Q8IVS8: Glycerate kinase

General Information

Protein names	- Glycerate kinase - 2.7.1.31 {ECO:0000269\|PubMed:16753811, ECO:0000269\|PubMed:20949620} - HBeAg-binding protein 4
Gene names	GLYCTK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8IVS8

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Glycerate kinase - Isoform 3 of Glycerate kinase - Isoform 4 of Glycerate kinase - Isoform 5 of Glycerate kinase - Isoform 6 of Glycerate kinase - Isoform 7 of Glycerate kinase

Sequence View

        10         20         30         40         50         60
MAAALQVLPR LARAPLHPLL WRGSVARLAS SMALAEQARQ LFESAVGAVL PGPMLHRALS
        70         80         90        100        110        120
LDPGGRQLKV RDRNFQLRQN LYLVGFGKAV LGMAAAAEEL LGQHLVQGVI SVPKGIRAAM
       130        140        150        160        170        180
ERAGKQEMLL KPHSRVQVFE GAEDNLPDRD ALRAALAIQQ LAEGLTADDL LLVLISGGGS
       190        200        210        220        230        240
ALLPAPIPPV TLEEKQTLTR LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI
       250        260        270        280        290        300
LSDVVGDPVE VIASGPTVAS SHNVQDCLHI LNRYGLRAAL PRSVKTVLSR ADSDPHGPHT
       310        320        330        340        350        360
CGHVLNVIIG SNVLALAEAQ RQAEALGYQA VVLSAAMQGD VKSMAQFYGL LAHVARTRLT
       370        380        390        400        410        420
PSMAGASVEE DAQLHELAAE LQIPDLQLEE ALETMAWGRG PVCLLAGGEP TVQLQGSGRG
       430        440        450        460        470        480
GRNQELALRV GAELRRWPLG PIDVLFLSGG TDGQDGPTEA AGAWVTPELA SQAAAEGLDI
       490        500        510        520
ATFLAHNDSH TFFCCLQGGA HLLHTGMTGT NVMDTHLLFL RPR         10         20         30         40         50         60
MAAALQVLPR LARAPLHPLL WRGSVARLAS SMALAEQARQ LFESAVGAVL PGPMLHRALS
        70         80         90        100        110        120
LDPGGRQLKV RDRNFQLRQN LYLVGFGKAV LGMAAAAEEL LGQHLVQGVI SVPKGIRAAM
       130        140        150        160        170        180
ERAGKQEMLL KPHSRVQVFE GAEDNLPDRD ALRAALAIQQ LAEGLTADDL LLVLISGGGS
       190        200        210        220        230        240
ALLPAPIPPV TLEEKQTLTR LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI
       250        260        270        280        290        300
LSDVVGDPVE VIASGPTVAS SHNVQDCLHI LNRYGLRAAL PRSVKTVLSR ADSDPHGPHT
       310        320        330        340        350        360
CGHVLNVIIG SNVLALAEAQ RQAEALGYQA VVLSAAMQGD VKSMAQFYGL LAHVARTRLT
       370        380        390        400        410        420
PSMAGASVEE DAQLHELAAE LQIPDLQLEE ALETMAWGRG PVCLLAGGEP TVQLQGSGRG
       430        440        450        460        470        480
GRNQELALRV GAELRRWPLG PIDVLFLSGG TDGQDGPTEA AGAWVTPELA SQAAAEGLDI
       490        500        510        520
ATFLAHNDSH TFFCCLQGGA HLLHTGMTGT NVMDTHLLFL RPR         10         20         30         40         50         60
MAAALQVLPR LARAPLHPLL WRGSVARLAS SMALAEQARQ LFESAVGAVL PGPMLHRALS
        70         80         90        100        110        120
LDPGGRQLKV RDRNFQLRQN LYLVGFGKAV LGMAAAAEEL LGQHLVQGVI SVPKGIRAAM
       130        140        150        160        170        180
ERAGKQEMLL KPHSRVQVFE GAEDNLPDRD ALRAALAIQQ LAEGLTADDL LLVLISGGGS
       190        200        210        220        230        240
ALLPAPIPPV TLEEKQTLTR LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI
       250        260        270        280        290        300
LSDVVGDPVE VIASGPTVAS SHNVQDCLHI LNRYGLRAAL PRSVKTVLSR ADSDPHGPHT
       310        320        330        340        350        360
CGHVLNVIIG SNVLALAEAQ RQAEALGYQA VVLSAAMQGD VKSMAQFYGL LAHVARTRLT
       370        380        390        400        410        420
PSMAGASVEE DAQLHELAAE LQIPDLQLEE ALETMAWGRG PVCLLAGGEP TVQLQGSGRG
       430        440        450        460        470        480
GRNQELALRV GAELRRWPLG PIDVLFLSGG TDGQDGPTEA AGAWVTPELA SQAAAEGLDI
       490        500        510        520
ATFLAHNDSH TFFCCLQGGA HLLHTGMTGT NVMDTHLLFL RPR         10         20         30         40         50         60
MAAALQVLPR LARAPLHPLL WRGSVARLAS SMALAEQARQ LFESAVGAVL PGPMLHRALS
        70         80         90        100        110        120
LDPGGRQLKV RDRNFQLRQN LYLVGFGKAV LGMAAAAEEL LGQHLVQGVI SVPKGIRAAM
       130        140        150        160        170        180
ERAGKQEMLL KPHSRVQVFE GAEDNLPDRD ALRAALAIQQ LAEGLTADDL LLVLISGGGS
       190        200        210        220        230        240
ALLPAPIPPV TLEEKQTLTR LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI
       250        260        270        280        290        300
LSDVVGDPVE VIASGPTVAS SHNVQDCLHI LNRYGLRAAL PRSVKTVLSR ADSDPHGPHT
       310        320        330        340        350        360
CGHVLNVIIG SNVLALAEAQ RQAEALGYQA VVLSAAMQGD VKSMAQFYGL LAHVARTRLT
       370        380        390        400        410        420
PSMAGASVEE DAQLHELAAE LQIPDLQLEE ALETMAWGRG PVCLLAGGEP TVQLQGSGRG
       430        440        450        460        470        480
GRNQELALRV GAELRRWPLG PIDVLFLSGG TDGQDGPTEA AGAWVTPELA SQAAAEGLDI
       490        500        510        520
ATFLAHNDSH TFFCCLQGGA HLLHTGMTGT NVMDTHLLFL RPR         10         20         30         40         50         60
MAAALQVLPR LARAPLHPLL WRGSVARLAS SMALAEQARQ LFESAVGAVL PGPMLHRALS
        70         80         90        100        110        120
LDPGGRQLKV RDRNFQLRQN LYLVGFGKAV LGMAAAAEEL LGQHLVQGVI SVPKGIRAAM
       130        140        150        160        170        180
ERAGKQEMLL KPHSRVQVFE GAEDNLPDRD ALRAALAIQQ LAEGLTADDL LLVLISGGGS
       190        200        210        220        230        240
ALLPAPIPPV TLEEKQTLTR LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI
       250        260        270        280        290        300
LSDVVGDPVE VIASGPTVAS SHNVQDCLHI LNRYGLRAAL PRSVKTVLSR ADSDPHGPHT
       310        320        330        340        350        360
CGHVLNVIIG SNVLALAEAQ RQAEALGYQA VVLSAAMQGD VKSMAQFYGL LAHVARTRLT
       370        380        390        400        410        420
PSMAGASVEE DAQLHELAAE LQIPDLQLEE ALETMAWGRG PVCLLAGGEP TVQLQGSGRG
       430        440        450        460        470        480
GRNQELALRV GAELRRWPLG PIDVLFLSGG TDGQDGPTEA AGAWVTPELA SQAAAEGLDI
       490        500        510        520
ATFLAHNDSH TFFCCLQGGA HLLHTGMTGT NVMDTHLLFL RPR         10         20         30         40         50         60
MAAALQVLPR LARAPLHPLL WRGSVARLAS SMALAEQARQ LFESAVGAVL PGPMLHRALS
        70         80         90        100        110        120
LDPGGRQLKV RDRNFQLRQN LYLVGFGKAV LGMAAAAEEL LGQHLVQGVI SVPKGIRAAM
       130        140        150        160        170        180
ERAGKQEMLL KPHSRVQVFE GAEDNLPDRD ALRAALAIQQ LAEGLTADDL LLVLISGGGS
       190        200        210        220        230        240
ALLPAPIPPV TLEEKQTLTR LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI
       250        260        270        280        290        300
LSDVVGDPVE VIASGPTVAS SHNVQDCLHI LNRYGLRAAL PRSVKTVLSR ADSDPHGPHT
       310        320        330        340        350        360
CGHVLNVIIG SNVLALAEAQ RQAEALGYQA VVLSAAMQGD VKSMAQFYGL LAHVARTRLT
       370        380        390        400        410        420
PSMAGASVEE DAQLHELAAE LQIPDLQLEE ALETMAWGRG PVCLLAGGEP TVQLQGSGRG
       430        440        450        460        470        480
GRNQELALRV GAELRRWPLG PIDVLFLSGG TDGQDGPTEA AGAWVTPELA SQAAAEGLDI
       490        500        510        520
ATFLAHNDSH TFFCCLQGGA HLLHTGMTGT NVMDTHLLFL RPR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8IVS8-1-unknown	MAAALQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8IVS8-1-unknown	MAAALQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76022
Q8IVS8-1-unknown	MAAALQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76023
Q8IVS8-1-unknown	MAAALQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76024
Q8IVS8-1-unknown	MAAALQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76027
Q8IVS8-128-unknown	MLLKPH...	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76025
Q8IVS8-128-unknown	MLLKPH...	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417526
Q8IVS8-128-unknown	MLLKPH...	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109707
Q8IVS8-128-unknown	MLLKPH...	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109708
Q8IVS8-128-unknown	MLLKPH...	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109709
Q8IVS8-337-unknown	MQGDVK...	337	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76026
Q8IVS8-337-unknown	MQGDVK...	337	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109758

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FLRPR	523	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FLRPR	523	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71644
...FLRPR	523	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71641

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)