TopFIND 4.0

Q8K595: Mucolipin-2

General Information

Protein names
- Mucolipin-2
- Transient receptor potential channel mucolipin 2
- TRPML2
Gene names Mcoln2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8K595

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPGDEETLDL PAWNRVPDLT WGPHHRSAMA SLDSEVREEC LREDLKFYFM SPCEKYRARR 
        70         80         90        100        110        120 
QIPWKLGLQI LKIVMVTTQL VRFGLSNQLV VAFKEDNTVA FKHLFLKGFS GVDEDDYSCS 
       130        140        150        160        170        180 
IYTQENTYES IFFAIKQYRH LKNISLATLG YGESEDNRTG LKVCKQHYKT GAMFSSNETL 
       190        200        210        220        230        240 
NIDSDIETDC IHLDLQVLTT EPEDWAQTSF FRLDFYRLVQ VDISFALKGI DLQAVHSREI 
       250        260        270        280        290        300 
PDCYLFQNTI TFDNTAHSGK IKIYLNSEAN IEECKNMNIS GSTQRSTHYL LVFDVFVIMI 
       310        320        330        340        350        360 
CLASLILCTR SIVLALRLRK RFLNFFLEKY KQRVCGADQW EFVNGWYVLV TISDLMTIIG 
       370        380        390        400        410        420 
SILKMEIKAK KLTNYDVCSI LLGTSTLFVW VGVIRYLGYF QTYNVLILTM QASLPKVLRF 
       430        440        450        460        470        480 
CACAGMIYLG YTFCGWIVLG PYHEKFENLN IVAECLFSLV NGDDMFATFA QIQQKSILVW 
       490        500        510        520        530        540 
LFSRLYLYSF ISLFIYMVLS LFIALITDSY HTIKKYQQHG FPETDLQKFL KESGSKDGYQ 
       550        560    
KQPSALLSCL CCLRRRRSND HLILID

Isoforms

- Isoform 2 of Mucolipin-2

Sequence View

        10         20         30         40         50         60 
MPGDEETLDL PAWNRVPDLT WGPHHRSAMA SLDSEVREEC LREDLKFYFM SPCEKYRARR 
        70         80         90        100        110        120 
QIPWKLGLQI LKIVMVTTQL VRFGLSNQLV VAFKEDNTVA FKHLFLKGFS GVDEDDYSCS 
       130        140        150        160        170        180 
IYTQENTYES IFFAIKQYRH LKNISLATLG YGESEDNRTG LKVCKQHYKT GAMFSSNETL 
       190        200        210        220        230        240 
NIDSDIETDC IHLDLQVLTT EPEDWAQTSF FRLDFYRLVQ VDISFALKGI DLQAVHSREI 
       250        260        270        280        290        300 
PDCYLFQNTI TFDNTAHSGK IKIYLNSEAN IEECKNMNIS GSTQRSTHYL LVFDVFVIMI 
       310        320        330        340        350        360 
CLASLILCTR SIVLALRLRK RFLNFFLEKY KQRVCGADQW EFVNGWYVLV TISDLMTIIG 
       370        380        390        400        410        420 
SILKMEIKAK KLTNYDVCSI LLGTSTLFVW VGVIRYLGYF QTYNVLILTM QASLPKVLRF 
       430        440        450        460        470        480 
CACAGMIYLG YTFCGWIVLG PYHEKFENLN IVAECLFSLV NGDDMFATFA QIQQKSILVW 
       490        500        510        520        530        540 
LFSRLYLYSF ISLFIYMVLS LFIALITDSY HTIKKYQQHG FPETDLQKFL KESGSKDGYQ 
       550        560    
KQPSALLSCL CCLRRRRSND HLILID



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8K595-1-unknown MPGDEE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8K595-29-unknown MASLDS... 29 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80625

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LILID 566 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LILID 566 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76243

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)