TopFIND 4.0

Q8IYI0: Shieldin complex subunit 1 {ECO:0000312|HGNC:HGNC:26318}

General Information

Protein names
- Shieldin complex subunit 1 {ECO:0000312|HGNC:HGNC:26318}
- RINN1-REV7-interacting novel NHEJ regulator 3 {ECO:0000303|PubMed:29656893}
- Shield complex subunit 1
Gene names C20orf196
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IYI0

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAARDATSGS LSEESSALDL PSACDIRDYV LQGPSQEANS EAFSSLEFHS FPYSSDVDPD 
        70         80         90        100        110        120 
TSNLNIEQNN SWTAENFWLD PAVKGQSEKE EDDGLRKSLD RFYEMFGHPQ PGSANSLSAS 
       130        140        150        160        170        180 
VCKCLSQKIT QLRGQESQKY ALRSFQMARV IFNRDGCSVL QRHSRDTHFY PLEEGSTSLD 
       190        200    
DEKPNPGLSK DITHFLLQQN VMKDL

Isoforms

- Isoform 2 of Uncharacterized protein C20orf196 - Isoform 2 of Shieldin complex subunit 1

Sequence View

        10         20         30         40         50         60 
MAARDATSGS LSEESSALDL PSACDIRDYV LQGPSQEANS EAFSSLEFHS FPYSSDVDPD 
        70         80         90        100        110        120 
TSNLNIEQNN SWTAENFWLD PAVKGQSEKE EDDGLRKSLD RFYEMFGHPQ PGSANSLSAS 
       130        140        150        160        170        180 
VCKCLSQKIT QLRGQESQKY ALRSFQMARV IFNRDGCSVL QRHSRDTHFY PLEEGSTSLD 
       190        200    
DEKPNPGLSK DITHFLLQQN VMKDL         10         20         30         40         50         60 
MAARDATSGS LSEESSALDL PSACDIRDYV LQGPSQEANS EAFSSLEFHS FPYSSDVDPD 
        70         80         90        100        110        120 
TSNLNIEQNN SWTAENFWLD PAVKGQSEKE EDDGLRKSLD RFYEMFGHPQ PGSANSLSAS 
       130        140        150        160        170        180 
VCKCLSQKIT QLRGQESQKY ALRSFQMARV IFNRDGCSVL QRHSRDTHFY PLEEGSTSLD 
       190        200    
DEKPNPGLSK DITHFLLQQN VMKDL



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IYI0-1-unknown MAARDA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IYI0-1-unknown MAARDA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71968

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VMKDL 205 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)