TopFIND 4.0

Q8IXI1: Mitochondrial Rho GTPase 2

General Information

Protein names
- Mitochondrial Rho GTPase 2
- MIRO-2
- hMiro-2
- 3.6.5.-
- Ras homolog gene family member T2
Gene names RHOT2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IXI1

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRRDVRILLL GEAQVGKTSL ILSLVGEEFP EEVPPRAEEI TIPADVTPEK VPTHIVDYSE 
        70         80         90        100        110        120 
AEQTDEELRE EIHKANVVCV VYDVSEEATI EKIRTKWIPL VNGGTTQGPR VPIILVGNKS 
       130        140        150        160        170        180 
DLRSGSSMEA VLPIMSQFPE IETCVECSAK NLRNISELFY YAQKAVLHPT APLYDPEAKQ 
       190        200        210        220        230        240 
LRPACAQALT RIFRLSDQDL DQALSDEELN AFQKSCFGHP LAPQALEDVK TVVCRNVAGG 
       250        260        270        280        290        300 
VREDRLTLDG FLFLNTLFIQ RGRHETTWTI LRRFGYSDAL ELTADYLSPL IHVPPGCSTE 
       310        320        330        340        350        360 
LNHLGYQFVQ RVFEKHDQDR DGALSPVELQ SLFSVFPAAP WGPELPRTVR TEAGRLPLHG 
       370        380        390        400        410        420 
YLCQWTLVTY LDVRSCLGHL GYLGYPTLCE QDQAHAITVT REKRLDQEKG QTQRSVLLCK 
       430        440        450        460        470        480 
VVGARGVGKS AFLQAFLGRG LGHQDTREQP PGYAIDTVQV NGQEKYLILC EVGTDGLLAT 
       490        500        510        520        530        540 
SLDATCDVAC LMFDGSDPKS FAHCASVYKH HYMDGQTPCL FVSSKADLPE GVAVSGPSPA 
       550        560        570        580        590        600 
EFCRKHRLPA PVPFSCAGPA EPSTTIFTQL ATMAAFPHLV HAELHPSSFW LRGLLGVVGA 
       610    
AVAAVLSFSL YRVLVKSQ

Isoforms

- Isoform 2 of Mitochondrial Rho GTPase 2

Sequence View

        10         20         30         40         50         60 
MRRDVRILLL GEAQVGKTSL ILSLVGEEFP EEVPPRAEEI TIPADVTPEK VPTHIVDYSE 
        70         80         90        100        110        120 
AEQTDEELRE EIHKANVVCV VYDVSEEATI EKIRTKWIPL VNGGTTQGPR VPIILVGNKS 
       130        140        150        160        170        180 
DLRSGSSMEA VLPIMSQFPE IETCVECSAK NLRNISELFY YAQKAVLHPT APLYDPEAKQ 
       190        200        210        220        230        240 
LRPACAQALT RIFRLSDQDL DQALSDEELN AFQKSCFGHP LAPQALEDVK TVVCRNVAGG 
       250        260        270        280        290        300 
VREDRLTLDG FLFLNTLFIQ RGRHETTWTI LRRFGYSDAL ELTADYLSPL IHVPPGCSTE 
       310        320        330        340        350        360 
LNHLGYQFVQ RVFEKHDQDR DGALSPVELQ SLFSVFPAAP WGPELPRTVR TEAGRLPLHG 
       370        380        390        400        410        420 
YLCQWTLVTY LDVRSCLGHL GYLGYPTLCE QDQAHAITVT REKRLDQEKG QTQRSVLLCK 
       430        440        450        460        470        480 
VVGARGVGKS AFLQAFLGRG LGHQDTREQP PGYAIDTVQV NGQEKYLILC EVGTDGLLAT 
       490        500        510        520        530        540 
SLDATCDVAC LMFDGSDPKS FAHCASVYKH HYMDGQTPCL FVSSKADLPE GVAVSGPSPA 
       550        560        570        580        590        600 
EFCRKHRLPA PVPFSCAGPA EPSTTIFTQL ATMAAFPHLV HAELHPSSFW LRGLLGVVGA 
       610    
AVAAVLSFSL YRVLVKSQ



Filter Information:


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Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IXI1-1-unknown MRRDVR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IXI1-128-unknown MEAVLP... 128 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81169

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LVKSQ 618 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)