMEEKGRE ILLKMNKLDV 
       490        500        510        520        530        540 
NAEAAEIALQ EATESRLRGL DQQLDDLQTK FARLLAELES SALKIAYRIE RLEWQTREWP 
       550        560        570    
MPEDLAEADD EGEPEEGTSK DEEGRASQEG PPGPE

Isoforms

- Isoform 2 of Cyclic nucleotide-gated cation channel alpha-4

Sequence View

        10         20         30         40         50         60 
MSQDTKVKTT ESSPPAPSKA RKLLPVLDPS GDYYYWWLNT MVFPVMYNLI ILVCRACFPD 
        70         80         90        100        110        120 
LQHGYLVAWL VLDYTSDLLY LLDMVVRFHT GFLEQGILVV DKGRISSRYV RTWSFFLDLA 
       130        140        150        160        170        180 
SLMPTDVVYV RLGPHTPTLR LNRFLRAPRL FEAFDRTETR TAYPNAFRIA KLMLYIFVVI 
       190        200        210        220        230        240 
HWNSCLYFAL SRYLGFGRDA WVYPDPAQPG FERLRRQYLY SFYFSTLILT TVGDTPPPAR 
       250        260        270        280        290        300 
EEEYLFMVGD FLLAVMGFAT IMGSMSSVIY NMNTADAAFY PDHALVKKYM KLQHVNRKLE 
       310        320        330        340        350        360 
RRVIDWYQHL QINKKMTNEV AILQHLPERL RAEVAVSVHL STLSRVQIFQ NCEASLLEEL 
       370        380        390        400        410        420 
VLKLQPQTYS PGEYVCRKGD IGQEMYIIRE GQLAVVADDG ITQYAVLGAG LYFGEISIIN 
       430        440        450        460        470        480 
IKGNMSGNRR TANIKSLGYS DLFCLSKEDL REVLSEYPQA QTIMEEKGRE ILLKMNKLDV 
       490        500        510        520        530        540 
NAEAAEIALQ EATESRLRGL DQQLDDLQTK FARLLAELES SALKIAYRIE RLEWQTREWP 
       550        560        570    
MPEDLAEADD EGEPEEGTSK DEEGRASQEG PPGPE



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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IV77-1-unknown MSQDTK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IV77-41-unknown MVFPVM... 41 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71127

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PPGPE 575 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)