TopFIND 4.0

Q8N118: Cytochrome P450 4X1

General Information

Protein names
- Cytochrome P450 4X1
- 1.14.14.1
- CYPIVX1
Gene names CYP4X1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N118

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEFSWLETRW ARPFYLAFVF CLALGLLQAI KLYLRRQRLL RDLRPFPAPP THWFLGHQKF 
        70         80         90        100        110        120 
IQDDNMEKLE EIIEKYPRAF PFWIGPFQAF FCIYDPDYAK TLLSRTDPKS QYLQKFSPPL 
       130        140        150        160        170        180 
LGKGLAALDG PKWFQHRRLL TPGFHFNILK AYIEVMAHSV KMMLDKWEKI CSTQDTSVEV 
       190        200        210        220        230        240 
YEHINSMSLD IIMKCAFSKE TNCQTNSTHD PYAKAIFELS KIIFHRLYSL LYHSDIIFKL 
       250        260        270        280        290        300 
SPQGYRFQKL SRVLNQYTDT IIQERKKSLQ AGVKQDNTPK RKYQDFLDIV LSAKDESGSS 
       310        320        330        340        350        360 
FSDIDVHSEV STFLLAGHDT LAASISWILY CLALNPEHQE RCREEVRGIL GDGSSITWDQ 
       370        380        390        400        410        420 
LGEMSYTTMC IKETCRLIPA VPSISRDLSK PLTFPDGCTL PAGITVVLSI WGLHHNPAVW 
       430        440        450        460        470        480 
KNPKVFDPLR FSQENSDQRH PYAYLPFSAG SRNCIGQEFA MIELKVTIAL ILLHFRVTPD 
       490        500    
PTRPLTFPNH FILKPKNGMY LHLKKLSEC

Isoforms

- Isoform 2 of Cytochrome P450 4X1 - Isoform 3 of Cytochrome P450 4X1

Sequence View

        10         20         30         40         50         60 
MEFSWLETRW ARPFYLAFVF CLALGLLQAI KLYLRRQRLL RDLRPFPAPP THWFLGHQKF 
        70         80         90        100        110        120 
IQDDNMEKLE EIIEKYPRAF PFWIGPFQAF FCIYDPDYAK TLLSRTDPKS QYLQKFSPPL 
       130        140        150        160        170        180 
LGKGLAALDG PKWFQHRRLL TPGFHFNILK AYIEVMAHSV KMMLDKWEKI CSTQDTSVEV 
       190        200        210        220        230        240 
YEHINSMSLD IIMKCAFSKE TNCQTNSTHD PYAKAIFELS KIIFHRLYSL LYHSDIIFKL 
       250        260        270        280        290        300 
SPQGYRFQKL SRVLNQYTDT IIQERKKSLQ AGVKQDNTPK RKYQDFLDIV LSAKDESGSS 
       310        320        330        340        350        360 
FSDIDVHSEV STFLLAGHDT LAASISWILY CLALNPEHQE RCREEVRGIL GDGSSITWDQ 
       370        380        390        400        410        420 
LGEMSYTTMC IKETCRLIPA VPSISRDLSK PLTFPDGCTL PAGITVVLSI WGLHHNPAVW 
       430        440        450        460        470        480 
KNPKVFDPLR FSQENSDQRH PYAYLPFSAG SRNCIGQEFA MIELKVTIAL ILLHFRVTPD 
       490        500    
PTRPLTFPNH FILKPKNGMY LHLKKLSEC         10         20         30         40         50         60 
MEFSWLETRW ARPFYLAFVF CLALGLLQAI KLYLRRQRLL RDLRPFPAPP THWFLGHQKF 
        70         80         90        100        110        120 
IQDDNMEKLE EIIEKYPRAF PFWIGPFQAF FCIYDPDYAK TLLSRTDPKS QYLQKFSPPL 
       130        140        150        160        170        180 
LGKGLAALDG PKWFQHRRLL TPGFHFNILK AYIEVMAHSV KMMLDKWEKI CSTQDTSVEV 
       190        200        210        220        230        240 
YEHINSMSLD IIMKCAFSKE TNCQTNSTHD PYAKAIFELS KIIFHRLYSL LYHSDIIFKL 
       250        260        270        280        290        300 
SPQGYRFQKL SRVLNQYTDT IIQERKKSLQ AGVKQDNTPK RKYQDFLDIV LSAKDESGSS 
       310        320        330        340        350        360 
FSDIDVHSEV STFLLAGHDT LAASISWILY CLALNPEHQE RCREEVRGIL GDGSSITWDQ 
       370        380        390        400        410        420 
LGEMSYTTMC IKETCRLIPA VPSISRDLSK PLTFPDGCTL PAGITVVLSI WGLHHNPAVW 
       430        440        450        460        470        480 
KNPKVFDPLR FSQENSDQRH PYAYLPFSAG SRNCIGQEFA MIELKVTIAL ILLHFRVTPD 
       490        500    
PTRPLTFPNH FILKPKNGMY LHLKKLSEC



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Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N118-1-unknown MEFSWL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N118-66-unknown MEKLEE... 66 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71535
    Q8N118-66-unknown MEKLEE... 66 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt102183

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)