TopFIND 4.0

Q8N1N4: Keratin, type II cytoskeletal 78

General Information

Protein names
- Keratin, type II cytoskeletal 78
- Cytokeratin-78
- CK-78
- Keratin-5b
- Keratin-78
- K78
- Type-II keratin Kb40
Gene names KRT78
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N1N4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSLSPCRAQR GFSARSACSA RSRGRSRGGF SSRGGFSSRS LNSFGGCLEG SRGSTWGSGG 
        70         80         90        100        110        120 
RLGVRFGEWS GGPGLSLCPP GGIQEVTINQ NLLTPLKIEI DPQFQVVRTQ ETQEIRTLNN 
       130        140        150        160        170        180 
QFASFIDKVR FLEQQNKVLE TKWHLLQQQG LSGSQQGLEP VFEACLDQLR KQLEQLQGER 
       190        200        210        220        230        240 
GALDAELKAC RDQEEEYKSK YEEEAHRRAT LENDFVVLKK DVDGVFLSKM ELEGKLEALR 
       250        260        270        280        290        300 
EYLYFLKHLN EEELGQLQTQ ASDTSVVLSM DNNRYLDFSS IITEVRARYE EIARSSKAEA 
       310        320        330        340        350        360 
EALYQTKYQE LQVSAQLHGD RMQETKVQIS QLHQEIQRLQ SQTENLKKQN ASLQAAITDA 
       370        380        390        400        410        420 
EQRGELALKD AQAKVDELEA ALRMAKQNLA RLLCEYQELT STKLSLDVEI ATYRRLLEGE 
       430        440        450        460        470        480 
ECRMSGECTS QVTISSVGGS AVMSGGVGGG LGSTCGLGSG KGSPGSCCTS IVTGGSNIIL 
       490        500        510        520    
GSGKDPVLDS CSVSGSSAGS SCHTILKKTV ESSLKTSITY 

Isoforms

- Isoform 2 of Keratin, type II cytoskeletal 78

Sequence View

        10         20         30         40         50         60 
MSLSPCRAQR GFSARSACSA RSRGRSRGGF SSRGGFSSRS LNSFGGCLEG SRGSTWGSGG 
        70         80         90        100        110        120 
RLGVRFGEWS GGPGLSLCPP GGIQEVTINQ NLLTPLKIEI DPQFQVVRTQ ETQEIRTLNN 
       130        140        150        160        170        180 
QFASFIDKVR FLEQQNKVLE TKWHLLQQQG LSGSQQGLEP VFEACLDQLR KQLEQLQGER 
       190        200        210        220        230        240 
GALDAELKAC RDQEEEYKSK YEEEAHRRAT LENDFVVLKK DVDGVFLSKM ELEGKLEALR 
       250        260        270        280        290        300 
EYLYFLKHLN EEELGQLQTQ ASDTSVVLSM DNNRYLDFSS IITEVRARYE EIARSSKAEA 
       310        320        330        340        350        360 
EALYQTKYQE LQVSAQLHGD RMQETKVQIS QLHQEIQRLQ SQTENLKKQN ASLQAAITDA 
       370        380        390        400        410        420 
EQRGELALKD AQAKVDELEA ALRMAKQNLA RLLCEYQELT STKLSLDVEI ATYRRLLEGE 
       430        440        450        460        470        480 
ECRMSGECTS QVTISSVGGS AVMSGGVGGG LGSTCGLGSG KGSPGSCCTS IVTGGSNIIL 
       490        500        510        520    
GSGKDPVLDS CSVSGSSAGS SCHTILKKTV ESSLKTSITY 



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N1N4-1-unknown MSLSPC... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TSITY 520 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...TSITY 520 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74098

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)