TopFIND 4.0

Q8K203: Endonuclease 8-like 3

General Information

Protein names
- Endonuclease 8-like 3
- 3.2.2.-
- 4.2.99.18
- DNA glycosylase FPG2
- DNA glycosylase/AP lyase Neil3
- Endonuclease VIII-like 3
- Nei-like protein 3
Gene names Neil3
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8K203

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVEGPGCTLN GEKIRARVLP GQAVTGVRGT ALQSLLGPAM SPAASLADVA TSAAPMNAKD 
        70         80         90        100        110        120 
SGWKLLRLFN GYVYSGVETL GKELFMYFGP RALRIHFGMK GSILINPREG ENRAGASPAL 
       130        140        150        160        170        180 
AVQLTRDLIC FYDSSVELRN SVESQQRVRV MEELDICSPK FSFSRAESEV KKQGDRMLCD 
       190        200        210        220        230        240 
VLLDQRVLPG VGNIIKNEAL FDSGLHPAVK VCQLSDKQAC HLVKMTRDFS ILFYRCCKAG 
       250        260        270        280        290        300 
SAISKHCKVY KRPNCDQCHS KITVCRFGEN SRMTYFCPHC QKENPQCVQV CQLPTRNTEI 
       310        320        330        340        350        360 
SWTPRGEDCF TDSVARKSEE QWSCVVCTLI NRPSAKACDA CLTTRPLDSV LKNRENSIAF 
       370        380        390        400        410        420 
NNLVKYPCNN FENTHTEVKI NRKTAFGNTT LVLTDLSNKS SALARKKRAN HTIDGESQMF 
       430        440        450        460        470        480 
LPTDIGFSDS QHPSKEGINY ITQPSNKVNI SPTVCAQSKL FSSAHKKFKP AHTSATELKS 
       490        500        510        520        530        540 
YNSGLSNSEL QTNRTRGHHS KSDGSPLCKM HHRRCVLRVV RKDGENKGRQ FYACSLPRGA 
       550        560        570        580        590        600 
QCGFFEWADL SFPFCRHGKR SIMKTVLKIG PNNGKNFFVC PLEKKKQCNF FQWAENGPGM 
   
EIVPGC

Isoforms

- Isoform 2 of Endonuclease 8-like 3

Sequence View

        10         20         30         40         50         60 
MVEGPGCTLN GEKIRARVLP GQAVTGVRGT ALQSLLGPAM SPAASLADVA TSAAPMNAKD 
        70         80         90        100        110        120 
SGWKLLRLFN GYVYSGVETL GKELFMYFGP RALRIHFGMK GSILINPREG ENRAGASPAL 
       130        140        150        160        170        180 
AVQLTRDLIC FYDSSVELRN SVESQQRVRV MEELDICSPK FSFSRAESEV KKQGDRMLCD 
       190        200        210        220        230        240 
VLLDQRVLPG VGNIIKNEAL FDSGLHPAVK VCQLSDKQAC HLVKMTRDFS ILFYRCCKAG 
       250        260        270        280        290        300 
SAISKHCKVY KRPNCDQCHS KITVCRFGEN SRMTYFCPHC QKENPQCVQV CQLPTRNTEI 
       310        320        330        340        350        360 
SWTPRGEDCF TDSVARKSEE QWSCVVCTLI NRPSAKACDA CLTTRPLDSV LKNRENSIAF 
       370        380        390        400        410        420 
NNLVKYPCNN FENTHTEVKI NRKTAFGNTT LVLTDLSNKS SALARKKRAN HTIDGESQMF 
       430        440        450        460        470        480 
LPTDIGFSDS QHPSKEGINY ITQPSNKVNI SPTVCAQSKL FSSAHKKFKP AHTSATELKS 
       490        500        510        520        530        540 
YNSGLSNSEL QTNRTRGHHS KSDGSPLCKM HHRRCVLRVV RKDGENKGRQ FYACSLPRGA 
       550        560        570        580        590        600 
QCGFFEWADL SFPFCRHGKR SIMKTVLKIG PNNGKNFFVC PLEKKKQCNF FQWAENGPGM 
   
EIVPGC



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Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8K203-1-unknown MVEGPG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82571
    Q8K203-2-unknown VEGPGC... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8K203-2-unknown VEGPGC... 2 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111229

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PAVKVC 211 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78189
    ...IVPGC 606 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)