Q8IYB8: ATP-dependent RNA helicase SUPV3L1, mitochondrial

General Information

Protein names	- ATP-dependent RNA helicase SUPV3L1, mitochondrial - 3.6.4.13 {ECO:0000269\|PubMed:12466530} - Suppressor of var1 3-like protein 1 - SUV3-like protein 1
Gene names	SUPV3L1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8IYB8

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSFSRALLWA RLPAGRQAGH RAAICSALRP HFGPFPGVLG QVSVLATASS SASGGSKIPN
        70         80         90        100        110        120
TSLFVPLTVK PQGPSADGDV GAELTRPLDK NEVKKVLDKF YKRKEIQKLG ADYGLDARLF
       130        140        150        160        170        180
HQAFISFRNY IMQSHSLDVD IHIVLNDICF GAAHADDLFP FFLRHAKQIF PVLDCKDDLR
       190        200        210        220        230        240
KISDLRIPPN WYPDARAMQR KIIFHSGPTN SGKTYHAIQK YFSAKSGVYC GPLKLLAHEI
       250        260        270        280        290        300
FEKSNAAGVP CDLVTGEERV TVQPNGKQAS HVSCTVEMCS VTTPYEVAVI DEIQMIRDPA
       310        320        330        340        350        360
RGWAWTRALL GLCAEEVHLC GEPAAIDLVM ELMYTTGEEV EVRDYKRLTP ISVLDHALES
       370        380        390        400        410        420
LDNLRPGDCI VCFSKNDIYS VSRQIEIRGL ESAVIYGSLP PGTKLAQAKK FNDPNDPCKI
       430        440        450        460        470        480
LVATDAIGMG LNLSIRRIIF YSLIKPSINE KGERELEPIT TSQALQIAGR AGRFSSRFKE
       490        500        510        520        530        540
GEVTTMNHED LSLLKEILKR PVDPIRAAGL HPTAEQIEMF AYHLPDATLS NLIDIFVDFS
       550        560        570        580        590        600
QVDGQYFVCN MDDFKFSAEL IQHIPLSLRV RYVFCTAPIN KKQPFVCSSL LQFARQYSRN
       610        620        630        640        650        660
EPLTFAWLRR YIKWPLLPPK NIKDLMDLEA VHDVLDLYLW LSYRFMDMFP DASLIRDLQK
       670        680        690        700        710        720
ELDGIIQDGV HNITKLIKMS ETHKLLNLEG FPSGSQSRLS GTLKSQARRT RGTKALGSKA
       730        740        750        760        770        780
TEPPSPDAGE LSLASRLVQQ GLLTPDMLKQ LEKEWMTQQT EHNKEKTESG THPKGTRRKK

KEPDSD

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8IYB8-23-unknown	AICSAL...	23	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8IYB8-46-unknown	ATASSS...	46		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q8IYB8-46-	ATASSS...	46		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q8IYB8-46-	ATASSS...	46		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q8IYB8-46-	ATASSS...	46		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q8IYB8-46-	ATASSS...	46		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...ERELEP	457	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000409072
...EPDSD	786	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EPDSD	786		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EPDSD	786		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...EPDSD	786		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EPDSD	786		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)