TopFIND 4.0

Q8LGU1: ABC transporter C family member 8

General Information

Protein names
- ABC transporter C family member 8
- ABC transporter ABCC.8
- AtABCC8
- 7.6.2.2
- ATP-energized glutathione S-conjugate pump 6
- Glutathione S-conjugate-transporting ATPase 6
- Multidrug resistance-associated protein 6
Gene names ABCC8
Organism Arabidopsis thaliana
Protease Family
Protease ID
Chromosome location
UniProt ID Q8LGU1

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAFIGSLPW CDVELNLASS CFQRTAIAFV NLLFLCIFYL FLIASCVSTH FIVRGRKKGW 
        70         80         90        100        110        120 
IFVAVAICCA ITSFIFLGVG LNSLIHGGND VTEISWVACF VEGIIWVSLA VSLLVNGSKW 
       130        140        150        160        170        180 
VNILVSVWWV SFALLDLVAK SGILLQGNGI RILDILTLPM SLLLLLCSWM NLRSSSAAAQ 
       190        200        210        220        230        240 
DCSVTGLSDP LLTKNPRKES ARLATAGFFS ILSFSWMNPL LSLGFKKPLS PEDIPSVVPE 
       250        260        270        280        290        300 
DEAQLAYKKF SQAWDTLLGD ESSTKERNLV FRAVVKVYFK ENIFIAVFAF LRTFAVVSLP 
       310        320        330        340        350        360 
LMLYVFVDYA NSDHRDLRNG FFNLACLVML KLVESLTMRH WYFASRRSGM RIRSALMVAA 
       370        380        390        400        410        420 
YKKQLKLSSL GRKRHSSGEI VNYIAVDAYR MGEFLWWFHS GWSLSLQLLL STAVLFGVVG 
       430        440        450        460        470        480 
AGAFPGLILL LLCGLLNLPF AKMLQNCQTQ FMIAQDKRLR STSEILNSMK VIKLQSWEDE 
       490        500        510        520        530        540 
FKKKIESCRD DEFTWLAKAQ LTKAFGSFLY WMSPTIVSSV VFLGCALLKS APLNASTIFT 
       550        560        570        580        590        600 
VLATLRVMSE PVKIIPDAIS AIIQGNVSFQ RLNNFLLDDE LKMDEIERSG LDASGTAVDI 
       610        620        630        640        650        660 
QVGNFGWEPE TKIPTLRNIH LEIKHGQKVA VCGPVGAGKS SLLHAVLGEI PKVSGTVKVF 
       670        680        690        700        710        720 
GSIAYVSQTS WIQSGTIRDN ILYGKPMESR RYNAAIKACA LDKDMNGFGH GDLTEIGQRG 
       730        740        750        760        770        780 
INLSGGQKQR IQLARAVYAD ADVYLLDDPF SAVDAHTAGV LFHKCVEDSL KEKTVILVTH 
       790        800        810        820        830        840 
QVEFLSEVDQ ILVMEEGTIT QSGKYEELLM MGTAFQQLVN AHNDAVTVLP LASNESLGDL 
       850        860        870        880        890        900 
RKEGKDREIR NMTVVEKIEE EIEKTDIPGV QLTQEEEKES GYVGMKPFLD YIGVSRGWCL 
       910        920        930        940        950        960 
LWSSVLGQVG FVVFQAASTY WLAFAIGIPK ITNTMLIGVY SIISTLSAGF VYARAITTAH 
       970        980        990       1000       1010       1020 
LGLKASKAFF SGFTNAVFKA PMLFFDSTPV GRILTRASSD LNVLDYDVPF AFIFVVAPAV 
      1030       1040       1050       1060       1070       1080 
ELTAALLIMT YVTWQVIIIA LLALAATKVV QDYYLASARE LIRINGTTKA PVMNYAAETS 
      1090       1100       1110       1120       1130       1140 
LGVVTIRAFG TAERFFKNYL NLVDADAVLF FLSNAAMEWV ILRIETLQNV TLFTCALLLI 
      1150       1160       1170       1180       1190       1200 
LIPKGYIAPG LVGLSLSYAL TLTQTQVFLT RWYCTLSNSI ISVERIKQYM NIPEEPPAII 
      1210       1220       1230       1240       1250       1260 
DDKRPPSSWP SNGTIHLQEL KIRYRPNAPL VLKGISCTFR EGTRVGVVGR TGSGKSTLIS 
      1270       1280       1290       1300       1310       1320 
ALFRLVEPAS GCILIDGIDI SKIGLKDLRM KLSIIPQEPT LFRGCIRTNL DPLGVYSDDE 
      1330       1340       1350       1360       1370       1380 
IWKALEKCQL KTTISNLPNK LDSSVSDEGE NWSVGQRQLF CLGRVLLKRN KILVLDEATA 
      1390       1400       1410       1420       1430       1440 
SIDSATDAII QRIIREEFAD CTVITVAHRV PTVIDSDMVM VLSFGDLVEY NEPSKLMETD 
      1450       1460    
SYFSKLVAEY WASCRGNSSQ NLQL

Isoforms

- Isoform 2 of ABC transporter C family member 8

Sequence View

        10         20         30         40         50         60 
MAAFIGSLPW CDVELNLASS CFQRTAIAFV NLLFLCIFYL FLIASCVSTH FIVRGRKKGW 
        70         80         90        100        110        120 
IFVAVAICCA ITSFIFLGVG LNSLIHGGND VTEISWVACF VEGIIWVSLA VSLLVNGSKW 
       130        140        150        160        170        180 
VNILVSVWWV SFALLDLVAK SGILLQGNGI RILDILTLPM SLLLLLCSWM NLRSSSAAAQ 
       190        200        210        220        230        240 
DCSVTGLSDP LLTKNPRKES ARLATAGFFS ILSFSWMNPL LSLGFKKPLS PEDIPSVVPE 
       250        260        270        280        290        300 
DEAQLAYKKF SQAWDTLLGD ESSTKERNLV FRAVVKVYFK ENIFIAVFAF LRTFAVVSLP 
       310        320        330        340        350        360 
LMLYVFVDYA NSDHRDLRNG FFNLACLVML KLVESLTMRH WYFASRRSGM RIRSALMVAA 
       370        380        390        400        410        420 
YKKQLKLSSL GRKRHSSGEI VNYIAVDAYR MGEFLWWFHS GWSLSLQLLL STAVLFGVVG 
       430        440        450        460        470        480 
AGAFPGLILL LLCGLLNLPF AKMLQNCQTQ FMIAQDKRLR STSEILNSMK VIKLQSWEDE 
       490        500        510        520        530        540 
FKKKIESCRD DEFTWLAKAQ LTKAFGSFLY WMSPTIVSSV VFLGCALLKS APLNASTIFT 
       550        560        570        580        590        600 
VLATLRVMSE PVKIIPDAIS AIIQGNVSFQ RLNNFLLDDE LKMDEIERSG LDASGTAVDI 
       610        620        630        640        650        660 
QVGNFGWEPE TKIPTLRNIH LEIKHGQKVA VCGPVGAGKS SLLHAVLGEI PKVSGTVKVF 
       670        680        690        700        710        720 
GSIAYVSQTS WIQSGTIRDN ILYGKPMESR RYNAAIKACA LDKDMNGFGH GDLTEIGQRG 
       730        740        750        760        770        780 
INLSGGQKQR IQLARAVYAD ADVYLLDDPF SAVDAHTAGV LFHKCVEDSL KEKTVILVTH 
       790        800        810        820        830        840 
QVEFLSEVDQ ILVMEEGTIT QSGKYEELLM MGTAFQQLVN AHNDAVTVLP LASNESLGDL 
       850        860        870        880        890        900 
RKEGKDREIR NMTVVEKIEE EIEKTDIPGV QLTQEEEKES GYVGMKPFLD YIGVSRGWCL 
       910        920        930        940        950        960 
LWSSVLGQVG FVVFQAASTY WLAFAIGIPK ITNTMLIGVY SIISTLSAGF VYARAITTAH 
       970        980        990       1000       1010       1020 
LGLKASKAFF SGFTNAVFKA PMLFFDSTPV GRILTRASSD LNVLDYDVPF AFIFVVAPAV 
      1030       1040       1050       1060       1070       1080 
ELTAALLIMT YVTWQVIIIA LLALAATKVV QDYYLASARE LIRINGTTKA PVMNYAAETS 
      1090       1100       1110       1120       1130       1140 
LGVVTIRAFG TAERFFKNYL NLVDADAVLF FLSNAAMEWV ILRIETLQNV TLFTCALLLI 
      1150       1160       1170       1180       1190       1200 
LIPKGYIAPG LVGLSLSYAL TLTQTQVFLT RWYCTLSNSI ISVERIKQYM NIPEEPPAII 
      1210       1220       1230       1240       1250       1260 
DDKRPPSSWP SNGTIHLQEL KIRYRPNAPL VLKGISCTFR EGTRVGVVGR TGSGKSTLIS 
      1270       1280       1290       1300       1310       1320 
ALFRLVEPAS GCILIDGIDI SKIGLKDLRM KLSIIPQEPT LFRGCIRTNL DPLGVYSDDE 
      1330       1340       1350       1360       1370       1380 
IWKALEKCQL KTTISNLPNK LDSSVSDEGE NWSVGQRQLF CLGRVLLKRN KILVLDEATA 
      1390       1400       1410       1420       1430       1440 
SIDSATDAII QRIIREEFAD CTVITVAHRV PTVIDSDMVM VLSFGDLVEY NEPSKLMETD 
      1450       1460    
SYFSKLVAEY WASCRGNSSQ NLQL



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8LGU1-1-unknown MAAFIG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65924
    Q8LGU1-23-unknown QRTAIA... 23 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8LGU1-23-unknown QRTAIA... 23 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113397

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QNLQL 1464 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...QNLQL 1464 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61542

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)