TopFIND 4.0

Q8IXK2: Polypeptide N-acetylgalactosaminyltransferase 12

General Information

Protein names
- Polypeptide N-acetylgalactosaminyltransferase 12
- 2.4.1.41
- Polypeptide GalNAc transferase 12
- GalNAc-T12
- pp-GaNTase 12
- Protein-UDP acetylgalactosaminyltransferase 12
- UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12
Gene names GALNT12
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IXK2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MWGRTARRRC PRELRRGREA LLVLLALLAL AGLGSVLRAQ RGAGAGAAEP GPPRTPRPGR 
        70         80         90        100        110        120 
REPVMPRPPV PANALGARGE AVRLQLQGEE LRLQEESVRL HQINIYLSDR ISLHRRLPER 
       130        140        150        160        170        180 
WNPLCKEKKY DYDNLPRTSV IIAFYNEAWS TLLRTVYSVL ETSPDILLEE VILVDDYSDR 
       190        200        210        220        230        240 
EHLKERLANE LSGLPKVRLI RANKREGLVR ARLLGASAAR GDVLTFLDCH CECHEGWLEP 
       250        260        270        280        290        300 
LLQRIHEEES AVVCPVIDVI DWNTFEYLGN SGEPQIGGFD WRLVFTWHTV PERERIRMQS 
       310        320        330        340        350        360 
PVDVIRSPTM AGGLFAVSKK YFEYLGSYDT GMEVWGGENL EFSFRIWQCG GVLETHPCSH 
       370        380        390        400        410        420 
VGHVFPKQAP YSRNKALANS VRAAEVWMDE FKELYYHRNP RARLEPFGDV TERKQLRDKL 
       430        440        450        460        470        480 
QCKDFKWFLE TVYPELHVPE DRPGFFGMLQ NKGLTDYCFD YNPPDENQIV GHQVILYLCH 
       490        500        510        520        530        540 
GMGQNQFFEY TSQKEIRYNT HQPEGCIAVE AGMDTLIMHL CEETAPENQK FILQEDGSLF 
       550        560        570        580    
HEQSKKCVQA ARKESSDSFV PLLRDCTNSD HQKWFFKERM L

Isoforms

- Isoform 2 of Polypeptide N-acetylgalactosaminyltransferase 12

Sequence View

        10         20         30         40         50         60 
MWGRTARRRC PRELRRGREA LLVLLALLAL AGLGSVLRAQ RGAGAGAAEP GPPRTPRPGR 
        70         80         90        100        110        120 
REPVMPRPPV PANALGARGE AVRLQLQGEE LRLQEESVRL HQINIYLSDR ISLHRRLPER 
       130        140        150        160        170        180 
WNPLCKEKKY DYDNLPRTSV IIAFYNEAWS TLLRTVYSVL ETSPDILLEE VILVDDYSDR 
       190        200        210        220        230        240 
EHLKERLANE LSGLPKVRLI RANKREGLVR ARLLGASAAR GDVLTFLDCH CECHEGWLEP 
       250        260        270        280        290        300 
LLQRIHEEES AVVCPVIDVI DWNTFEYLGN SGEPQIGGFD WRLVFTWHTV PERERIRMQS 
       310        320        330        340        350        360 
PVDVIRSPTM AGGLFAVSKK YFEYLGSYDT GMEVWGGENL EFSFRIWQCG GVLETHPCSH 
       370        380        390        400        410        420 
VGHVFPKQAP YSRNKALANS VRAAEVWMDE FKELYYHRNP RARLEPFGDV TERKQLRDKL 
       430        440        450        460        470        480 
QCKDFKWFLE TVYPELHVPE DRPGFFGMLQ NKGLTDYCFD YNPPDENQIV GHQVILYLCH 
       490        500        510        520        530        540 
GMGQNQFFEY TSQKEIRYNT HQPEGCIAVE AGMDTLIMHL CEETAPENQK FILQEDGSLF 
       550        560        570        580    
HEQSKKCVQA ARKESSDSFV PLLRDCTNSD HQKWFFKERM L



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IXK2-1-unknown MWGRTA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IXK2-310-unknown MAGGLF... 310 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76092

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KERML 581 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KERML 581 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt71710

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)