Q8IZF6: Adhesion G-protein coupled receptor G4 {ECO:0000303|PubMed:25713288}
| Protein names | - Adhesion G-protein coupled receptor G4 {ECO:0000303|PubMed:25713288} - G-protein coupled receptor 112 |
|---|---|
| Gene names | GPR112 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | S63.017 |
| Chromosome location | |
| UniProt ID | Q8IZF6 |
3
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MKEHIIYQKL YGLILMSSFI FLSDTLSLKG KKLDFFGRGD TYVSLIDTIP ELSRFTACID
70 80 90 100 110 120
LVFMDDNSRY WMAFSYITNN ALLGREDIDL GLAGDHQQLI LYRLGKTFSI RHHLASFQWH
130 140 150 160 170 180
TICLIWDGVK GKLELFLNKE RILEVTDQPH NLTPHGTLFL GHFLKNESSE VKSMMRSFPG
190 200 210 220 230 240
SLYYFQLWDH ILENEEFMKC LDGNIVSWEE DVWLVNKIIP TVDRTLRCFV PENMTIQEKS
250 260 270 280 290 300
TTVSQQIDMT TPSQITGVKP QNTAHSSTLL SQSIPIFATD YTTISYSNTT SPPLETMTAQ
310 320 330 340 350 360
KILKTLVDET ATFAVDVLST SSAISLPTQS ISIDNTTNSM KKTKSPSSES TKTTKMVEAM
370 380 390 400 410 420
ATEIFQPPTP SNFLSTSRFT KNSVVSTTSA IKSQSAVTKT TSLFSTIEST SMSTTPCLKQ
430 440 450 460 470 480
KSTNTGALPI STAGQEFIES TAAGTVPWFT VEKTSPASTH VGTASSFPPE PVLISTAAPV
490 500 510 520 530 540
DSVFPRNQTA FPLATTDMKI AFTVHSLTLP TRLIETTPAP RTAETELTST NFQDVSLPRV
550 560 570 580 590 600
EDAMSTSMSK ETSSKTFSFL TSFSFTGTES VQTVIDAEAT RTALTPEITL ASTVAETMLS
610 620 630 640 650 660
STITGRVYTQ NTPTADGHLL TLMSTRSAST SKAPESGPTS TTDEAAHLFS SNETIWTSRP
670 680 690 700 710 720
DQALLASMNT TTILTFVPNE NFTSAFHENT TYTEYLSATT NITPLKASPE GKGTTANDAT
730 740 750 760 770 780
TARYTTAVSK LTSPWFANFS IVSGTTSITN MPEFKLTTLL LKTIPMSTKP ANELPLTPRE
790 800 810 820 830 840
TVVPSVDIIS TLACIQPNFS TEESASETTQ TEINGAIVFG GTTTPVPKSA TTQRLNATVT
850 860 870 880 890 900
RKEATSHYLM RKSTIAAVAE VSPFSTMLEV TDESAQRVTA SVTVSSFPDI EKLSTPLDNK
910 920 930 940 950 960
TATTEVRESW LLTKLVKTTP RSSYNEMTEM FNFNHTYVAH WTSETSEGIS AGSPTSGSTH
970 980 990 1000 1010 1020
IFGEPLGAST TRISETSFST TPTDRTATSL SDGILPPQPT AAHSSATPVP VTHMFSLPVN
1030 1040 1050 1060 1070 1080
GSSVVAEETE VTMSEPSTLA RAFSTSVLSD VSNLSSTTMT TALVPPLDQT ASTTIVIVPT
1090 1100 1110 1120 1130 1140
HGDLIRTTSE ATVISVRKTS MAVPSLTETP FHSLRLSTPV TAKAETTLFS TSVDTVTPST
1150 1160 1170 1180 1190 1200
HTLVCSKPPP DNIPPASSTH VISTTSTPEA TQPISQVEET STYALSFPYT FSGGGVVASL
1210 1220 1230 1240 1250 1260
ATGTTETSVV DETTPSHISA NKLTTSVNSH ISSSATYRVH TPVSIQLVTS TSVLSSDKDQ
1270 1280 1290 1300 1310 1320
MTISLGKTPR TMEVTEMSPS KNSFISYSRG TPSLEMTDTG FPETTKISSH QTHSPSEIPL
1330 1340 1350 1360 1370 1380
GTPSDGNLAS SPTSGSTQIT PTLTSSNTVG VHIPEMSTSL GKTALPSQAL TITTFLCPEK
1390 1400 1410 1420 1430 1440
ESTSALPAYT PRTVEMIVNS TYVTHSVSYG QDTSFVDTTT SSSTRISNPM DINTTFSHLH
1450 1460 1470 1480 1490 1500
SLRTQPEVTS VASFISESTQ TFPESLSLST AGLYNDGFTV LSDRITTAFS VPNVPTMLPR
1510 1520 1530 1540 1550 1560
ESSMATSTPI YQMSSLPVNV TAFTSKKVSD TPPIVITKSS KTMHPGCLKS PCTATSGPMS
1570 1580 1590 1600 1610 1620
EMSSIPVNNS AFTPATVSSD TSTRVGLFST LLSSVTPRTT MTMQTSTLDV TPVIYAGATS
1630 1640 1650 1660 1670 1680
KNKMVSSAFT TEMIEAPSRI TPTTFLSPTE PTLPFVKTVP TTIMAGIVTP FVGTTAFSPL
1690 1700 1710 1720 1730 1740
SSKSTGAISS IPKTTFSPFL SATQQSSQAD EATTLGILSG ITNRSLSTVN SGTGVALTDT
1750 1760 1770 1780 1790 1800
YSRITVPENM LSPTHADSLH TSFNIQVSPS LTSFKSASGP TKNVKTTTNC FSSNTRKMTS
1810 1820 1830 1840 1850 1860
LLEKTSLTNY ATSLNTPVSY PPWTPSSATL PSLTSFVYSP HSTEAEISTP KTSPPPTSQM
1870 1880 1890 1900 1910 1920
VEFPVLGTRM TSSNTQPLLM TSWNIPTAEG SQFPISTTIN VPTSNEMETE TLHLVPGPLS
1930 1940 1950 1960 1970 1980
TFTASQTGLV SKDVMAMSSI PMSGILPNHG LSENPSLSTS LRAITSTLAD VKHTFEKMTT
1990 2000 2010 2020 2030 2040
SVTPGTTLPS ILSGATSGSV ISKSPILTWL LSSLPSGSPP ATVSNAPHVM TSSTVEVSKS
2050 2060 2070 2080 2090 2100
TFLTSDMISA HPFTNLTTLP SATMSTILTR TIPTPTLGGI TTGFPTSLPM SINVTDDIVY
2110 2120 2130 2140 2150 2160
ISTHPEASSR TTITANPRTV SHPSSFSRKT MSPSTTDHTL SVGAMPLPSS TITSSWNRIP
2170 2180 2190 2200 2210 2220
TASSPSTLII PKPTLDSLLN IMTTTSTVPG ASFPLISTGV TYPFTATVSS PISSFFETTW
2230 2240 2250 2260 2270 2280
LDSTPSFLST EASTSPTATK STVSFYNVEM SFSVFVEEPR IPITSVINEF TENSLNSIFQ
2290 2300 2310 2320 2330 2340
NSEFSLATLE TQIKSRDISE EEMVMDRAIL EQREGQEMAT ISYVPYSCVC QVIIKASSSL
2350 2360 2370 2380 2390 2400
ASSELMRKIK SKIHGNFTHG NFTQDQLTLL VNCEHVAVKK LEPGNCKADE TASKYKGTYK
2410 2420 2430 2440 2450 2460
WLLTNPTETA QTRCIKNEDG NATRFCSISI NTGKSQWEKP KFKQCKLLQE LPDKIVDLAN
2470 2480 2490 2500 2510 2520
ITISDENAED VAEHILNLIN ESPALGKEET KIIVSKISDI SQCDEISMNL THVMLQIINV
2530 2540 2550 2560 2570 2580
VLEKQNNSAS DLHEISNEIL RIIERTGHKM EFSGQIANLT VAGLALAVLR GDHTFDGMAF
2590 2600 2610 2620 2630 2640
SIHSYEEGTD PEIFLGNVPV GGILASIYLP KSLTERIPLS NLQTILFNFF GQTSLFKTKN
2650 2660 2670 2680 2690 2700
VTKALTTYVV SASISDDMFI QNLADPVVIT LQHIGGNQNY GQVHCAFWDF ENNNGLGGWN
2710 2720 2730 2740 2750 2760
SSGCKVKETN VNYTICQCDH LTHFGVLMDL SRSTVDSVNE QILALITYTG CGISSIFLGV
2770 2780 2790 2800 2810 2820
AVVTYIAFHK LRKDYPAKIL INLCTALLML NLVFLINSWL SSFQKVGVCI TAAVALHYFL
2830 2840 2850 2860 2870 2880
LVSFTWMGLE AVHMYLALVK VFNIYIPNYI LKFCLVGWGI PAIMVAITVS VKKDLYGTLS
2890 2900 2910 2920 2930 2940
PTTPFCWIKD DSIFYISVVA YFCLIFLMNL SMFCTVLVQL NSVKSQIQKT RRKMILHDLK
2950 2960 2970 2980 2990 3000
GTMSLTFLLG LTWGFAFFAW GPMRNFFLYL FAIFNTLQGF FIFVFHCVMK ESVREQWQIH
3010 3020 3030 3040 3050 3060
LCCGWLRLDN SSDGSSRCQI KVGYKQEGLK KIFEHKLLTP SLKSTATSST FKSLGSAQGT
3070 3080
PSEISFPNDD FDKDPYCSSP
Isoforms
- Isoform 2 of Probable G-protein coupled receptor 112 - Isoform 3 of Probable G-protein coupled receptor 112 - Isoform 2 of Adhesion G-protein coupled receptor G4 - Isoform 3 of Adhesion G-protein coupled receptor G4Sequence View
10 20 30 40 50 60
MKEHIIYQKL YGLILMSSFI FLSDTLSLKG KKLDFFGRGD TYVSLIDTIP ELSRFTACID
70 80 90 100 110 120
LVFMDDNSRY WMAFSYITNN ALLGREDIDL GLAGDHQQLI LYRLGKTFSI RHHLASFQWH
130 140 150 160 170 180
TICLIWDGVK GKLELFLNKE RILEVTDQPH NLTPHGTLFL GHFLKNESSE VKSMMRSFPG
190 200 210 220 230 240
SLYYFQLWDH ILENEEFMKC LDGNIVSWEE DVWLVNKIIP TVDRTLRCFV PENMTIQEKS
250 260 270 280 290 300
TTVSQQIDMT TPSQITGVKP QNTAHSSTLL SQSIPIFATD YTTISYSNTT SPPLETMTAQ
310 320 330 340 350 360
KILKTLVDET ATFAVDVLST SSAISLPTQS ISIDNTTNSM KKTKSPSSES TKTTKMVEAM
370 380 390 400 410 420
ATEIFQPPTP SNFLSTSRFT KNSVVSTTSA IKSQSAVTKT TSLFSTIEST SMSTTPCLKQ
430 440 450 460 470 480
KSTNTGALPI STAGQEFIES TAAGTVPWFT VEKTSPASTH VGTASSFPPE PVLISTAAPV
490 500 510 520 530 540
DSVFPRNQTA FPLATTDMKI AFTVHSLTLP TRLIETTPAP RTAETELTST NFQDVSLPRV
550 560 570 580 590 600
EDAMSTSMSK ETSSKTFSFL TSFSFTGTES VQTVIDAEAT RTALTPEITL ASTVAETMLS
610 620 630 640 650 660
STITGRVYTQ NTPTADGHLL TLMSTRSAST SKAPESGPTS TTDEAAHLFS SNETIWTSRP
670 680 690 700 710 720
DQALLASMNT TTILTFVPNE NFTSAFHENT TYTEYLSATT NITPLKASPE GKGTTANDAT
730 740 750 760 770 780
TARYTTAVSK LTSPWFANFS IVSGTTSITN MPEFKLTTLL LKTIPMSTKP ANELPLTPRE
790 800 810 820 830 840
TVVPSVDIIS TLACIQPNFS TEESASETTQ TEINGAIVFG GTTTPVPKSA TTQRLNATVT
850 860 870 880 890 900
RKEATSHYLM RKSTIAAVAE VSPFSTMLEV TDESAQRVTA SVTVSSFPDI EKLSTPLDNK
910 920 930 940 950 960
TATTEVRESW LLTKLVKTTP RSSYNEMTEM FNFNHTYVAH WTSETSEGIS AGSPTSGSTH
970 980 990 1000 1010 1020
IFGEPLGAST TRISETSFST TPTDRTATSL SDGILPPQPT AAHSSATPVP VTHMFSLPVN
1030 1040 1050 1060 1070 1080
GSSVVAEETE VTMSEPSTLA RAFSTSVLSD VSNLSSTTMT TALVPPLDQT ASTTIVIVPT
1090 1100 1110 1120 1130 1140
HGDLIRTTSE ATVISVRKTS MAVPSLTETP FHSLRLSTPV TAKAETTLFS TSVDTVTPST
1150 1160 1170 1180 1190 1200
HTLVCSKPPP DNIPPASSTH VISTTSTPEA TQPISQVEET STYALSFPYT FSGGGVVASL
1210 1220 1230 1240 1250 1260
ATGTTETSVV DETTPSHISA NKLTTSVNSH ISSSATYRVH TPVSIQLVTS TSVLSSDKDQ
1270 1280 1290 1300 1310 1320
MTISLGKTPR TMEVTEMSPS KNSFISYSRG TPSLEMTDTG FPETTKISSH QTHSPSEIPL
1330 1340 1350 1360 1370 1380
GTPSDGNLAS SPTSGSTQIT PTLTSSNTVG VHIPEMSTSL GKTALPSQAL TITTFLCPEK
1390 1400 1410 1420 1430 1440
ESTSALPAYT PRTVEMIVNS TYVTHSVSYG QDTSFVDTTT SSSTRISNPM DINTTFSHLH
1450 1460 1470 1480 1490 1500
SLRTQPEVTS VASFISESTQ TFPESLSLST AGLYNDGFTV LSDRITTAFS VPNVPTMLPR
1510 1520 1530 1540 1550 1560
ESSMATSTPI YQMSSLPVNV TAFTSKKVSD TPPIVITKSS KTMHPGCLKS PCTATSGPMS
1570 1580 1590 1600 1610 1620
EMSSIPVNNS AFTPATVSSD TSTRVGLFST LLSSVTPRTT MTMQTSTLDV TPVIYAGATS
1630 1640 1650 1660 1670 1680
KNKMVSSAFT TEMIEAPSRI TPTTFLSPTE PTLPFVKTVP TTIMAGIVTP FVGTTAFSPL
1690 1700 1710 1720 1730 1740
SSKSTGAISS IPKTTFSPFL SATQQSSQAD EATTLGILSG ITNRSLSTVN SGTGVALTDT
1750 1760 1770 1780 1790 1800
YSRITVPENM LSPTHADSLH TSFNIQVSPS LTSFKSASGP TKNVKTTTNC FSSNTRKMTS
1810 1820 1830 1840 1850 1860
LLEKTSLTNY ATSLNTPVSY PPWTPSSATL PSLTSFVYSP HSTEAEISTP KTSPPPTSQM
1870 1880 1890 1900 1910 1920
VEFPVLGTRM TSSNTQPLLM TSWNIPTAEG SQFPISTTIN VPTSNEMETE TLHLVPGPLS
1930 1940 1950 1960 1970 1980
TFTASQTGLV SKDVMAMSSI PMSGILPNHG LSENPSLSTS LRAITSTLAD VKHTFEKMTT
1990 2000 2010 2020 2030 2040
SVTPGTTLPS ILSGATSGSV ISKSPILTWL LSSLPSGSPP ATVSNAPHVM TSSTVEVSKS
2050 2060 2070 2080 2090 2100
TFLTSDMISA HPFTNLTTLP SATMSTILTR TIPTPTLGGI TTGFPTSLPM SINVTDDIVY
2110 2120 2130 2140 2150 2160
ISTHPEASSR TTITANPRTV SHPSSFSRKT MSPSTTDHTL SVGAMPLPSS TITSSWNRIP
2170 2180 2190 2200 2210 2220
TASSPSTLII PKPTLDSLLN IMTTTSTVPG ASFPLISTGV TYPFTATVSS PISSFFETTW
2230 2240 2250 2260 2270 2280
LDSTPSFLST EASTSPTATK STVSFYNVEM SFSVFVEEPR IPITSVINEF TENSLNSIFQ
2290 2300 2310 2320 2330 2340
NSEFSLATLE TQIKSRDISE EEMVMDRAIL EQREGQEMAT ISYVPYSCVC QVIIKASSSL
2350 2360 2370 2380 2390 2400
ASSELMRKIK SKIHGNFTHG NFTQDQLTLL VNCEHVAVKK LEPGNCKADE TASKYKGTYK
2410 2420 2430 2440 2450 2460
WLLTNPTETA QTRCIKNEDG NATRFCSISI NTGKSQWEKP KFKQCKLLQE LPDKIVDLAN
2470 2480 2490 2500 2510 2520
ITISDENAED VAEHILNLIN ESPALGKEET KIIVSKISDI SQCDEISMNL THVMLQIINV
2530 2540 2550 2560 2570 2580
VLEKQNNSAS DLHEISNEIL RIIERTGHKM EFSGQIANLT VAGLALAVLR GDHTFDGMAF
2590 2600 2610 2620 2630 2640
SIHSYEEGTD PEIFLGNVPV GGILASIYLP KSLTERIPLS NLQTILFNFF GQTSLFKTKN
2650 2660 2670 2680 2690 2700
VTKALTTYVV SASISDDMFI QNLADPVVIT LQHIGGNQNY GQVHCAFWDF ENNNGLGGWN
2710 2720 2730 2740 2750 2760
SSGCKVKETN VNYTICQCDH LTHFGVLMDL SRSTVDSVNE QILALITYTG CGISSIFLGV
2770 2780 2790 2800 2810 2820
AVVTYIAFHK LRKDYPAKIL INLCTALLML NLVFLINSWL SSFQKVGVCI TAAVALHYFL
2830 2840 2850 2860 2870 2880
LVSFTWMGLE AVHMYLALVK VFNIYIPNYI LKFCLVGWGI PAIMVAITVS VKKDLYGTLS
2890 2900 2910 2920 2930 2940
PTTPFCWIKD DSIFYISVVA YFCLIFLMNL SMFCTVLVQL NSVKSQIQKT RRKMILHDLK
2950 2960 2970 2980 2990 3000
GTMSLTFLLG LTWGFAFFAW GPMRNFFLYL FAIFNTLQGF FIFVFHCVMK ESVREQWQIH
3010 3020 3030 3040 3050 3060
LCCGWLRLDN SSDGSSRCQI KVGYKQEGLK KIFEHKLLTP SLKSTATSST FKSLGSAQGT
3070 3080
PSEISFPNDD FDKDPYCSSP
10 20 30 40 50 60
MKEHIIYQKL YGLILMSSFI FLSDTLSLKG KKLDFFGRGD TYVSLIDTIP ELSRFTACID
70 80 90 100 110 120
LVFMDDNSRY WMAFSYITNN ALLGREDIDL GLAGDHQQLI LYRLGKTFSI RHHLASFQWH
130 140 150 160 170 180
TICLIWDGVK GKLELFLNKE RILEVTDQPH NLTPHGTLFL GHFLKNESSE VKSMMRSFPG
190 200 210 220 230 240
SLYYFQLWDH ILENEEFMKC LDGNIVSWEE DVWLVNKIIP TVDRTLRCFV PENMTIQEKS
250 260 270 280 290 300
TTVSQQIDMT TPSQITGVKP QNTAHSSTLL SQSIPIFATD YTTISYSNTT SPPLETMTAQ
310 320 330 340 350 360
KILKTLVDET ATFAVDVLST SSAISLPTQS ISIDNTTNSM KKTKSPSSES TKTTKMVEAM
370 380 390 400 410 420
ATEIFQPPTP SNFLSTSRFT KNSVVSTTSA IKSQSAVTKT TSLFSTIEST SMSTTPCLKQ
430 440 450 460 470 480
KSTNTGALPI STAGQEFIES TAAGTVPWFT VEKTSPASTH VGTASSFPPE PVLISTAAPV
490 500 510 520 530 540
DSVFPRNQTA FPLATTDMKI AFTVHSLTLP TRLIETTPAP RTAETELTST NFQDVSLPRV
550 560 570 580 590 600
EDAMSTSMSK ETSSKTFSFL TSFSFTGTES VQTVIDAEAT RTALTPEITL ASTVAETMLS
610 620 630 640 650 660
STITGRVYTQ NTPTADGHLL TLMSTRSAST SKAPESGPTS TTDEAAHLFS SNETIWTSRP
670 680 690 700 710 720
DQALLASMNT TTILTFVPNE NFTSAFHENT TYTEYLSATT NITPLKASPE GKGTTANDAT
730 740 750 760 770 780
TARYTTAVSK LTSPWFANFS IVSGTTSITN MPEFKLTTLL LKTIPMSTKP ANELPLTPRE
790 800 810 820 830 840
TVVPSVDIIS TLACIQPNFS TEESASETTQ TEINGAIVFG GTTTPVPKSA TTQRLNATVT
850 860 870 880 890 900
RKEATSHYLM RKSTIAAVAE VSPFSTMLEV TDESAQRVTA SVTVSSFPDI EKLSTPLDNK
910 920 930 940 950 960
TATTEVRESW LLTKLVKTTP RSSYNEMTEM FNFNHTYVAH WTSETSEGIS AGSPTSGSTH
970 980 990 1000 1010 1020
IFGEPLGAST TRISETSFST TPTDRTATSL SDGILPPQPT AAHSSATPVP VTHMFSLPVN
1030 1040 1050 1060 1070 1080
GSSVVAEETE VTMSEPSTLA RAFSTSVLSD VSNLSSTTMT TALVPPLDQT ASTTIVIVPT
1090 1100 1110 1120 1130 1140
HGDLIRTTSE ATVISVRKTS MAVPSLTETP FHSLRLSTPV TAKAETTLFS TSVDTVTPST
1150 1160 1170 1180 1190 1200
HTLVCSKPPP DNIPPASSTH VISTTSTPEA TQPISQVEET STYALSFPYT FSGGGVVASL
1210 1220 1230 1240 1250 1260
ATGTTETSVV DETTPSHISA NKLTTSVNSH ISSSATYRVH TPVSIQLVTS TSVLSSDKDQ
1270 1280 1290 1300 1310 1320
MTISLGKTPR TMEVTEMSPS KNSFISYSRG TPSLEMTDTG FPETTKISSH QTHSPSEIPL
1330 1340 1350 1360 1370 1380
GTPSDGNLAS SPTSGSTQIT PTLTSSNTVG VHIPEMSTSL GKTALPSQAL TITTFLCPEK
1390 1400 1410 1420 1430 1440
ESTSALPAYT PRTVEMIVNS TYVTHSVSYG QDTSFVDTTT SSSTRISNPM DINTTFSHLH
1450 1460 1470 1480 1490 1500
SLRTQPEVTS VASFISESTQ TFPESLSLST AGLYNDGFTV LSDRITTAFS VPNVPTMLPR
1510 1520 1530 1540 1550 1560
ESSMATSTPI YQMSSLPVNV TAFTSKKVSD TPPIVITKSS KTMHPGCLKS PCTATSGPMS
1570 1580 1590 1600 1610 1620
EMSSIPVNNS AFTPATVSSD TSTRVGLFST LLSSVTPRTT MTMQTSTLDV TPVIYAGATS
1630 1640 1650 1660 1670 1680
KNKMVSSAFT TEMIEAPSRI TPTTFLSPTE PTLPFVKTVP TTIMAGIVTP FVGTTAFSPL
1690 1700 1710 1720 1730 1740
SSKSTGAISS IPKTTFSPFL SATQQSSQAD EATTLGILSG ITNRSLSTVN SGTGVALTDT
1750 1760 1770 1780 1790 1800
YSRITVPENM LSPTHADSLH TSFNIQVSPS LTSFKSASGP TKNVKTTTNC FSSNTRKMTS
1810 1820 1830 1840 1850 1860
LLEKTSLTNY ATSLNTPVSY PPWTPSSATL PSLTSFVYSP HSTEAEISTP KTSPPPTSQM
1870 1880 1890 1900 1910 1920
VEFPVLGTRM TSSNTQPLLM TSWNIPTAEG SQFPISTTIN VPTSNEMETE TLHLVPGPLS
1930 1940 1950 1960 1970 1980
TFTASQTGLV SKDVMAMSSI PMSGILPNHG LSENPSLSTS LRAITSTLAD VKHTFEKMTT
1990 2000 2010 2020 2030 2040
SVTPGTTLPS ILSGATSGSV ISKSPILTWL LSSLPSGSPP ATVSNAPHVM TSSTVEVSKS
2050 2060 2070 2080 2090 2100
TFLTSDMISA HPFTNLTTLP SATMSTILTR TIPTPTLGGI TTGFPTSLPM SINVTDDIVY
2110 2120 2130 2140 2150 2160
ISTHPEASSR TTITANPRTV SHPSSFSRKT MSPSTTDHTL SVGAMPLPSS TITSSWNRIP
2170 2180 2190 2200 2210 2220
TASSPSTLII PKPTLDSLLN IMTTTSTVPG ASFPLISTGV TYPFTATVSS PISSFFETTW
2230 2240 2250 2260 2270 2280
LDSTPSFLST EASTSPTATK STVSFYNVEM SFSVFVEEPR IPITSVINEF TENSLNSIFQ
2290 2300 2310 2320 2330 2340
NSEFSLATLE TQIKSRDISE EEMVMDRAIL EQREGQEMAT ISYVPYSCVC QVIIKASSSL
2350 2360 2370 2380 2390 2400
ASSELMRKIK SKIHGNFTHG NFTQDQLTLL VNCEHVAVKK LEPGNCKADE TASKYKGTYK
2410 2420 2430 2440 2450 2460
WLLTNPTETA QTRCIKNEDG NATRFCSISI NTGKSQWEKP KFKQCKLLQE LPDKIVDLAN
2470 2480 2490 2500 2510 2520
ITISDENAED VAEHILNLIN ESPALGKEET KIIVSKISDI SQCDEISMNL THVMLQIINV
2530 2540 2550 2560 2570 2580
VLEKQNNSAS DLHEISNEIL RIIERTGHKM EFSGQIANLT VAGLALAVLR GDHTFDGMAF
2590 2600 2610 2620 2630 2640
SIHSYEEGTD PEIFLGNVPV GGILASIYLP KSLTERIPLS NLQTILFNFF GQTSLFKTKN
2650 2660 2670 2680 2690 2700
VTKALTTYVV SASISDDMFI QNLADPVVIT LQHIGGNQNY GQVHCAFWDF ENNNGLGGWN
2710 2720 2730 2740 2750 2760
SSGCKVKETN VNYTICQCDH LTHFGVLMDL SRSTVDSVNE QILALITYTG CGISSIFLGV
2770 2780 2790 2800 2810 2820
AVVTYIAFHK LRKDYPAKIL INLCTALLML NLVFLINSWL SSFQKVGVCI TAAVALHYFL
2830 2840 2850 2860 2870 2880
LVSFTWMGLE AVHMYLALVK VFNIYIPNYI LKFCLVGWGI PAIMVAITVS VKKDLYGTLS
2890 2900 2910 2920 2930 2940
PTTPFCWIKD DSIFYISVVA YFCLIFLMNL SMFCTVLVQL NSVKSQIQKT RRKMILHDLK
2950 2960 2970 2980 2990 3000
GTMSLTFLLG LTWGFAFFAW GPMRNFFLYL FAIFNTLQGF FIFVFHCVMK ESVREQWQIH
3010 3020 3030 3040 3050 3060
LCCGWLRLDN SSDGSSRCQI KVGYKQEGLK KIFEHKLLTP SLKSTATSST FKSLGSAQGT
3070 3080
PSEISFPNDD FDKDPYCSSP
10 20 30 40 50 60
MKEHIIYQKL YGLILMSSFI FLSDTLSLKG KKLDFFGRGD TYVSLIDTIP ELSRFTACID
70 80 90 100 110 120
LVFMDDNSRY WMAFSYITNN ALLGREDIDL GLAGDHQQLI LYRLGKTFSI RHHLASFQWH
130 140 150 160 170 180
TICLIWDGVK GKLELFLNKE RILEVTDQPH NLTPHGTLFL GHFLKNESSE VKSMMRSFPG
190 200 210 220 230 240
SLYYFQLWDH ILENEEFMKC LDGNIVSWEE DVWLVNKIIP TVDRTLRCFV PENMTIQEKS
250 260 270 280 290 300
TTVSQQIDMT TPSQITGVKP QNTAHSSTLL SQSIPIFATD YTTISYSNTT SPPLETMTAQ
310 320 330 340 350 360
KILKTLVDET ATFAVDVLST SSAISLPTQS ISIDNTTNSM KKTKSPSSES TKTTKMVEAM
370 380 390 400 410 420
ATEIFQPPTP SNFLSTSRFT KNSVVSTTSA IKSQSAVTKT TSLFSTIEST SMSTTPCLKQ
430 440 450 460 470 480
KSTNTGALPI STAGQEFIES TAAGTVPWFT VEKTSPASTH VGTASSFPPE PVLISTAAPV
490 500 510 520 530 540
DSVFPRNQTA FPLATTDMKI AFTVHSLTLP TRLIETTPAP RTAETELTST NFQDVSLPRV
550 560 570 580 590 600
EDAMSTSMSK ETSSKTFSFL TSFSFTGTES VQTVIDAEAT RTALTPEITL ASTVAETMLS
610 620 630 640 650 660
STITGRVYTQ NTPTADGHLL TLMSTRSAST SKAPESGPTS TTDEAAHLFS SNETIWTSRP
670 680 690 700 710 720
DQALLASMNT TTILTFVPNE NFTSAFHENT TYTEYLSATT NITPLKASPE GKGTTANDAT
730 740 750 760 770 780
TARYTTAVSK LTSPWFANFS IVSGTTSITN MPEFKLTTLL LKTIPMSTKP ANELPLTPRE
790 800 810 820 830 840
TVVPSVDIIS TLACIQPNFS TEESASETTQ TEINGAIVFG GTTTPVPKSA TTQRLNATVT
850 860 870 880 890 900
RKEATSHYLM RKSTIAAVAE VSPFSTMLEV TDESAQRVTA SVTVSSFPDI EKLSTPLDNK
910 920 930 940 950 960
TATTEVRESW LLTKLVKTTP RSSYNEMTEM FNFNHTYVAH WTSETSEGIS AGSPTSGSTH
970 980 990 1000 1010 1020
IFGEPLGAST TRISETSFST TPTDRTATSL SDGILPPQPT AAHSSATPVP VTHMFSLPVN
1030 1040 1050 1060 1070 1080
GSSVVAEETE VTMSEPSTLA RAFSTSVLSD VSNLSSTTMT TALVPPLDQT ASTTIVIVPT
1090 1100 1110 1120 1130 1140
HGDLIRTTSE ATVISVRKTS MAVPSLTETP FHSLRLSTPV TAKAETTLFS TSVDTVTPST
1150 1160 1170 1180 1190 1200
HTLVCSKPPP DNIPPASSTH VISTTSTPEA TQPISQVEET STYALSFPYT FSGGGVVASL
1210 1220 1230 1240 1250 1260
ATGTTETSVV DETTPSHISA NKLTTSVNSH ISSSATYRVH TPVSIQLVTS TSVLSSDKDQ
1270 1280 1290 1300 1310 1320
MTISLGKTPR TMEVTEMSPS KNSFISYSRG TPSLEMTDTG FPETTKISSH QTHSPSEIPL
1330 1340 1350 1360 1370 1380
GTPSDGNLAS SPTSGSTQIT PTLTSSNTVG VHIPEMSTSL GKTALPSQAL TITTFLCPEK
1390 1400 1410 1420 1430 1440
ESTSALPAYT PRTVEMIVNS TYVTHSVSYG QDTSFVDTTT SSSTRISNPM DINTTFSHLH
1450 1460 1470 1480 1490 1500
SLRTQPEVTS VASFISESTQ TFPESLSLST AGLYNDGFTV LSDRITTAFS VPNVPTMLPR
1510 1520 1530 1540 1550 1560
ESSMATSTPI YQMSSLPVNV TAFTSKKVSD TPPIVITKSS KTMHPGCLKS PCTATSGPMS
1570 1580 1590 1600 1610 1620
EMSSIPVNNS AFTPATVSSD TSTRVGLFST LLSSVTPRTT MTMQTSTLDV TPVIYAGATS
1630 1640 1650 1660 1670 1680
KNKMVSSAFT TEMIEAPSRI TPTTFLSPTE PTLPFVKTVP TTIMAGIVTP FVGTTAFSPL
1690 1700 1710 1720 1730 1740
SSKSTGAISS IPKTTFSPFL SATQQSSQAD EATTLGILSG ITNRSLSTVN SGTGVALTDT
1750 1760 1770 1780 1790 1800
YSRITVPENM LSPTHADSLH TSFNIQVSPS LTSFKSASGP TKNVKTTTNC FSSNTRKMTS
1810 1820 1830 1840 1850 1860
LLEKTSLTNY ATSLNTPVSY PPWTPSSATL PSLTSFVYSP HSTEAEISTP KTSPPPTSQM
1870 1880 1890 1900 1910 1920
VEFPVLGTRM TSSNTQPLLM TSWNIPTAEG SQFPISTTIN VPTSNEMETE TLHLVPGPLS
1930 1940 1950 1960 1970 1980
TFTASQTGLV SKDVMAMSSI PMSGILPNHG LSENPSLSTS LRAITSTLAD VKHTFEKMTT
1990 2000 2010 2020 2030 2040
SVTPGTTLPS ILSGATSGSV ISKSPILTWL LSSLPSGSPP ATVSNAPHVM TSSTVEVSKS
2050 2060 2070 2080 2090 2100
TFLTSDMISA HPFTNLTTLP SATMSTILTR TIPTPTLGGI TTGFPTSLPM SINVTDDIVY
2110 2120 2130 2140 2150 2160
ISTHPEASSR TTITANPRTV SHPSSFSRKT MSPSTTDHTL SVGAMPLPSS TITSSWNRIP
2170 2180 2190 2200 2210 2220
TASSPSTLII PKPTLDSLLN IMTTTSTVPG ASFPLISTGV TYPFTATVSS PISSFFETTW
2230 2240 2250 2260 2270 2280
LDSTPSFLST EASTSPTATK STVSFYNVEM SFSVFVEEPR IPITSVINEF TENSLNSIFQ
2290 2300 2310 2320 2330 2340
NSEFSLATLE TQIKSRDISE EEMVMDRAIL EQREGQEMAT ISYVPYSCVC QVIIKASSSL
2350 2360 2370 2380 2390 2400
ASSELMRKIK SKIHGNFTHG NFTQDQLTLL VNCEHVAVKK LEPGNCKADE TASKYKGTYK
2410 2420 2430 2440 2450 2460
WLLTNPTETA QTRCIKNEDG NATRFCSISI NTGKSQWEKP KFKQCKLLQE LPDKIVDLAN
2470 2480 2490 2500 2510 2520
ITISDENAED VAEHILNLIN ESPALGKEET KIIVSKISDI SQCDEISMNL THVMLQIINV
2530 2540 2550 2560 2570 2580
VLEKQNNSAS DLHEISNEIL RIIERTGHKM EFSGQIANLT VAGLALAVLR GDHTFDGMAF
2590 2600 2610 2620 2630 2640
SIHSYEEGTD PEIFLGNVPV GGILASIYLP KSLTERIPLS NLQTILFNFF GQTSLFKTKN
2650 2660 2670 2680 2690 2700
VTKALTTYVV SASISDDMFI QNLADPVVIT LQHIGGNQNY GQVHCAFWDF ENNNGLGGWN
2710 2720 2730 2740 2750 2760
SSGCKVKETN VNYTICQCDH LTHFGVLMDL SRSTVDSVNE QILALITYTG CGISSIFLGV
2770 2780 2790 2800 2810 2820
AVVTYIAFHK LRKDYPAKIL INLCTALLML NLVFLINSWL SSFQKVGVCI TAAVALHYFL
2830 2840 2850 2860 2870 2880
LVSFTWMGLE AVHMYLALVK VFNIYIPNYI LKFCLVGWGI PAIMVAITVS VKKDLYGTLS
2890 2900 2910 2920 2930 2940
PTTPFCWIKD DSIFYISVVA YFCLIFLMNL SMFCTVLVQL NSVKSQIQKT RRKMILHDLK
2950 2960 2970 2980 2990 3000
GTMSLTFLLG LTWGFAFFAW GPMRNFFLYL FAIFNTLQGF FIFVFHCVMK ESVREQWQIH
3010 3020 3030 3040 3050 3060
LCCGWLRLDN SSDGSSRCQI KVGYKQEGLK KIFEHKLLTP SLKSTATSST FKSLGSAQGT
3070 3080
PSEISFPNDD FDKDPYCSSP
10 20 30 40 50 60
MKEHIIYQKL YGLILMSSFI FLSDTLSLKG KKLDFFGRGD TYVSLIDTIP ELSRFTACID
70 80 90 100 110 120
LVFMDDNSRY WMAFSYITNN ALLGREDIDL GLAGDHQQLI LYRLGKTFSI RHHLASFQWH
130 140 150 160 170 180
TICLIWDGVK GKLELFLNKE RILEVTDQPH NLTPHGTLFL GHFLKNESSE VKSMMRSFPG
190 200 210 220 230 240
SLYYFQLWDH ILENEEFMKC LDGNIVSWEE DVWLVNKIIP TVDRTLRCFV PENMTIQEKS
250 260 270 280 290 300
TTVSQQIDMT TPSQITGVKP QNTAHSSTLL SQSIPIFATD YTTISYSNTT SPPLETMTAQ
310 320 330 340 350 360
KILKTLVDET ATFAVDVLST SSAISLPTQS ISIDNTTNSM KKTKSPSSES TKTTKMVEAM
370 380 390 400 410 420
ATEIFQPPTP SNFLSTSRFT KNSVVSTTSA IKSQSAVTKT TSLFSTIEST SMSTTPCLKQ
430 440 450 460 470 480
KSTNTGALPI STAGQEFIES TAAGTVPWFT VEKTSPASTH VGTASSFPPE PVLISTAAPV
490 500 510 520 530 540
DSVFPRNQTA FPLATTDMKI AFTVHSLTLP TRLIETTPAP RTAETELTST NFQDVSLPRV
550 560 570 580 590 600
EDAMSTSMSK ETSSKTFSFL TSFSFTGTES VQTVIDAEAT RTALTPEITL ASTVAETMLS
610 620 630 640 650 660
STITGRVYTQ NTPTADGHLL TLMSTRSAST SKAPESGPTS TTDEAAHLFS SNETIWTSRP
670 680 690 700 710 720
DQALLASMNT TTILTFVPNE NFTSAFHENT TYTEYLSATT NITPLKASPE GKGTTANDAT
730 740 750 760 770 780
TARYTTAVSK LTSPWFANFS IVSGTTSITN MPEFKLTTLL LKTIPMSTKP ANELPLTPRE
790 800 810 820 830 840
TVVPSVDIIS TLACIQPNFS TEESASETTQ TEINGAIVFG GTTTPVPKSA TTQRLNATVT
850 860 870 880 890 900
RKEATSHYLM RKSTIAAVAE VSPFSTMLEV TDESAQRVTA SVTVSSFPDI EKLSTPLDNK
910 920 930 940 950 960
TATTEVRESW LLTKLVKTTP RSSYNEMTEM FNFNHTYVAH WTSETSEGIS AGSPTSGSTH
970 980 990 1000 1010 1020
IFGEPLGAST TRISETSFST TPTDRTATSL SDGILPPQPT AAHSSATPVP VTHMFSLPVN
1030 1040 1050 1060 1070 1080
GSSVVAEETE VTMSEPSTLA RAFSTSVLSD VSNLSSTTMT TALVPPLDQT ASTTIVIVPT
1090 1100 1110 1120 1130 1140
HGDLIRTTSE ATVISVRKTS MAVPSLTETP FHSLRLSTPV TAKAETTLFS TSVDTVTPST
1150 1160 1170 1180 1190 1200
HTLVCSKPPP DNIPPASSTH VISTTSTPEA TQPISQVEET STYALSFPYT FSGGGVVASL
1210 1220 1230 1240 1250 1260
ATGTTETSVV DETTPSHISA NKLTTSVNSH ISSSATYRVH TPVSIQLVTS TSVLSSDKDQ
1270 1280 1290 1300 1310 1320
MTISLGKTPR TMEVTEMSPS KNSFISYSRG TPSLEMTDTG FPETTKISSH QTHSPSEIPL
1330 1340 1350 1360 1370 1380
GTPSDGNLAS SPTSGSTQIT PTLTSSNTVG VHIPEMSTSL GKTALPSQAL TITTFLCPEK
1390 1400 1410 1420 1430 1440
ESTSALPAYT PRTVEMIVNS TYVTHSVSYG QDTSFVDTTT SSSTRISNPM DINTTFSHLH
1450 1460 1470 1480 1490 1500
SLRTQPEVTS VASFISESTQ TFPESLSLST AGLYNDGFTV LSDRITTAFS VPNVPTMLPR
1510 1520 1530 1540 1550 1560
ESSMATSTPI YQMSSLPVNV TAFTSKKVSD TPPIVITKSS KTMHPGCLKS PCTATSGPMS
1570 1580 1590 1600 1610 1620
EMSSIPVNNS AFTPATVSSD TSTRVGLFST LLSSVTPRTT MTMQTSTLDV TPVIYAGATS
1630 1640 1650 1660 1670 1680
KNKMVSSAFT TEMIEAPSRI TPTTFLSPTE PTLPFVKTVP TTIMAGIVTP FVGTTAFSPL
1690 1700 1710 1720 1730 1740
SSKSTGAISS IPKTTFSPFL SATQQSSQAD EATTLGILSG ITNRSLSTVN SGTGVALTDT
1750 1760 1770 1780 1790 1800
YSRITVPENM LSPTHADSLH TSFNIQVSPS LTSFKSASGP TKNVKTTTNC FSSNTRKMTS
1810 1820 1830 1840 1850 1860
LLEKTSLTNY ATSLNTPVSY PPWTPSSATL PSLTSFVYSP HSTEAEISTP KTSPPPTSQM
1870 1880 1890 1900 1910 1920
VEFPVLGTRM TSSNTQPLLM TSWNIPTAEG SQFPISTTIN VPTSNEMETE TLHLVPGPLS
1930 1940 1950 1960 1970 1980
TFTASQTGLV SKDVMAMSSI PMSGILPNHG LSENPSLSTS LRAITSTLAD VKHTFEKMTT
1990 2000 2010 2020 2030 2040
SVTPGTTLPS ILSGATSGSV ISKSPILTWL LSSLPSGSPP ATVSNAPHVM TSSTVEVSKS
2050 2060 2070 2080 2090 2100
TFLTSDMISA HPFTNLTTLP SATMSTILTR TIPTPTLGGI TTGFPTSLPM SINVTDDIVY
2110 2120 2130 2140 2150 2160
ISTHPEASSR TTITANPRTV SHPSSFSRKT MSPSTTDHTL SVGAMPLPSS TITSSWNRIP
2170 2180 2190 2200 2210 2220
TASSPSTLII PKPTLDSLLN IMTTTSTVPG ASFPLISTGV TYPFTATVSS PISSFFETTW
2230 2240 2250 2260 2270 2280
LDSTPSFLST EASTSPTATK STVSFYNVEM SFSVFVEEPR IPITSVINEF TENSLNSIFQ
2290 2300 2310 2320 2330 2340
NSEFSLATLE TQIKSRDISE EEMVMDRAIL EQREGQEMAT ISYVPYSCVC QVIIKASSSL
2350 2360 2370 2380 2390 2400
ASSELMRKIK SKIHGNFTHG NFTQDQLTLL VNCEHVAVKK LEPGNCKADE TASKYKGTYK
2410 2420 2430 2440 2450 2460
WLLTNPTETA QTRCIKNEDG NATRFCSISI NTGKSQWEKP KFKQCKLLQE LPDKIVDLAN
2470 2480 2490 2500 2510 2520
ITISDENAED VAEHILNLIN ESPALGKEET KIIVSKISDI SQCDEISMNL THVMLQIINV
2530 2540 2550 2560 2570 2580
VLEKQNNSAS DLHEISNEIL RIIERTGHKM EFSGQIANLT VAGLALAVLR GDHTFDGMAF
2590 2600 2610 2620 2630 2640
SIHSYEEGTD PEIFLGNVPV GGILASIYLP KSLTERIPLS NLQTILFNFF GQTSLFKTKN
2650 2660 2670 2680 2690 2700
VTKALTTYVV SASISDDMFI QNLADPVVIT LQHIGGNQNY GQVHCAFWDF ENNNGLGGWN
2710 2720 2730 2740 2750 2760
SSGCKVKETN VNYTICQCDH LTHFGVLMDL SRSTVDSVNE QILALITYTG CGISSIFLGV
2770 2780 2790 2800 2810 2820
AVVTYIAFHK LRKDYPAKIL INLCTALLML NLVFLINSWL SSFQKVGVCI TAAVALHYFL
2830 2840 2850 2860 2870 2880
LVSFTWMGLE AVHMYLALVK VFNIYIPNYI LKFCLVGWGI PAIMVAITVS VKKDLYGTLS
2890 2900 2910 2920 2930 2940
PTTPFCWIKD DSIFYISVVA YFCLIFLMNL SMFCTVLVQL NSVKSQIQKT RRKMILHDLK
2950 2960 2970 2980 2990 3000
GTMSLTFLLG LTWGFAFFAW GPMRNFFLYL FAIFNTLQGF FIFVFHCVMK ESVREQWQIH
3010 3020 3030 3040 3050 3060
LCCGWLRLDN SSDGSSRCQI KVGYKQEGLK KIFEHKLLTP SLKSTATSST FKSLGSAQGT
3070 3080
PSEISFPNDD FDKDPYCSSP
Protein Neighborhood
Domains & Features
3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q8IZF6-1-unknown | MKEHII... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76236 | |||
| Q8IZF6-28-unknown | LKGKKL... | 28 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q8IZF6-64-unknown | MDDNSR... | 64 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76235 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...YCSSP | 3080 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...YCSSP | 3080 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt71854 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|