Q8IXQ5: Kelch-like protein 7

General Information

Protein names	- Kelch-like protein 7
Gene names	KLHL7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8IXQ5

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Kelch-like protein 7 - Isoform 3 of Kelch-like protein 7 - Isoform 4 of Kelch-like protein 7 - Isoform 5 of Kelch-like protein 7

Sequence View

        10         20         30         40         50         60
MAASGVEKSS KKKTEKKLAA REEAKLLAGF MGVMNNMRKQ KTLCDVILMV QERKIPAHRV
        70         80         90        100        110        120
VLAAASHFFN LMFTTNMLES KSFEVELKDA EPDIIEQLVE FAYTARISVN SNNVQSLLDA
       130        140        150        160        170        180
ANQYQIEPVK KMCVDFLKEQ VDASNCLGIS VLAECLDCPE LKATADDFIH QHFTEVYKTD
       190        200        210        220        230        240
EFLQLDVKRV THLLNQDTLT VRAEDQVYDA AVRWLKYDEP NRQPFMVDIL AKVRFPLISK
       250        260        270        280        290        300
NFLSKTVQAE PLIQDNPECL KMVISGMRYH LLSPEDREEL VDGTRPRRKK HDYRIALFGG
       310        320        330        340        350        360
SQPQSCRYFN PKDYSWTDIR CPFEKRRDAA CVFWDNVVYI LGGSQLFPIK RMDCYNVVKD
       370        380        390        400        410        420
SWYSKLGPPT PRDSLAACAA EGKIYTSGGS EVGNSALYLF ECYDTRTESW HTKPSMLTQR
       430        440        450        460        470        480
CSHGMVEANG LIYVCGGSLG NNVSGRVLNS CEVYDPATET WTELCPMIEA RKNHGLVFVK
       490        500        510        520        530        540
DKIFAVGGQN GLGGLDNVEY YDIKLNEWKM VSPMPWKGVT VKCAAVGSIV YVLAGFQGVG
       550        560        570        580
RLGHILEYNT ETDKWVANSK VRAFPVTSCL ICVVDTCGAN EETLET         10         20         30         40         50         60
MAASGVEKSS KKKTEKKLAA REEAKLLAGF MGVMNNMRKQ KTLCDVILMV QERKIPAHRV
        70         80         90        100        110        120
VLAAASHFFN LMFTTNMLES KSFEVELKDA EPDIIEQLVE FAYTARISVN SNNVQSLLDA
       130        140        150        160        170        180
ANQYQIEPVK KMCVDFLKEQ VDASNCLGIS VLAECLDCPE LKATADDFIH QHFTEVYKTD
       190        200        210        220        230        240
EFLQLDVKRV THLLNQDTLT VRAEDQVYDA AVRWLKYDEP NRQPFMVDIL AKVRFPLISK
       250        260        270        280        290        300
NFLSKTVQAE PLIQDNPECL KMVISGMRYH LLSPEDREEL VDGTRPRRKK HDYRIALFGG
       310        320        330        340        350        360
SQPQSCRYFN PKDYSWTDIR CPFEKRRDAA CVFWDNVVYI LGGSQLFPIK RMDCYNVVKD
       370        380        390        400        410        420
SWYSKLGPPT PRDSLAACAA EGKIYTSGGS EVGNSALYLF ECYDTRTESW HTKPSMLTQR
       430        440        450        460        470        480
CSHGMVEANG LIYVCGGSLG NNVSGRVLNS CEVYDPATET WTELCPMIEA RKNHGLVFVK
       490        500        510        520        530        540
DKIFAVGGQN GLGGLDNVEY YDIKLNEWKM VSPMPWKGVT VKCAAVGSIV YVLAGFQGVG
       550        560        570        580
RLGHILEYNT ETDKWVANSK VRAFPVTSCL ICVVDTCGAN EETLET         10         20         30         40         50         60
MAASGVEKSS KKKTEKKLAA REEAKLLAGF MGVMNNMRKQ KTLCDVILMV QERKIPAHRV
        70         80         90        100        110        120
VLAAASHFFN LMFTTNMLES KSFEVELKDA EPDIIEQLVE FAYTARISVN SNNVQSLLDA
       130        140        150        160        170        180
ANQYQIEPVK KMCVDFLKEQ VDASNCLGIS VLAECLDCPE LKATADDFIH QHFTEVYKTD
       190        200        210        220        230        240
EFLQLDVKRV THLLNQDTLT VRAEDQVYDA AVRWLKYDEP NRQPFMVDIL AKVRFPLISK
       250        260        270        280        290        300
NFLSKTVQAE PLIQDNPECL KMVISGMRYH LLSPEDREEL VDGTRPRRKK HDYRIALFGG
       310        320        330        340        350        360
SQPQSCRYFN PKDYSWTDIR CPFEKRRDAA CVFWDNVVYI LGGSQLFPIK RMDCYNVVKD
       370        380        390        400        410        420
SWYSKLGPPT PRDSLAACAA EGKIYTSGGS EVGNSALYLF ECYDTRTESW HTKPSMLTQR
       430        440        450        460        470        480
CSHGMVEANG LIYVCGGSLG NNVSGRVLNS CEVYDPATET WTELCPMIEA RKNHGLVFVK
       490        500        510        520        530        540
DKIFAVGGQN GLGGLDNVEY YDIKLNEWKM VSPMPWKGVT VKCAAVGSIV YVLAGFQGVG
       550        560        570        580
RLGHILEYNT ETDKWVANSK VRAFPVTSCL ICVVDTCGAN EETLET         10         20         30         40         50         60
MAASGVEKSS KKKTEKKLAA REEAKLLAGF MGVMNNMRKQ KTLCDVILMV QERKIPAHRV
        70         80         90        100        110        120
VLAAASHFFN LMFTTNMLES KSFEVELKDA EPDIIEQLVE FAYTARISVN SNNVQSLLDA
       130        140        150        160        170        180
ANQYQIEPVK KMCVDFLKEQ VDASNCLGIS VLAECLDCPE LKATADDFIH QHFTEVYKTD
       190        200        210        220        230        240
EFLQLDVKRV THLLNQDTLT VRAEDQVYDA AVRWLKYDEP NRQPFMVDIL AKVRFPLISK
       250        260        270        280        290        300
NFLSKTVQAE PLIQDNPECL KMVISGMRYH LLSPEDREEL VDGTRPRRKK HDYRIALFGG
       310        320        330        340        350        360
SQPQSCRYFN PKDYSWTDIR CPFEKRRDAA CVFWDNVVYI LGGSQLFPIK RMDCYNVVKD
       370        380        390        400        410        420
SWYSKLGPPT PRDSLAACAA EGKIYTSGGS EVGNSALYLF ECYDTRTESW HTKPSMLTQR
       430        440        450        460        470        480
CSHGMVEANG LIYVCGGSLG NNVSGRVLNS CEVYDPATET WTELCPMIEA RKNHGLVFVK
       490        500        510        520        530        540
DKIFAVGGQN GLGGLDNVEY YDIKLNEWKM VSPMPWKGVT VKCAAVGSIV YVLAGFQGVG
       550        560        570        580
RLGHILEYNT ETDKWVANSK VRAFPVTSCL ICVVDTCGAN EETLET

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8IXQ5-1-unknown	MAASGV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8IXQ5-1-unknown	MAASGV...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt79130
Q8IXQ5-2-acetylation	AASGVE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q8IXQ5-2-acetylation	AASGVE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q8IXQ5-2-acetylation	AASGVE...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162687
Q8IXQ5-49-unknown	MVQERK...	49		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt79132
Q8IXQ5-49-unknown	MVQERK...	49		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt97506
Q8IXQ5-49-unknown	MVQERK...	49		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt97508
Q8IXQ5-49-unknown	MVQERK...	49		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt97507

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ETLET	586	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ETLET	586	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74750
...ETLET	586	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74747

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)