Q8K0Q5: Rho GTPase-activating protein 18

General Information

Protein names	- Rho GTPase-activating protein 18 - Rho-type GTPase-activating protein 18
Gene names	Arhgap18
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8K0Q5

3 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNWLSSSSGV VLTAYHPSGK DQVAGDSHVK GGDEATSSRR YGQYTINQEG STKVPERPPF
        70         80         90        100        110        120
DRSSSQDSLD ESMEAYWTEL ENIKRSNENR QEGQEAIVVK EPDEGELEEE WLKEAGLSNL
       130        140        150        160        170        180
FGESIDDPQE SILFLSTLTR TQAAAVQKRV ETVSQTLRKK NKQHHIRDVR DIFAQQREAQ
       190        200        210        220        230        240
EKPPDDSDLR SVRTNENKGQ GKDDQPSSGA VDSKEQISRV PEDTPASETD INLEVSFAEQ
       250        260        270        280        290        300
AVNQKEFSKE RTQKISSNDS LPSFRLPKDK TGTTRIGDLA PQDMKKVCSL SLIELTALYD
       310        320        330        340        350        360
VLGLEFKQQK AVKIKTRDSG LFGIPLTILL EQDQRKVPGT RIPLIFQKLI SRIEEGSLET
       370        380        390        400        410        420
EGLLRIPGAA MRIKNLCQEL EAKFYEGTFN WESVKQHDAA SLLKLFLREL PQPLLSMEYL
       430        440        450        460        470        480
KAFQAVQNLP TRKEQLQALN LLVILLPDAN RDTLKALLEF LQRVIDNKEK NKMTAGNVAM
       490        500        510        520        530        540
VMAPNLFMCH TLGLKSSEQR EFEMAAGTAN VMHLLIRYQK ILWTIPKFIV IQVRKQNIEN
       550        560        570        580        590        600
QKKERKAMKK LLKKMAYDRE KHEKQDKTAN GADVPQGVIR VQAPHLSKVS MAIQLTEELK
       610        620        630        640        650        660
ASDVLARFLS QESGVAQTLK KGEVFLYEIG GNIGERCLDD DTHMKDLYQL NPNAEWVIKS

KPV

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8K0Q5-1-unknown	MNWLSS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8K0Q5-73-unknown	MEAYWT...	73	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135030
Q8K0Q5-73-unknown	MEAYWT...	73	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135783
Q8K0Q5-238-unknown	AEQAVN...	238	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30812

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TQAAAV	145	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135783
...LEVSFA	237	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30812
...NDSLPS	262	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135030
...KSKPV	663	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	237	VSFA.\|.AEQA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> RHG18_MOUSE @237

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)