TopFIND 4.0

Q8IYM9: E3 ubiquitin-protein ligase TRIM22

General Information

Protein names
- E3 ubiquitin-protein ligase TRIM22
- 2.3.2.27
- 50 kDa-stimulated trans-acting factor
- RING finger protein 94
- RING-type E3 ubiquitin transferase TRIM22 {ECO:0000305}
- Staf-50
- Tripartite motif-containing protein 22
Gene names TRIM22
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IYM9

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDFSVKVDIE KEVTCPICLE LLTEPLSLDC GHSFCQACIT AKIKESVIIS RGESSCPVCQ 
        70         80         90        100        110        120 
TRFQPGNLRP NRHLANIVER VKEVKMSPQE GQKRDVCEHH GKKLQIFCKE DGKVICWVCE 
       130        140        150        160        170        180 
LSQEHQGHQT FRINEVVKEC QEKLQVALQR LIKEDQEAEK LEDDIRQERT AWKNYIQIER 
       190        200        210        220        230        240 
QKILKGFNEM RVILDNEEQR ELQKLEEGEV NVLDNLAAAT DQLVQQRQDA STLISDLQRR 
       250        260        270        280        290        300 
LRGSSVEMLQ DVIDVMKRSE SWTLKKPKSV SKKLKSVFRV PDLSGMLQVL KELTDVQYYW 
       310        320        330        340        350        360 
VDVMLNPGSA TSNVAISVDQ RQVKTVRTCT FKNSNPCDFS AFGVFGCQYF SSGKYYWEVD 
       370        380        390        400        410        420 
VSGKIAWILG VHSKISSLNK RKSSGFAFDP SVNYSKVYSR YRPQYGYWVI GLQNTCEYNA 
       430        440        450        460        470        480 
FEDSSSSDPK VLTLFMAVPP CRIGVFLDYE AGIVSFFNVT NHGALIYKFS GCRFSRPAYP 
       490    
YFNPWNCLVP MTVCPPSS

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase TRIM22

Sequence View

        10         20         30         40         50         60 
MDFSVKVDIE KEVTCPICLE LLTEPLSLDC GHSFCQACIT AKIKESVIIS RGESSCPVCQ 
        70         80         90        100        110        120 
TRFQPGNLRP NRHLANIVER VKEVKMSPQE GQKRDVCEHH GKKLQIFCKE DGKVICWVCE 
       130        140        150        160        170        180 
LSQEHQGHQT FRINEVVKEC QEKLQVALQR LIKEDQEAEK LEDDIRQERT AWKNYIQIER 
       190        200        210        220        230        240 
QKILKGFNEM RVILDNEEQR ELQKLEEGEV NVLDNLAAAT DQLVQQRQDA STLISDLQRR 
       250        260        270        280        290        300 
LRGSSVEMLQ DVIDVMKRSE SWTLKKPKSV SKKLKSVFRV PDLSGMLQVL KELTDVQYYW 
       310        320        330        340        350        360 
VDVMLNPGSA TSNVAISVDQ RQVKTVRTCT FKNSNPCDFS AFGVFGCQYF SSGKYYWEVD 
       370        380        390        400        410        420 
VSGKIAWILG VHSKISSLNK RKSSGFAFDP SVNYSKVYSR YRPQYGYWVI GLQNTCEYNA 
       430        440        450        460        470        480 
FEDSSSSDPK VLTLFMAVPP CRIGVFLDYE AGIVSFFNVT NHGALIYKFS GCRFSRPAYP 
       490    
YFNPWNCLVP MTVCPPSS



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IYM9-1-unknown MDFSVK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IYM9-1-unknown MDFSVK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93004

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CPPSS 498 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...CPPSS 498 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt88622

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)