Q8IVL0: Neuron navigator 3
Protein names | - Neuron navigator 3 - Pore membrane and/or filament-interacting-like protein 1 - Steerin-3 - Unc-53 homolog 3 - unc53H3 |
---|---|
Gene names | NAV3 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q8IVL0 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPVLGVASKL RQPAVGSKPV HTALPIPNLG TTGSQHCSSR PLELTETESS MLSCQLALKS
70 80 90 100 110 120
TCEFGEKKPL QGKAKEKEDS KIYTDWANHY LAKSGHKRLI KDLQQDIADG VLLAEIIQII
130 140 150 160 170 180
ANEKVEDING CPRSQSQMIE NVDVCLSFLA ARGVNVQGLS AEEIRNGNLK AILGLFFSLS
190 200 210 220 230 240
RYKQQQHHQQ QYYQSLVELQ QRVTHASPPS EASQAKTQQD MQSSLAARYA TQSNHSGIAT
250 260 270 280 290 300
SQKKPTRLPG PSRVPAAGSS SKVQGASNLN RRSQSFNSID KNKPPNYANG NEKDSSKGPQ
310 320 330 340 350 360
SSSGVNGNVQ PPSTAGQPPA SAIPSPSASK PWRSKSMNVK HSATSTMLTV KQSSTATSPT
370 380 390 400 410 420
PSSDRLKPPV SEGVKTAPSG QKSMLEKFKL VNARTALRPP QPPSSGPSDG GKDDDAFSES
430 440 450 460 470 480
GEMEGFNSGL NSGGSTNSSP KVSPKLAPPK AGSKNLSNKK SLLQPKEKEE KNRDKNKVCT
490 500 510 520 530 540
EKPVKEEKDQ VTEMAPKKTS KIASLIPKGS KTTAAKKESL IPSSSGIPKP GSKVPTVKQT
550 560 570 580 590 600
ISPGSTASKE SEKFRTTKGS PSQSLSKPIT MEKASASSCP APLEGREAGQ ASPSGSCTMT
610 620 630 640 650 660
VAQSSGQSTG NGAVQLPQQQ QHSHPNTATV APFIYRAHSE NEGTALPSAD SCTSPTKMDL
670 680 690 700 710 720
SYSKTAKQCL EEISGEDPET RRMRTVKNIA DLRQNLEETM SSLRGTQISH STLETTFDST
730 740 750 760 770 780
VTTEVNGRTI PNLTSRPTPM TWRLGQACPR LQAGDAPSLG AGYPRSGTSR FIHTDPSRFM
790 800 810 820 830 840
YTTPLRRAAV SRLGNMSQID MSEKASSDLD MSSEVDVGGY MSDGDILGKS LRTDDINSGY
850 860 870 880 890 900
MTDGGLNLYT RSLNRIPDTA TSRDIIQRGV HDVTVDADSW DDSSSVSSGL SDTLDNISTD
910 920 930 940 950 960
DLNTTSSVSS YSNITVPSRK NTQLRTDSEK RSTTDETWDS PEELKKPEED FDSHGDAGGK
970 980 990 1000 1010 1020
WKTVSSGLPE DPEKAGQKAS LSVSQTGSWR RGMSAQGGAP SRQKAGTSAL KTPGKTDDAK
1030 1040 1050 1060 1070 1080
ASEKGKAPLK GSSLQRSPSD AGKSSGDEGK KPPSGIGRST ATSSFGFKKP SGVGSSAMIT
1090 1100 1110 1120 1130 1140
SSGATITSGS ATLGKIPKSA AIGGKSNAGR KTSLDGSQNQ DDVVLHVSSK TTLQYRSLPR
1150 1160 1170 1180 1190 1200
PSKSSTSGIP GRGGHRSSTS SIDSNVSSKS AGATTSKLRE PTKIGSGRSS PVTVNQTDKE
1210 1220 1230 1240 1250 1260
KEKVAVSDSE SVSLSGSPKS SPTSASACGA QGLRQPGSKY PDIASPTFRR LFGAKAGGKS
1270 1280 1290 1300 1310 1320
ASAPNTEGVK SSSVMPSPST TLARQGSLES PSSGTGSMGS AGGLSGSSSP LFNKPSDLTT
1330 1340 1350 1360 1370 1380
DVISLSHSLA SSPASVHSFT SGGLVWAANM SSSSAGSKDT PSYQSMTSLH TSSESIDLPL
1390 1400 1410 1420 1430 1440
SHHGSLSGLT TGTHEVQSLL MRTGSVRSTL SESMQLDRNT LPKKGLRYTP SSRQANQEEG
1450 1460 1470 1480 1490 1500
KEWLRSHSTG GLQDTGNQSP LVSPSAMSSS AAGKYHFSNL VSPTNLSQFN LPGPSMMRSN
1510 1520 1530 1540 1550 1560
SIPAQDSSFD LYDDSQLCGS ATSLEERPRA ISHSGSFRDS MEEVHGSSLS LVSSTSSLYS
1570 1580 1590 1600 1610 1620
TAEEKAHSEQ IHKLRRELVA SQEKVATLTS QLSANAHLVA AFEKSLGNMT GRLQSLTMTA
1630 1640 1650 1660 1670 1680
EQKESELIEL RETIEMLKAQ NSAAQAAIQG ALNGPDHPPK DLRIRRQHSS ESVSSINSAT
1690 1700 1710 1720 1730 1740
SHSSIGSGND ADSKKKKKKN WVNSRGSELR SSFKQAFGKK KSTKPPSSHS DIEELTDSSL
1750 1760 1770 1780 1790 1800
PASPKLPHNA GDCGSASMKP SQSASASPLV WPPKKRQNGP VIYKHRSRIC ECTEAEAEII
1810 1820 1830 1840 1850 1860
LQLKSELREK ELKLTDIRLE ALSSAHHLDQ IREAMNRMQN EIEILKAEND RLKAETGNTA
1870 1880 1890 1900 1910 1920
KPTRPPSESS SSTSSSSSRQ SLGLSLNNLN ITEAVSSDIL LDDAGDATGH KDGRSVKIIV
1930 1940 1950 1960 1970 1980
SISKGYGRAK DQKSQAYLIG SIGVSGKTKW DVLDGVIRRL FKEYVFRIDT STSLGLSSDC
1990 2000 2010 2020 2030 2040
IASYCIGDLI RSHNLEVPEL LPCGYLVGDN NIITVNLKGV EENSLDSFVF DTLIPKPITQ
2050 2060 2070 2080 2090 2100
RYFNLLMEHH RIILSGPSGT GKTYLANKLA EYVITKSGRK KTEDAIATFN VDHKSSKELQ
2110 2120 2130 2140 2150 2160
QYLANLAEQC SADNNGVELP VVIILDNLHH VGSLSDIFNG FLNCKYNKCP YIIGTMNQGV
2170 2180 2190 2200 2210 2220
SSSPNLELHH NFRWVLCANH TEPVKGFLGR YLRRKLIEIE IERNIRNNDL VKIIDWIPKT
2230 2240 2250 2260 2270 2280
WHHLNSFLET HSSSDVTIGP RLFLPCPMDV EGSRVWFMDL WNYSLVPYIL EAVREGLQMY
2290 2300 2310 2320 2330 2340
GKRTPWEDPS KWVLDTYPWS SATLPQESPA LLQLRPEDVG YESCTSTKEA TTSKHIPQTD
2350 2360 2370 2380
TEGDPLMNML MKLQEAANYS STQSCDSEST SHHEDILDSS LESTL
Isoforms
- Isoform 2 of Neuron navigator 3 - Isoform 3 of Neuron navigator 3Sequence View
10 20 30 40 50 60
MPVLGVASKL RQPAVGSKPV HTALPIPNLG TTGSQHCSSR PLELTETESS MLSCQLALKS
70 80 90 100 110 120
TCEFGEKKPL QGKAKEKEDS KIYTDWANHY LAKSGHKRLI KDLQQDIADG VLLAEIIQII
130 140 150 160 170 180
ANEKVEDING CPRSQSQMIE NVDVCLSFLA ARGVNVQGLS AEEIRNGNLK AILGLFFSLS
190 200 210 220 230 240
RYKQQQHHQQ QYYQSLVELQ QRVTHASPPS EASQAKTQQD MQSSLAARYA TQSNHSGIAT
250 260 270 280 290 300
SQKKPTRLPG PSRVPAAGSS SKVQGASNLN RRSQSFNSID KNKPPNYANG NEKDSSKGPQ
310 320 330 340 350 360
SSSGVNGNVQ PPSTAGQPPA SAIPSPSASK PWRSKSMNVK HSATSTMLTV KQSSTATSPT
370 380 390 400 410 420
PSSDRLKPPV SEGVKTAPSG QKSMLEKFKL VNARTALRPP QPPSSGPSDG GKDDDAFSES
430 440 450 460 470 480
GEMEGFNSGL NSGGSTNSSP KVSPKLAPPK AGSKNLSNKK SLLQPKEKEE KNRDKNKVCT
490 500 510 520 530 540
EKPVKEEKDQ VTEMAPKKTS KIASLIPKGS KTTAAKKESL IPSSSGIPKP GSKVPTVKQT
550 560 570 580 590 600
ISPGSTASKE SEKFRTTKGS PSQSLSKPIT MEKASASSCP APLEGREAGQ ASPSGSCTMT
610 620 630 640 650 660
VAQSSGQSTG NGAVQLPQQQ QHSHPNTATV APFIYRAHSE NEGTALPSAD SCTSPTKMDL
670 680 690 700 710 720
SYSKTAKQCL EEISGEDPET RRMRTVKNIA DLRQNLEETM SSLRGTQISH STLETTFDST
730 740 750 760 770 780
VTTEVNGRTI PNLTSRPTPM TWRLGQACPR LQAGDAPSLG AGYPRSGTSR FIHTDPSRFM
790 800 810 820 830 840
YTTPLRRAAV SRLGNMSQID MSEKASSDLD MSSEVDVGGY MSDGDILGKS LRTDDINSGY
850 860 870 880 890 900
MTDGGLNLYT RSLNRIPDTA TSRDIIQRGV HDVTVDADSW DDSSSVSSGL SDTLDNISTD
910 920 930 940 950 960
DLNTTSSVSS YSNITVPSRK NTQLRTDSEK RSTTDETWDS PEELKKPEED FDSHGDAGGK
970 980 990 1000 1010 1020
WKTVSSGLPE DPEKAGQKAS LSVSQTGSWR RGMSAQGGAP SRQKAGTSAL KTPGKTDDAK
1030 1040 1050 1060 1070 1080
ASEKGKAPLK GSSLQRSPSD AGKSSGDEGK KPPSGIGRST ATSSFGFKKP SGVGSSAMIT
1090 1100 1110 1120 1130 1140
SSGATITSGS ATLGKIPKSA AIGGKSNAGR KTSLDGSQNQ DDVVLHVSSK TTLQYRSLPR
1150 1160 1170 1180 1190 1200
PSKSSTSGIP GRGGHRSSTS SIDSNVSSKS AGATTSKLRE PTKIGSGRSS PVTVNQTDKE
1210 1220 1230 1240 1250 1260
KEKVAVSDSE SVSLSGSPKS SPTSASACGA QGLRQPGSKY PDIASPTFRR LFGAKAGGKS
1270 1280 1290 1300 1310 1320
ASAPNTEGVK SSSVMPSPST TLARQGSLES PSSGTGSMGS AGGLSGSSSP LFNKPSDLTT
1330 1340 1350 1360 1370 1380
DVISLSHSLA SSPASVHSFT SGGLVWAANM SSSSAGSKDT PSYQSMTSLH TSSESIDLPL
1390 1400 1410 1420 1430 1440
SHHGSLSGLT TGTHEVQSLL MRTGSVRSTL SESMQLDRNT LPKKGLRYTP SSRQANQEEG
1450 1460 1470 1480 1490 1500
KEWLRSHSTG GLQDTGNQSP LVSPSAMSSS AAGKYHFSNL VSPTNLSQFN LPGPSMMRSN
1510 1520 1530 1540 1550 1560
SIPAQDSSFD LYDDSQLCGS ATSLEERPRA ISHSGSFRDS MEEVHGSSLS LVSSTSSLYS
1570 1580 1590 1600 1610 1620
TAEEKAHSEQ IHKLRRELVA SQEKVATLTS QLSANAHLVA AFEKSLGNMT GRLQSLTMTA
1630 1640 1650 1660 1670 1680
EQKESELIEL RETIEMLKAQ NSAAQAAIQG ALNGPDHPPK DLRIRRQHSS ESVSSINSAT
1690 1700 1710 1720 1730 1740
SHSSIGSGND ADSKKKKKKN WVNSRGSELR SSFKQAFGKK KSTKPPSSHS DIEELTDSSL
1750 1760 1770 1780 1790 1800
PASPKLPHNA GDCGSASMKP SQSASASPLV WPPKKRQNGP VIYKHRSRIC ECTEAEAEII
1810 1820 1830 1840 1850 1860
LQLKSELREK ELKLTDIRLE ALSSAHHLDQ IREAMNRMQN EIEILKAEND RLKAETGNTA
1870 1880 1890 1900 1910 1920
KPTRPPSESS SSTSSSSSRQ SLGLSLNNLN ITEAVSSDIL LDDAGDATGH KDGRSVKIIV
1930 1940 1950 1960 1970 1980
SISKGYGRAK DQKSQAYLIG SIGVSGKTKW DVLDGVIRRL FKEYVFRIDT STSLGLSSDC
1990 2000 2010 2020 2030 2040
IASYCIGDLI RSHNLEVPEL LPCGYLVGDN NIITVNLKGV EENSLDSFVF DTLIPKPITQ
2050 2060 2070 2080 2090 2100
RYFNLLMEHH RIILSGPSGT GKTYLANKLA EYVITKSGRK KTEDAIATFN VDHKSSKELQ
2110 2120 2130 2140 2150 2160
QYLANLAEQC SADNNGVELP VVIILDNLHH VGSLSDIFNG FLNCKYNKCP YIIGTMNQGV
2170 2180 2190 2200 2210 2220
SSSPNLELHH NFRWVLCANH TEPVKGFLGR YLRRKLIEIE IERNIRNNDL VKIIDWIPKT
2230 2240 2250 2260 2270 2280
WHHLNSFLET HSSSDVTIGP RLFLPCPMDV EGSRVWFMDL WNYSLVPYIL EAVREGLQMY
2290 2300 2310 2320 2330 2340
GKRTPWEDPS KWVLDTYPWS SATLPQESPA LLQLRPEDVG YESCTSTKEA TTSKHIPQTD
2350 2360 2370 2380
TEGDPLMNML MKLQEAANYS STQSCDSEST SHHEDILDSS LESTL
10 20 30 40 50 60
MPVLGVASKL RQPAVGSKPV HTALPIPNLG TTGSQHCSSR PLELTETESS MLSCQLALKS
70 80 90 100 110 120
TCEFGEKKPL QGKAKEKEDS KIYTDWANHY LAKSGHKRLI KDLQQDIADG VLLAEIIQII
130 140 150 160 170 180
ANEKVEDING CPRSQSQMIE NVDVCLSFLA ARGVNVQGLS AEEIRNGNLK AILGLFFSLS
190 200 210 220 230 240
RYKQQQHHQQ QYYQSLVELQ QRVTHASPPS EASQAKTQQD MQSSLAARYA TQSNHSGIAT
250 260 270 280 290 300
SQKKPTRLPG PSRVPAAGSS SKVQGASNLN RRSQSFNSID KNKPPNYANG NEKDSSKGPQ
310 320 330 340 350 360
SSSGVNGNVQ PPSTAGQPPA SAIPSPSASK PWRSKSMNVK HSATSTMLTV KQSSTATSPT
370 380 390 400 410 420
PSSDRLKPPV SEGVKTAPSG QKSMLEKFKL VNARTALRPP QPPSSGPSDG GKDDDAFSES
430 440 450 460 470 480
GEMEGFNSGL NSGGSTNSSP KVSPKLAPPK AGSKNLSNKK SLLQPKEKEE KNRDKNKVCT
490 500 510 520 530 540
EKPVKEEKDQ VTEMAPKKTS KIASLIPKGS KTTAAKKESL IPSSSGIPKP GSKVPTVKQT
550 560 570 580 590 600
ISPGSTASKE SEKFRTTKGS PSQSLSKPIT MEKASASSCP APLEGREAGQ ASPSGSCTMT
610 620 630 640 650 660
VAQSSGQSTG NGAVQLPQQQ QHSHPNTATV APFIYRAHSE NEGTALPSAD SCTSPTKMDL
670 680 690 700 710 720
SYSKTAKQCL EEISGEDPET RRMRTVKNIA DLRQNLEETM SSLRGTQISH STLETTFDST
730 740 750 760 770 780
VTTEVNGRTI PNLTSRPTPM TWRLGQACPR LQAGDAPSLG AGYPRSGTSR FIHTDPSRFM
790 800 810 820 830 840
YTTPLRRAAV SRLGNMSQID MSEKASSDLD MSSEVDVGGY MSDGDILGKS LRTDDINSGY
850 860 870 880 890 900
MTDGGLNLYT RSLNRIPDTA TSRDIIQRGV HDVTVDADSW DDSSSVSSGL SDTLDNISTD
910 920 930 940 950 960
DLNTTSSVSS YSNITVPSRK NTQLRTDSEK RSTTDETWDS PEELKKPEED FDSHGDAGGK
970 980 990 1000 1010 1020
WKTVSSGLPE DPEKAGQKAS LSVSQTGSWR RGMSAQGGAP SRQKAGTSAL KTPGKTDDAK
1030 1040 1050 1060 1070 1080
ASEKGKAPLK GSSLQRSPSD AGKSSGDEGK KPPSGIGRST ATSSFGFKKP SGVGSSAMIT
1090 1100 1110 1120 1130 1140
SSGATITSGS ATLGKIPKSA AIGGKSNAGR KTSLDGSQNQ DDVVLHVSSK TTLQYRSLPR
1150 1160 1170 1180 1190 1200
PSKSSTSGIP GRGGHRSSTS SIDSNVSSKS AGATTSKLRE PTKIGSGRSS PVTVNQTDKE
1210 1220 1230 1240 1250 1260
KEKVAVSDSE SVSLSGSPKS SPTSASACGA QGLRQPGSKY PDIASPTFRR LFGAKAGGKS
1270 1280 1290 1300 1310 1320
ASAPNTEGVK SSSVMPSPST TLARQGSLES PSSGTGSMGS AGGLSGSSSP LFNKPSDLTT
1330 1340 1350 1360 1370 1380
DVISLSHSLA SSPASVHSFT SGGLVWAANM SSSSAGSKDT PSYQSMTSLH TSSESIDLPL
1390 1400 1410 1420 1430 1440
SHHGSLSGLT TGTHEVQSLL MRTGSVRSTL SESMQLDRNT LPKKGLRYTP SSRQANQEEG
1450 1460 1470 1480 1490 1500
KEWLRSHSTG GLQDTGNQSP LVSPSAMSSS AAGKYHFSNL VSPTNLSQFN LPGPSMMRSN
1510 1520 1530 1540 1550 1560
SIPAQDSSFD LYDDSQLCGS ATSLEERPRA ISHSGSFRDS MEEVHGSSLS LVSSTSSLYS
1570 1580 1590 1600 1610 1620
TAEEKAHSEQ IHKLRRELVA SQEKVATLTS QLSANAHLVA AFEKSLGNMT GRLQSLTMTA
1630 1640 1650 1660 1670 1680
EQKESELIEL RETIEMLKAQ NSAAQAAIQG ALNGPDHPPK DLRIRRQHSS ESVSSINSAT
1690 1700 1710 1720 1730 1740
SHSSIGSGND ADSKKKKKKN WVNSRGSELR SSFKQAFGKK KSTKPPSSHS DIEELTDSSL
1750 1760 1770 1780 1790 1800
PASPKLPHNA GDCGSASMKP SQSASASPLV WPPKKRQNGP VIYKHRSRIC ECTEAEAEII
1810 1820 1830 1840 1850 1860
LQLKSELREK ELKLTDIRLE ALSSAHHLDQ IREAMNRMQN EIEILKAEND RLKAETGNTA
1870 1880 1890 1900 1910 1920
KPTRPPSESS SSTSSSSSRQ SLGLSLNNLN ITEAVSSDIL LDDAGDATGH KDGRSVKIIV
1930 1940 1950 1960 1970 1980
SISKGYGRAK DQKSQAYLIG SIGVSGKTKW DVLDGVIRRL FKEYVFRIDT STSLGLSSDC
1990 2000 2010 2020 2030 2040
IASYCIGDLI RSHNLEVPEL LPCGYLVGDN NIITVNLKGV EENSLDSFVF DTLIPKPITQ
2050 2060 2070 2080 2090 2100
RYFNLLMEHH RIILSGPSGT GKTYLANKLA EYVITKSGRK KTEDAIATFN VDHKSSKELQ
2110 2120 2130 2140 2150 2160
QYLANLAEQC SADNNGVELP VVIILDNLHH VGSLSDIFNG FLNCKYNKCP YIIGTMNQGV
2170 2180 2190 2200 2210 2220
SSSPNLELHH NFRWVLCANH TEPVKGFLGR YLRRKLIEIE IERNIRNNDL VKIIDWIPKT
2230 2240 2250 2260 2270 2280
WHHLNSFLET HSSSDVTIGP RLFLPCPMDV EGSRVWFMDL WNYSLVPYIL EAVREGLQMY
2290 2300 2310 2320 2330 2340
GKRTPWEDPS KWVLDTYPWS SATLPQESPA LLQLRPEDVG YESCTSTKEA TTSKHIPQTD
2350 2360 2370 2380
TEGDPLMNML MKLQEAANYS STQSCDSEST SHHEDILDSS LESTL
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8IVL0-1-unknown | MPVLGV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q8IVL0-1-unknown | MPVLGV... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt82324 | |||
Q8IVL0-1-unknown | MPVLGV... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt82325 | |||
Q8IVL0-844-unknown | GGLNLY... | 844 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1320 | |||
Q8IVL0-844-unknown | GGLNLY... | 844 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156664 | |||
Q8IVL0-844-unknown | GGLNLY... | 844 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156665 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GYMTDG | 843 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1320 | |||
...GYMTDG | 843 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140149 | |||
...GYMTDG | 843 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140150 | |||
...LESTL | 2385 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...LESTL | 2385 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt77943 | |||
...LESTL | 2385 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt77942 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CASP1_HUMAN | 843 | MTDG.|.GGLN | inferred from experiment | unknown | MEROPS | Wells JA | Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001) | 20173201, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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