TopFIND 4.0

Q8K0H1: Multidrug and toxin extrusion protein 1

General Information

Protein names
- Multidrug and toxin extrusion protein 1
- MATE-1
- mMATE-1
- Solute carrier family 47 member 1
Gene names Slc47a1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8K0H1

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MERTEESAPG PGGADAASER RGLRCLLLPG FLEELRALLV LAGPAFLAQL MMFLISFISS 
        70         80         90        100        110        120 
VFCGHLGKLE LDAVTLAIAV INVTGISVGH GLSSACDTLI SQTYGSQNLK HVGVILQRGT 
       130        140        150        160        170        180 
LILLLCCFPC WALFINTEQI LLLFRQDPDV SRLTQTYVMI FIPALPAAFL YTLQVKYLLN 
       190        200        210        220        230        240 
QGIVLPQIMT GIAANLVNAL ANYVFLYHLH LGVMGSALAN TISQFALAIF LFLYILWRRL 
       250        260        270        280        290        300 
HQATWGGWSW ECLQDWASFL RLAIPSMLML CIEWWAYEVG SFLSGILGMV ELGAQSITYE 
       310        320        330        340        350        360 
LAIIVYMIPS GFSVAANVRV GNALGAGNID QAKKSSAISL IVTELFAVTF CVLLLGCKDL 
       370        380        390        400        410        420 
VGYIFTTDRD IVALVAQVIP IYAVSHLFEG LACTCGGILR GTGNQKVGAI VNAIGYYVIG 
       430        440        450        460        470        480 
LPIGIALMFA AKLGVIGLWS GIIICTTCQT TCFLAFIARL NWKRACQQAQ VHANLKVNVA 
       490        500        510        520        530        540 
LNSAVSHEPA HPVCPESHGE IMMTDLEKKD ETQLDQPMNQ QQALPIRPKD SNKLSGKQLA 
       550        560    
LRRGLLLLGV VLVLVGGILV RVYIRIE

Isoforms

- Isoform 2 of Multidrug and toxin extrusion protein 1

Sequence View

        10         20         30         40         50         60 
MERTEESAPG PGGADAASER RGLRCLLLPG FLEELRALLV LAGPAFLAQL MMFLISFISS 
        70         80         90        100        110        120 
VFCGHLGKLE LDAVTLAIAV INVTGISVGH GLSSACDTLI SQTYGSQNLK HVGVILQRGT 
       130        140        150        160        170        180 
LILLLCCFPC WALFINTEQI LLLFRQDPDV SRLTQTYVMI FIPALPAAFL YTLQVKYLLN 
       190        200        210        220        230        240 
QGIVLPQIMT GIAANLVNAL ANYVFLYHLH LGVMGSALAN TISQFALAIF LFLYILWRRL 
       250        260        270        280        290        300 
HQATWGGWSW ECLQDWASFL RLAIPSMLML CIEWWAYEVG SFLSGILGMV ELGAQSITYE 
       310        320        330        340        350        360 
LAIIVYMIPS GFSVAANVRV GNALGAGNID QAKKSSAISL IVTELFAVTF CVLLLGCKDL 
       370        380        390        400        410        420 
VGYIFTTDRD IVALVAQVIP IYAVSHLFEG LACTCGGILR GTGNQKVGAI VNAIGYYVIG 
       430        440        450        460        470        480 
LPIGIALMFA AKLGVIGLWS GIIICTTCQT TCFLAFIARL NWKRACQQAQ VHANLKVNVA 
       490        500        510        520        530        540 
LNSAVSHEPA HPVCPESHGE IMMTDLEKKD ETQLDQPMNQ QQALPIRPKD SNKLSGKQLA 
       550        560    
LRRGLLLLGV VLVLVGGILV RVYIRIE



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8K0H1-1-Acetylation MERTEE... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...YIRIE 567 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...YIRIE 567 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84369

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)