Q8IYW2: Cilia- and flagella-associated protein 46 {ECO:0000305}
| Protein names | - Cilia- and flagella-associated protein 46 {ECO:0000305} - Tetratricopeptide repeat protein 40 {ECO:0000312|HGNC:HGNC:25247} |
|---|---|
| Gene names | TTC40 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q8IYW2 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDLVITQELA RAESQQDAAS LKKAYELIKS ANLGKSEFDP SESFSPDLFV LCAEQALKMR
70 80 90 100 110 120
QPEVSEDCIQ MYFKVKAPIT QFLGRAHLCR AQMCAPKSAE NLEEFENCVT EYMKAINFAK
130 140 150 160 170 180
GEPRYYFLVY NASVLYWQMV RPFLKPGYRH HLIPSLSQII NVLSQTEEED KEWRAELMLE
190 200 210 220 230 240
LLECYLQAGR KEEAARFCST AAPFIKSHVP QKYRQIFSVM VRHELMDELQ LKEEKKNSIS
250 260 270 280 290 300
LSVTFYINML KAKAEQNDLP GDISVILRKA YRHLGHYNHQ RFPSISEEKM LLLFELARFS
310 320 330 340 350 360
LTLKCMEISS ACLSDLKKME SKDPGKLIEM ECLECESEAL RLESKMKVYN RAAVEAQLDI
370 380 390 400 410 420
IQRLDVALQR AVRLGDPRVI HVVCATQWNT CLPLLQHNLR HHLRKPLAGV ADVLEKLDSL
430 440 450 460 470 480
MTLLRCQVHM EMAQIEEDED RLEPATEHLR KAARLDSLGL YRDRIQMAST RLRLCTTLYQ
490 500 510 520 530 540
APERAEDKAI MAVEQAKKAT PKDSVRKKRA LLVNAGLALA PDAFQIVLDS ENEAKVSTGK
550 560 570 580 590 600
NRGRFTYLCA KAWHHTVSVD KAAGHLRRLG NENDKERIQI WAELAKVARK QGVWDVCRTA
610 620 630 640 650 660
SRFCLLYDNV KVKKLRLRRG KKKRGRDGSV QDTWSQPEVV LQRQVCPDLL RKFAEVGFIH
670 680 690 700 710 720
AEATVHLLRS EGVELNDRAI PPEDLSQHPA GYVPEPPEVN AEWITYRTWI ESLSRCAMNN
730 740 750 760 770 780
WLRSAEIGQE IQEAWIVQNA VVYVLNHNHH LILAGRQKEL VDALYHLLSI VKATGHSGDP
790 800 810 820 830 840
VMLVTLCNTL ARGLIISWIP VQAAEKSRKF MRPNAFHSPL DAGATSEIKT AVEVCEFALN
850 860 870 880 890 900
LTNGSAPEET VPTGTRQQLI ATWVKAKQLL QQQIGPRLGT EEQGTNEDVS SVTRVLVALE
910 920 930 940 950 960
MYSCNGLGLM DFTVPSLAQL VKMASECNWS DPLVELQTLT RLTHFAHAAR DHETTMACAH
970 980 990 1000 1010 1020
RALEMGIKYL KKFGPEESRL VAEMLCTATA IQGRSIMENL KGRKQLRLVA AKAFTESARF
1030 1040 1050 1060 1070 1080
GGIAGSSALV MLAARHYWNA WLPLLSSAVY RKKAKGALKR LIGIINKTEA RKQEKGKTLL
1090 1100 1110 1120 1130 1140
LHQWPTADFQ GGGTTEGYFL PGAEDDLALR AALYGLLFHS HADQDDWEGG LKVLDEAVQV
1150 1160 1170 1180 1190 1200
LPRTAHRLLI FKHMVIVKAK LGQNFSMEIQ KFKAESEDYL ARMWHRLALN SPSVSGELAC
1210 1220 1230 1240 1250 1260
YNNAIQALQK PEMEWQKVEY LMEFGQWLHH RHFPLEDVVF HLRWAVEILL AMKPPGDVPE
1270 1280 1290 1300 1310 1320
PQPTPDGEYV AVEMPPRSPV SEAEEAVSLE QLRSVRQLEA LARVHILLAL VLSPGAEGYE
1330 1340 1350 1360 1370 1380
DCCLAAYAFF RHIWQVSLMT AGKSVLENRP LAATSSHLLL PKKEKENERS KEKEKERSKE
1390 1400 1410 1420 1430 1440
KENERSKEKD KEKGKEEKVK EPKQSQSPAP IKQLEDLPMS IEEWASYSCP EEVLSVLKQD
1450 1460 1470 1480 1490 1500
RSDSTVNPSS IQKPTYSLYF LDHLVKALQK MCLHELTVPV LQLGVLISDS VVGSKGLSDL
1510 1520 1530 1540 1550 1560
YHLRLAHACS ELKLREAAAR HEEAVGQVCV SELEQASCRK EIALKKEKNK EPLLEESLPA
1570 1580 1590 1600 1610 1620
LNEQTLPVQP GEIKPLDAKD KILKMNGETG RDLDGTSFPH LWMLKAEVLL EMNLYQPARL
1630 1640 1650 1660 1670 1680
LLSEAYLAFQ ELDEPCAEAQ CLLLLAQLAN KEKNYGQAKK MIAQAQHLGG SEEFWYNSTL
1690 1700 1710 1720 1730 1740
TLAEALLSME HSGREATVCH IFQKLINAFK ILKKERPNRL PLLEFMITDL EARCLSLRVR
1750 1760 1770 1780 1790 1800
VAQHSAVTEP TECSLLLKEM DDGLLEIERK FIDCGCKENC VDVKLERAKI KRLRAQNEKD
1810 1820 1830 1840 1850 1860
EEQKTAYYLE AYGLAQGAVA EEEGRLHSIQ GLYGLAQGAM AEEEGRLHSV QGLLSLQDLQ
1870 1880 1890 1900 1910 1920
NVNTPLMRKL ARLKLGLVEM ALDMLQFIWE EAHGQQSEQG SLEKLLADYL QNTSDYTSVG
1930 1940 1950 1960 1970 1980
LQWFTLKRTL AHGALAQLGS LQPLSVGCVE IRARLLGLAG RALHLLAMQA DPVHPTCYWE
1990 2000 2010 2020 2030 2040
AGPSVGAKLS GLKSLELEVE EEGATKSSRD PPASRAAPEE HCRRGEDLKR RMVLAQQYLA
2050 2060 2070 2080 2090 2100
QASEVLLQCL QVALGSGLLD VAAAASLEMV ECVGTLDPAT TCQFLALSQS CSASETMRDV
2110 2120 2130 2140 2150 2160
LLAATANTSS SQLAALLQLQ HQLRCQDRTT TSLGARVEQR LAAVSKAWQN LCVTEQHFNL
2170 2180 2190 2200 2210 2220
LNEMPPTFWI LFLHLSGDRS RLYGAAYEKP KFITAAKGKV QAVGGSCKVM RLAISPTAFS
2230 2240 2250 2260 2270 2280
HLLACAQQFR KQTQAQVYSE DMALNIGSEP EGLQVEEKER PVQRLSSVLG PLEELLQPLF
2290 2300 2310 2320 2330 2340
PLLSLSKARV QTPAVVADSG KSKGKDKERK TSTGQHSTVQ PEVADKIVLV ADRHLLELPL
2350 2360 2370 2380 2390 2400
EGLSVFDEGT ISSVSREFSL QMLWNRLHKE ETEGGVKKEG RSRDPKKRSL AKKGRKGSIP
2410 2420 2430 2440 2450 2460
RTIPPDCIIV DSDNFKFVVD PYEEAQGPEM LTPVSITQDI LERFQDTFTS RWAGHLGSKH
2470 2480 2490 2500 2510 2520
FPSQAQWEQA LGSCSGFFFY GMESFLSHIL VERLVAMNLQ ECQVAVLLDL ARSYQSLKRH
2530 2540 2550 2560 2570 2580
MESVEHRRSV GRWEANWRNS ASPSEDEWRR GGEPRRGFSD LEGQAAAAPK LRAPSHHAQL
2590 2600 2610 2620 2630 2640
GPVWAAAPSH RVVQAWTCLP SAAGAPALAS ALGSAPLPTH PHLPAPIPSS QLALPFLGLS
2650 2660 2670 2680 2690 2700
PALGAASARD PPPATSRKAA AWTSSSACLC APWGLRRGWS CVSSRGQDKG GLPLAALVLS
2710
CLDQKTIQTV SLFLI
Isoforms
- Isoform 2 of Tetratricopeptide repeat protein 40 - Isoform 3 of Tetratricopeptide repeat protein 40 - Isoform 2 of Cilia- and flagella-associated protein 46 - Isoform 3 of Cilia- and flagella-associated protein 46Sequence View
10 20 30 40 50 60
MDLVITQELA RAESQQDAAS LKKAYELIKS ANLGKSEFDP SESFSPDLFV LCAEQALKMR
70 80 90 100 110 120
QPEVSEDCIQ MYFKVKAPIT QFLGRAHLCR AQMCAPKSAE NLEEFENCVT EYMKAINFAK
130 140 150 160 170 180
GEPRYYFLVY NASVLYWQMV RPFLKPGYRH HLIPSLSQII NVLSQTEEED KEWRAELMLE
190 200 210 220 230 240
LLECYLQAGR KEEAARFCST AAPFIKSHVP QKYRQIFSVM VRHELMDELQ LKEEKKNSIS
250 260 270 280 290 300
LSVTFYINML KAKAEQNDLP GDISVILRKA YRHLGHYNHQ RFPSISEEKM LLLFELARFS
310 320 330 340 350 360
LTLKCMEISS ACLSDLKKME SKDPGKLIEM ECLECESEAL RLESKMKVYN RAAVEAQLDI
370 380 390 400 410 420
IQRLDVALQR AVRLGDPRVI HVVCATQWNT CLPLLQHNLR HHLRKPLAGV ADVLEKLDSL
430 440 450 460 470 480
MTLLRCQVHM EMAQIEEDED RLEPATEHLR KAARLDSLGL YRDRIQMAST RLRLCTTLYQ
490 500 510 520 530 540
APERAEDKAI MAVEQAKKAT PKDSVRKKRA LLVNAGLALA PDAFQIVLDS ENEAKVSTGK
550 560 570 580 590 600
NRGRFTYLCA KAWHHTVSVD KAAGHLRRLG NENDKERIQI WAELAKVARK QGVWDVCRTA
610 620 630 640 650 660
SRFCLLYDNV KVKKLRLRRG KKKRGRDGSV QDTWSQPEVV LQRQVCPDLL RKFAEVGFIH
670 680 690 700 710 720
AEATVHLLRS EGVELNDRAI PPEDLSQHPA GYVPEPPEVN AEWITYRTWI ESLSRCAMNN
730 740 750 760 770 780
WLRSAEIGQE IQEAWIVQNA VVYVLNHNHH LILAGRQKEL VDALYHLLSI VKATGHSGDP
790 800 810 820 830 840
VMLVTLCNTL ARGLIISWIP VQAAEKSRKF MRPNAFHSPL DAGATSEIKT AVEVCEFALN
850 860 870 880 890 900
LTNGSAPEET VPTGTRQQLI ATWVKAKQLL QQQIGPRLGT EEQGTNEDVS SVTRVLVALE
910 920 930 940 950 960
MYSCNGLGLM DFTVPSLAQL VKMASECNWS DPLVELQTLT RLTHFAHAAR DHETTMACAH
970 980 990 1000 1010 1020
RALEMGIKYL KKFGPEESRL VAEMLCTATA IQGRSIMENL KGRKQLRLVA AKAFTESARF
1030 1040 1050 1060 1070 1080
GGIAGSSALV MLAARHYWNA WLPLLSSAVY RKKAKGALKR LIGIINKTEA RKQEKGKTLL
1090 1100 1110 1120 1130 1140
LHQWPTADFQ GGGTTEGYFL PGAEDDLALR AALYGLLFHS HADQDDWEGG LKVLDEAVQV
1150 1160 1170 1180 1190 1200
LPRTAHRLLI FKHMVIVKAK LGQNFSMEIQ KFKAESEDYL ARMWHRLALN SPSVSGELAC
1210 1220 1230 1240 1250 1260
YNNAIQALQK PEMEWQKVEY LMEFGQWLHH RHFPLEDVVF HLRWAVEILL AMKPPGDVPE
1270 1280 1290 1300 1310 1320
PQPTPDGEYV AVEMPPRSPV SEAEEAVSLE QLRSVRQLEA LARVHILLAL VLSPGAEGYE
1330 1340 1350 1360 1370 1380
DCCLAAYAFF RHIWQVSLMT AGKSVLENRP LAATSSHLLL PKKEKENERS KEKEKERSKE
1390 1400 1410 1420 1430 1440
KENERSKEKD KEKGKEEKVK EPKQSQSPAP IKQLEDLPMS IEEWASYSCP EEVLSVLKQD
1450 1460 1470 1480 1490 1500
RSDSTVNPSS IQKPTYSLYF LDHLVKALQK MCLHELTVPV LQLGVLISDS VVGSKGLSDL
1510 1520 1530 1540 1550 1560
YHLRLAHACS ELKLREAAAR HEEAVGQVCV SELEQASCRK EIALKKEKNK EPLLEESLPA
1570 1580 1590 1600 1610 1620
LNEQTLPVQP GEIKPLDAKD KILKMNGETG RDLDGTSFPH LWMLKAEVLL EMNLYQPARL
1630 1640 1650 1660 1670 1680
LLSEAYLAFQ ELDEPCAEAQ CLLLLAQLAN KEKNYGQAKK MIAQAQHLGG SEEFWYNSTL
1690 1700 1710 1720 1730 1740
TLAEALLSME HSGREATVCH IFQKLINAFK ILKKERPNRL PLLEFMITDL EARCLSLRVR
1750 1760 1770 1780 1790 1800
VAQHSAVTEP TECSLLLKEM DDGLLEIERK FIDCGCKENC VDVKLERAKI KRLRAQNEKD
1810 1820 1830 1840 1850 1860
EEQKTAYYLE AYGLAQGAVA EEEGRLHSIQ GLYGLAQGAM AEEEGRLHSV QGLLSLQDLQ
1870 1880 1890 1900 1910 1920
NVNTPLMRKL ARLKLGLVEM ALDMLQFIWE EAHGQQSEQG SLEKLLADYL QNTSDYTSVG
1930 1940 1950 1960 1970 1980
LQWFTLKRTL AHGALAQLGS LQPLSVGCVE IRARLLGLAG RALHLLAMQA DPVHPTCYWE
1990 2000 2010 2020 2030 2040
AGPSVGAKLS GLKSLELEVE EEGATKSSRD PPASRAAPEE HCRRGEDLKR RMVLAQQYLA
2050 2060 2070 2080 2090 2100
QASEVLLQCL QVALGSGLLD VAAAASLEMV ECVGTLDPAT TCQFLALSQS CSASETMRDV
2110 2120 2130 2140 2150 2160
LLAATANTSS SQLAALLQLQ HQLRCQDRTT TSLGARVEQR LAAVSKAWQN LCVTEQHFNL
2170 2180 2190 2200 2210 2220
LNEMPPTFWI LFLHLSGDRS RLYGAAYEKP KFITAAKGKV QAVGGSCKVM RLAISPTAFS
2230 2240 2250 2260 2270 2280
HLLACAQQFR KQTQAQVYSE DMALNIGSEP EGLQVEEKER PVQRLSSVLG PLEELLQPLF
2290 2300 2310 2320 2330 2340
PLLSLSKARV QTPAVVADSG KSKGKDKERK TSTGQHSTVQ PEVADKIVLV ADRHLLELPL
2350 2360 2370 2380 2390 2400
EGLSVFDEGT ISSVSREFSL QMLWNRLHKE ETEGGVKKEG RSRDPKKRSL AKKGRKGSIP
2410 2420 2430 2440 2450 2460
RTIPPDCIIV DSDNFKFVVD PYEEAQGPEM LTPVSITQDI LERFQDTFTS RWAGHLGSKH
2470 2480 2490 2500 2510 2520
FPSQAQWEQA LGSCSGFFFY GMESFLSHIL VERLVAMNLQ ECQVAVLLDL ARSYQSLKRH
2530 2540 2550 2560 2570 2580
MESVEHRRSV GRWEANWRNS ASPSEDEWRR GGEPRRGFSD LEGQAAAAPK LRAPSHHAQL
2590 2600 2610 2620 2630 2640
GPVWAAAPSH RVVQAWTCLP SAAGAPALAS ALGSAPLPTH PHLPAPIPSS QLALPFLGLS
2650 2660 2670 2680 2690 2700
PALGAASARD PPPATSRKAA AWTSSSACLC APWGLRRGWS CVSSRGQDKG GLPLAALVLS
2710
CLDQKTIQTV SLFLI
10 20 30 40 50 60
MDLVITQELA RAESQQDAAS LKKAYELIKS ANLGKSEFDP SESFSPDLFV LCAEQALKMR
70 80 90 100 110 120
QPEVSEDCIQ MYFKVKAPIT QFLGRAHLCR AQMCAPKSAE NLEEFENCVT EYMKAINFAK
130 140 150 160 170 180
GEPRYYFLVY NASVLYWQMV RPFLKPGYRH HLIPSLSQII NVLSQTEEED KEWRAELMLE
190 200 210 220 230 240
LLECYLQAGR KEEAARFCST AAPFIKSHVP QKYRQIFSVM VRHELMDELQ LKEEKKNSIS
250 260 270 280 290 300
LSVTFYINML KAKAEQNDLP GDISVILRKA YRHLGHYNHQ RFPSISEEKM LLLFELARFS
310 320 330 340 350 360
LTLKCMEISS ACLSDLKKME SKDPGKLIEM ECLECESEAL RLESKMKVYN RAAVEAQLDI
370 380 390 400 410 420
IQRLDVALQR AVRLGDPRVI HVVCATQWNT CLPLLQHNLR HHLRKPLAGV ADVLEKLDSL
430 440 450 460 470 480
MTLLRCQVHM EMAQIEEDED RLEPATEHLR KAARLDSLGL YRDRIQMAST RLRLCTTLYQ
490 500 510 520 530 540
APERAEDKAI MAVEQAKKAT PKDSVRKKRA LLVNAGLALA PDAFQIVLDS ENEAKVSTGK
550 560 570 580 590 600
NRGRFTYLCA KAWHHTVSVD KAAGHLRRLG NENDKERIQI WAELAKVARK QGVWDVCRTA
610 620 630 640 650 660
SRFCLLYDNV KVKKLRLRRG KKKRGRDGSV QDTWSQPEVV LQRQVCPDLL RKFAEVGFIH
670 680 690 700 710 720
AEATVHLLRS EGVELNDRAI PPEDLSQHPA GYVPEPPEVN AEWITYRTWI ESLSRCAMNN
730 740 750 760 770 780
WLRSAEIGQE IQEAWIVQNA VVYVLNHNHH LILAGRQKEL VDALYHLLSI VKATGHSGDP
790 800 810 820 830 840
VMLVTLCNTL ARGLIISWIP VQAAEKSRKF MRPNAFHSPL DAGATSEIKT AVEVCEFALN
850 860 870 880 890 900
LTNGSAPEET VPTGTRQQLI ATWVKAKQLL QQQIGPRLGT EEQGTNEDVS SVTRVLVALE
910 920 930 940 950 960
MYSCNGLGLM DFTVPSLAQL VKMASECNWS DPLVELQTLT RLTHFAHAAR DHETTMACAH
970 980 990 1000 1010 1020
RALEMGIKYL KKFGPEESRL VAEMLCTATA IQGRSIMENL KGRKQLRLVA AKAFTESARF
1030 1040 1050 1060 1070 1080
GGIAGSSALV MLAARHYWNA WLPLLSSAVY RKKAKGALKR LIGIINKTEA RKQEKGKTLL
1090 1100 1110 1120 1130 1140
LHQWPTADFQ GGGTTEGYFL PGAEDDLALR AALYGLLFHS HADQDDWEGG LKVLDEAVQV
1150 1160 1170 1180 1190 1200
LPRTAHRLLI FKHMVIVKAK LGQNFSMEIQ KFKAESEDYL ARMWHRLALN SPSVSGELAC
1210 1220 1230 1240 1250 1260
YNNAIQALQK PEMEWQKVEY LMEFGQWLHH RHFPLEDVVF HLRWAVEILL AMKPPGDVPE
1270 1280 1290 1300 1310 1320
PQPTPDGEYV AVEMPPRSPV SEAEEAVSLE QLRSVRQLEA LARVHILLAL VLSPGAEGYE
1330 1340 1350 1360 1370 1380
DCCLAAYAFF RHIWQVSLMT AGKSVLENRP LAATSSHLLL PKKEKENERS KEKEKERSKE
1390 1400 1410 1420 1430 1440
KENERSKEKD KEKGKEEKVK EPKQSQSPAP IKQLEDLPMS IEEWASYSCP EEVLSVLKQD
1450 1460 1470 1480 1490 1500
RSDSTVNPSS IQKPTYSLYF LDHLVKALQK MCLHELTVPV LQLGVLISDS VVGSKGLSDL
1510 1520 1530 1540 1550 1560
YHLRLAHACS ELKLREAAAR HEEAVGQVCV SELEQASCRK EIALKKEKNK EPLLEESLPA
1570 1580 1590 1600 1610 1620
LNEQTLPVQP GEIKPLDAKD KILKMNGETG RDLDGTSFPH LWMLKAEVLL EMNLYQPARL
1630 1640 1650 1660 1670 1680
LLSEAYLAFQ ELDEPCAEAQ CLLLLAQLAN KEKNYGQAKK MIAQAQHLGG SEEFWYNSTL
1690 1700 1710 1720 1730 1740
TLAEALLSME HSGREATVCH IFQKLINAFK ILKKERPNRL PLLEFMITDL EARCLSLRVR
1750 1760 1770 1780 1790 1800
VAQHSAVTEP TECSLLLKEM DDGLLEIERK FIDCGCKENC VDVKLERAKI KRLRAQNEKD
1810 1820 1830 1840 1850 1860
EEQKTAYYLE AYGLAQGAVA EEEGRLHSIQ GLYGLAQGAM AEEEGRLHSV QGLLSLQDLQ
1870 1880 1890 1900 1910 1920
NVNTPLMRKL ARLKLGLVEM ALDMLQFIWE EAHGQQSEQG SLEKLLADYL QNTSDYTSVG
1930 1940 1950 1960 1970 1980
LQWFTLKRTL AHGALAQLGS LQPLSVGCVE IRARLLGLAG RALHLLAMQA DPVHPTCYWE
1990 2000 2010 2020 2030 2040
AGPSVGAKLS GLKSLELEVE EEGATKSSRD PPASRAAPEE HCRRGEDLKR RMVLAQQYLA
2050 2060 2070 2080 2090 2100
QASEVLLQCL QVALGSGLLD VAAAASLEMV ECVGTLDPAT TCQFLALSQS CSASETMRDV
2110 2120 2130 2140 2150 2160
LLAATANTSS SQLAALLQLQ HQLRCQDRTT TSLGARVEQR LAAVSKAWQN LCVTEQHFNL
2170 2180 2190 2200 2210 2220
LNEMPPTFWI LFLHLSGDRS RLYGAAYEKP KFITAAKGKV QAVGGSCKVM RLAISPTAFS
2230 2240 2250 2260 2270 2280
HLLACAQQFR KQTQAQVYSE DMALNIGSEP EGLQVEEKER PVQRLSSVLG PLEELLQPLF
2290 2300 2310 2320 2330 2340
PLLSLSKARV QTPAVVADSG KSKGKDKERK TSTGQHSTVQ PEVADKIVLV ADRHLLELPL
2350 2360 2370 2380 2390 2400
EGLSVFDEGT ISSVSREFSL QMLWNRLHKE ETEGGVKKEG RSRDPKKRSL AKKGRKGSIP
2410 2420 2430 2440 2450 2460
RTIPPDCIIV DSDNFKFVVD PYEEAQGPEM LTPVSITQDI LERFQDTFTS RWAGHLGSKH
2470 2480 2490 2500 2510 2520
FPSQAQWEQA LGSCSGFFFY GMESFLSHIL VERLVAMNLQ ECQVAVLLDL ARSYQSLKRH
2530 2540 2550 2560 2570 2580
MESVEHRRSV GRWEANWRNS ASPSEDEWRR GGEPRRGFSD LEGQAAAAPK LRAPSHHAQL
2590 2600 2610 2620 2630 2640
GPVWAAAPSH RVVQAWTCLP SAAGAPALAS ALGSAPLPTH PHLPAPIPSS QLALPFLGLS
2650 2660 2670 2680 2690 2700
PALGAASARD PPPATSRKAA AWTSSSACLC APWGLRRGWS CVSSRGQDKG GLPLAALVLS
2710
CLDQKTIQTV SLFLI
10 20 30 40 50 60
MDLVITQELA RAESQQDAAS LKKAYELIKS ANLGKSEFDP SESFSPDLFV LCAEQALKMR
70 80 90 100 110 120
QPEVSEDCIQ MYFKVKAPIT QFLGRAHLCR AQMCAPKSAE NLEEFENCVT EYMKAINFAK
130 140 150 160 170 180
GEPRYYFLVY NASVLYWQMV RPFLKPGYRH HLIPSLSQII NVLSQTEEED KEWRAELMLE
190 200 210 220 230 240
LLECYLQAGR KEEAARFCST AAPFIKSHVP QKYRQIFSVM VRHELMDELQ LKEEKKNSIS
250 260 270 280 290 300
LSVTFYINML KAKAEQNDLP GDISVILRKA YRHLGHYNHQ RFPSISEEKM LLLFELARFS
310 320 330 340 350 360
LTLKCMEISS ACLSDLKKME SKDPGKLIEM ECLECESEAL RLESKMKVYN RAAVEAQLDI
370 380 390 400 410 420
IQRLDVALQR AVRLGDPRVI HVVCATQWNT CLPLLQHNLR HHLRKPLAGV ADVLEKLDSL
430 440 450 460 470 480
MTLLRCQVHM EMAQIEEDED RLEPATEHLR KAARLDSLGL YRDRIQMAST RLRLCTTLYQ
490 500 510 520 530 540
APERAEDKAI MAVEQAKKAT PKDSVRKKRA LLVNAGLALA PDAFQIVLDS ENEAKVSTGK
550 560 570 580 590 600
NRGRFTYLCA KAWHHTVSVD KAAGHLRRLG NENDKERIQI WAELAKVARK QGVWDVCRTA
610 620 630 640 650 660
SRFCLLYDNV KVKKLRLRRG KKKRGRDGSV QDTWSQPEVV LQRQVCPDLL RKFAEVGFIH
670 680 690 700 710 720
AEATVHLLRS EGVELNDRAI PPEDLSQHPA GYVPEPPEVN AEWITYRTWI ESLSRCAMNN
730 740 750 760 770 780
WLRSAEIGQE IQEAWIVQNA VVYVLNHNHH LILAGRQKEL VDALYHLLSI VKATGHSGDP
790 800 810 820 830 840
VMLVTLCNTL ARGLIISWIP VQAAEKSRKF MRPNAFHSPL DAGATSEIKT AVEVCEFALN
850 860 870 880 890 900
LTNGSAPEET VPTGTRQQLI ATWVKAKQLL QQQIGPRLGT EEQGTNEDVS SVTRVLVALE
910 920 930 940 950 960
MYSCNGLGLM DFTVPSLAQL VKMASECNWS DPLVELQTLT RLTHFAHAAR DHETTMACAH
970 980 990 1000 1010 1020
RALEMGIKYL KKFGPEESRL VAEMLCTATA IQGRSIMENL KGRKQLRLVA AKAFTESARF
1030 1040 1050 1060 1070 1080
GGIAGSSALV MLAARHYWNA WLPLLSSAVY RKKAKGALKR LIGIINKTEA RKQEKGKTLL
1090 1100 1110 1120 1130 1140
LHQWPTADFQ GGGTTEGYFL PGAEDDLALR AALYGLLFHS HADQDDWEGG LKVLDEAVQV
1150 1160 1170 1180 1190 1200
LPRTAHRLLI FKHMVIVKAK LGQNFSMEIQ KFKAESEDYL ARMWHRLALN SPSVSGELAC
1210 1220 1230 1240 1250 1260
YNNAIQALQK PEMEWQKVEY LMEFGQWLHH RHFPLEDVVF HLRWAVEILL AMKPPGDVPE
1270 1280 1290 1300 1310 1320
PQPTPDGEYV AVEMPPRSPV SEAEEAVSLE QLRSVRQLEA LARVHILLAL VLSPGAEGYE
1330 1340 1350 1360 1370 1380
DCCLAAYAFF RHIWQVSLMT AGKSVLENRP LAATSSHLLL PKKEKENERS KEKEKERSKE
1390 1400 1410 1420 1430 1440
KENERSKEKD KEKGKEEKVK EPKQSQSPAP IKQLEDLPMS IEEWASYSCP EEVLSVLKQD
1450 1460 1470 1480 1490 1500
RSDSTVNPSS IQKPTYSLYF LDHLVKALQK MCLHELTVPV LQLGVLISDS VVGSKGLSDL
1510 1520 1530 1540 1550 1560
YHLRLAHACS ELKLREAAAR HEEAVGQVCV SELEQASCRK EIALKKEKNK EPLLEESLPA
1570 1580 1590 1600 1610 1620
LNEQTLPVQP GEIKPLDAKD KILKMNGETG RDLDGTSFPH LWMLKAEVLL EMNLYQPARL
1630 1640 1650 1660 1670 1680
LLSEAYLAFQ ELDEPCAEAQ CLLLLAQLAN KEKNYGQAKK MIAQAQHLGG SEEFWYNSTL
1690 1700 1710 1720 1730 1740
TLAEALLSME HSGREATVCH IFQKLINAFK ILKKERPNRL PLLEFMITDL EARCLSLRVR
1750 1760 1770 1780 1790 1800
VAQHSAVTEP TECSLLLKEM DDGLLEIERK FIDCGCKENC VDVKLERAKI KRLRAQNEKD
1810 1820 1830 1840 1850 1860
EEQKTAYYLE AYGLAQGAVA EEEGRLHSIQ GLYGLAQGAM AEEEGRLHSV QGLLSLQDLQ
1870 1880 1890 1900 1910 1920
NVNTPLMRKL ARLKLGLVEM ALDMLQFIWE EAHGQQSEQG SLEKLLADYL QNTSDYTSVG
1930 1940 1950 1960 1970 1980
LQWFTLKRTL AHGALAQLGS LQPLSVGCVE IRARLLGLAG RALHLLAMQA DPVHPTCYWE
1990 2000 2010 2020 2030 2040
AGPSVGAKLS GLKSLELEVE EEGATKSSRD PPASRAAPEE HCRRGEDLKR RMVLAQQYLA
2050 2060 2070 2080 2090 2100
QASEVLLQCL QVALGSGLLD VAAAASLEMV ECVGTLDPAT TCQFLALSQS CSASETMRDV
2110 2120 2130 2140 2150 2160
LLAATANTSS SQLAALLQLQ HQLRCQDRTT TSLGARVEQR LAAVSKAWQN LCVTEQHFNL
2170 2180 2190 2200 2210 2220
LNEMPPTFWI LFLHLSGDRS RLYGAAYEKP KFITAAKGKV QAVGGSCKVM RLAISPTAFS
2230 2240 2250 2260 2270 2280
HLLACAQQFR KQTQAQVYSE DMALNIGSEP EGLQVEEKER PVQRLSSVLG PLEELLQPLF
2290 2300 2310 2320 2330 2340
PLLSLSKARV QTPAVVADSG KSKGKDKERK TSTGQHSTVQ PEVADKIVLV ADRHLLELPL
2350 2360 2370 2380 2390 2400
EGLSVFDEGT ISSVSREFSL QMLWNRLHKE ETEGGVKKEG RSRDPKKRSL AKKGRKGSIP
2410 2420 2430 2440 2450 2460
RTIPPDCIIV DSDNFKFVVD PYEEAQGPEM LTPVSITQDI LERFQDTFTS RWAGHLGSKH
2470 2480 2490 2500 2510 2520
FPSQAQWEQA LGSCSGFFFY GMESFLSHIL VERLVAMNLQ ECQVAVLLDL ARSYQSLKRH
2530 2540 2550 2560 2570 2580
MESVEHRRSV GRWEANWRNS ASPSEDEWRR GGEPRRGFSD LEGQAAAAPK LRAPSHHAQL
2590 2600 2610 2620 2630 2640
GPVWAAAPSH RVVQAWTCLP SAAGAPALAS ALGSAPLPTH PHLPAPIPSS QLALPFLGLS
2650 2660 2670 2680 2690 2700
PALGAASARD PPPATSRKAA AWTSSSACLC APWGLRRGWS CVSSRGQDKG GLPLAALVLS
2710
CLDQKTIQTV SLFLI
10 20 30 40 50 60
MDLVITQELA RAESQQDAAS LKKAYELIKS ANLGKSEFDP SESFSPDLFV LCAEQALKMR
70 80 90 100 110 120
QPEVSEDCIQ MYFKVKAPIT QFLGRAHLCR AQMCAPKSAE NLEEFENCVT EYMKAINFAK
130 140 150 160 170 180
GEPRYYFLVY NASVLYWQMV RPFLKPGYRH HLIPSLSQII NVLSQTEEED KEWRAELMLE
190 200 210 220 230 240
LLECYLQAGR KEEAARFCST AAPFIKSHVP QKYRQIFSVM VRHELMDELQ LKEEKKNSIS
250 260 270 280 290 300
LSVTFYINML KAKAEQNDLP GDISVILRKA YRHLGHYNHQ RFPSISEEKM LLLFELARFS
310 320 330 340 350 360
LTLKCMEISS ACLSDLKKME SKDPGKLIEM ECLECESEAL RLESKMKVYN RAAVEAQLDI
370 380 390 400 410 420
IQRLDVALQR AVRLGDPRVI HVVCATQWNT CLPLLQHNLR HHLRKPLAGV ADVLEKLDSL
430 440 450 460 470 480
MTLLRCQVHM EMAQIEEDED RLEPATEHLR KAARLDSLGL YRDRIQMAST RLRLCTTLYQ
490 500 510 520 530 540
APERAEDKAI MAVEQAKKAT PKDSVRKKRA LLVNAGLALA PDAFQIVLDS ENEAKVSTGK
550 560 570 580 590 600
NRGRFTYLCA KAWHHTVSVD KAAGHLRRLG NENDKERIQI WAELAKVARK QGVWDVCRTA
610 620 630 640 650 660
SRFCLLYDNV KVKKLRLRRG KKKRGRDGSV QDTWSQPEVV LQRQVCPDLL RKFAEVGFIH
670 680 690 700 710 720
AEATVHLLRS EGVELNDRAI PPEDLSQHPA GYVPEPPEVN AEWITYRTWI ESLSRCAMNN
730 740 750 760 770 780
WLRSAEIGQE IQEAWIVQNA VVYVLNHNHH LILAGRQKEL VDALYHLLSI VKATGHSGDP
790 800 810 820 830 840
VMLVTLCNTL ARGLIISWIP VQAAEKSRKF MRPNAFHSPL DAGATSEIKT AVEVCEFALN
850 860 870 880 890 900
LTNGSAPEET VPTGTRQQLI ATWVKAKQLL QQQIGPRLGT EEQGTNEDVS SVTRVLVALE
910 920 930 940 950 960
MYSCNGLGLM DFTVPSLAQL VKMASECNWS DPLVELQTLT RLTHFAHAAR DHETTMACAH
970 980 990 1000 1010 1020
RALEMGIKYL KKFGPEESRL VAEMLCTATA IQGRSIMENL KGRKQLRLVA AKAFTESARF
1030 1040 1050 1060 1070 1080
GGIAGSSALV MLAARHYWNA WLPLLSSAVY RKKAKGALKR LIGIINKTEA RKQEKGKTLL
1090 1100 1110 1120 1130 1140
LHQWPTADFQ GGGTTEGYFL PGAEDDLALR AALYGLLFHS HADQDDWEGG LKVLDEAVQV
1150 1160 1170 1180 1190 1200
LPRTAHRLLI FKHMVIVKAK LGQNFSMEIQ KFKAESEDYL ARMWHRLALN SPSVSGELAC
1210 1220 1230 1240 1250 1260
YNNAIQALQK PEMEWQKVEY LMEFGQWLHH RHFPLEDVVF HLRWAVEILL AMKPPGDVPE
1270 1280 1290 1300 1310 1320
PQPTPDGEYV AVEMPPRSPV SEAEEAVSLE QLRSVRQLEA LARVHILLAL VLSPGAEGYE
1330 1340 1350 1360 1370 1380
DCCLAAYAFF RHIWQVSLMT AGKSVLENRP LAATSSHLLL PKKEKENERS KEKEKERSKE
1390 1400 1410 1420 1430 1440
KENERSKEKD KEKGKEEKVK EPKQSQSPAP IKQLEDLPMS IEEWASYSCP EEVLSVLKQD
1450 1460 1470 1480 1490 1500
RSDSTVNPSS IQKPTYSLYF LDHLVKALQK MCLHELTVPV LQLGVLISDS VVGSKGLSDL
1510 1520 1530 1540 1550 1560
YHLRLAHACS ELKLREAAAR HEEAVGQVCV SELEQASCRK EIALKKEKNK EPLLEESLPA
1570 1580 1590 1600 1610 1620
LNEQTLPVQP GEIKPLDAKD KILKMNGETG RDLDGTSFPH LWMLKAEVLL EMNLYQPARL
1630 1640 1650 1660 1670 1680
LLSEAYLAFQ ELDEPCAEAQ CLLLLAQLAN KEKNYGQAKK MIAQAQHLGG SEEFWYNSTL
1690 1700 1710 1720 1730 1740
TLAEALLSME HSGREATVCH IFQKLINAFK ILKKERPNRL PLLEFMITDL EARCLSLRVR
1750 1760 1770 1780 1790 1800
VAQHSAVTEP TECSLLLKEM DDGLLEIERK FIDCGCKENC VDVKLERAKI KRLRAQNEKD
1810 1820 1830 1840 1850 1860
EEQKTAYYLE AYGLAQGAVA EEEGRLHSIQ GLYGLAQGAM AEEEGRLHSV QGLLSLQDLQ
1870 1880 1890 1900 1910 1920
NVNTPLMRKL ARLKLGLVEM ALDMLQFIWE EAHGQQSEQG SLEKLLADYL QNTSDYTSVG
1930 1940 1950 1960 1970 1980
LQWFTLKRTL AHGALAQLGS LQPLSVGCVE IRARLLGLAG RALHLLAMQA DPVHPTCYWE
1990 2000 2010 2020 2030 2040
AGPSVGAKLS GLKSLELEVE EEGATKSSRD PPASRAAPEE HCRRGEDLKR RMVLAQQYLA
2050 2060 2070 2080 2090 2100
QASEVLLQCL QVALGSGLLD VAAAASLEMV ECVGTLDPAT TCQFLALSQS CSASETMRDV
2110 2120 2130 2140 2150 2160
LLAATANTSS SQLAALLQLQ HQLRCQDRTT TSLGARVEQR LAAVSKAWQN LCVTEQHFNL
2170 2180 2190 2200 2210 2220
LNEMPPTFWI LFLHLSGDRS RLYGAAYEKP KFITAAKGKV QAVGGSCKVM RLAISPTAFS
2230 2240 2250 2260 2270 2280
HLLACAQQFR KQTQAQVYSE DMALNIGSEP EGLQVEEKER PVQRLSSVLG PLEELLQPLF
2290 2300 2310 2320 2330 2340
PLLSLSKARV QTPAVVADSG KSKGKDKERK TSTGQHSTVQ PEVADKIVLV ADRHLLELPL
2350 2360 2370 2380 2390 2400
EGLSVFDEGT ISSVSREFSL QMLWNRLHKE ETEGGVKKEG RSRDPKKRSL AKKGRKGSIP
2410 2420 2430 2440 2450 2460
RTIPPDCIIV DSDNFKFVVD PYEEAQGPEM LTPVSITQDI LERFQDTFTS RWAGHLGSKH
2470 2480 2490 2500 2510 2520
FPSQAQWEQA LGSCSGFFFY GMESFLSHIL VERLVAMNLQ ECQVAVLLDL ARSYQSLKRH
2530 2540 2550 2560 2570 2580
MESVEHRRSV GRWEANWRNS ASPSEDEWRR GGEPRRGFSD LEGQAAAAPK LRAPSHHAQL
2590 2600 2610 2620 2630 2640
GPVWAAAPSH RVVQAWTCLP SAAGAPALAS ALGSAPLPTH PHLPAPIPSS QLALPFLGLS
2650 2660 2670 2680 2690 2700
PALGAASARD PPPATSRKAA AWTSSSACLC APWGLRRGWS CVSSRGQDKG GLPLAALVLS
2710
CLDQKTIQTV SLFLI
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q8IYW2-1-unknown | MDLVIT... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q8IYW2-1-unknown | MDLVIT... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93372 | |||
| Q8IYW2-1-unknown | MDLVIT... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93373 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...SLFLI | 2715 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|