TopFIND 4.0

Q8N2I9: Serine/threonine-protein kinase 40

General Information

Protein names
- Serine/threonine-protein kinase 40
- 2.7.11.1
- SINK-homologous serine/threonine-protein kinase
- Sugen kinase 495
- SgK495
Gene names STK40
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N2I9

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKRRASDRGA GETSARAKAL GSGISGNNAK RAGPFILGPR LGNSPVPSIV QCLARKDGTD 
        70         80         90        100        110        120 
DFYQLKILTL EERGDQGIES QEERQGKMLL HTEYSLLSLL HTQDGVVHHH GLFQDRTCEI 
       130        140        150        160        170        180 
VEDTESSRMV KKMKKRICLV LDCLCAHDFS DKTADLINLQ HYVIKEKRLS ERETVVIFYD 
       190        200        210        220        230        240 
VVRVVEALHQ KNIVHRDLKL GNMVLNKRTH RITITNFCLG KHLVSEGDLL KDQRGSPAYI 
       250        260        270        280        290        300 
SPDVLSGRPY RGKPSDMWAL GVVLFTMLYG QFPFYDSIPQ ELFRKIKAAE YTIPEDGRVS 
       310        320        330        340        350        360 
ENTVCLIRKL LVLDPQQRLA AADVLEALSA IIASWQSLSS LSGPLQVVPD IDDQMSNADS 
       370        380        390        400        410        420 
SQEAKVTEEC SQYEFENYMR QQLLLAEEKS SIHDARSWVP KRQFGSAPPV RRLGHDAQPM 
       430    
TSLDTAILAQ RYLRK

Isoforms

- Isoform 2 of Serine/threonine-protein kinase 40 - Isoform 3 of Serine/threonine-protein kinase 40 - Isoform 4 of Serine/threonine-protein kinase 40

Sequence View

        10         20         30         40         50         60 
MKRRASDRGA GETSARAKAL GSGISGNNAK RAGPFILGPR LGNSPVPSIV QCLARKDGTD 
        70         80         90        100        110        120 
DFYQLKILTL EERGDQGIES QEERQGKMLL HTEYSLLSLL HTQDGVVHHH GLFQDRTCEI 
       130        140        150        160        170        180 
VEDTESSRMV KKMKKRICLV LDCLCAHDFS DKTADLINLQ HYVIKEKRLS ERETVVIFYD 
       190        200        210        220        230        240 
VVRVVEALHQ KNIVHRDLKL GNMVLNKRTH RITITNFCLG KHLVSEGDLL KDQRGSPAYI 
       250        260        270        280        290        300 
SPDVLSGRPY RGKPSDMWAL GVVLFTMLYG QFPFYDSIPQ ELFRKIKAAE YTIPEDGRVS 
       310        320        330        340        350        360 
ENTVCLIRKL LVLDPQQRLA AADVLEALSA IIASWQSLSS LSGPLQVVPD IDDQMSNADS 
       370        380        390        400        410        420 
SQEAKVTEEC SQYEFENYMR QQLLLAEEKS SIHDARSWVP KRQFGSAPPV RRLGHDAQPM 
       430    
TSLDTAILAQ RYLRK         10         20         30         40         50         60 
MKRRASDRGA GETSARAKAL GSGISGNNAK RAGPFILGPR LGNSPVPSIV QCLARKDGTD 
        70         80         90        100        110        120 
DFYQLKILTL EERGDQGIES QEERQGKMLL HTEYSLLSLL HTQDGVVHHH GLFQDRTCEI 
       130        140        150        160        170        180 
VEDTESSRMV KKMKKRICLV LDCLCAHDFS DKTADLINLQ HYVIKEKRLS ERETVVIFYD 
       190        200        210        220        230        240 
VVRVVEALHQ KNIVHRDLKL GNMVLNKRTH RITITNFCLG KHLVSEGDLL KDQRGSPAYI 
       250        260        270        280        290        300 
SPDVLSGRPY RGKPSDMWAL GVVLFTMLYG QFPFYDSIPQ ELFRKIKAAE YTIPEDGRVS 
       310        320        330        340        350        360 
ENTVCLIRKL LVLDPQQRLA AADVLEALSA IIASWQSLSS LSGPLQVVPD IDDQMSNADS 
       370        380        390        400        410        420 
SQEAKVTEEC SQYEFENYMR QQLLLAEEKS SIHDARSWVP KRQFGSAPPV RRLGHDAQPM 
       430    
TSLDTAILAQ RYLRK         10         20         30         40         50         60 
MKRRASDRGA GETSARAKAL GSGISGNNAK RAGPFILGPR LGNSPVPSIV QCLARKDGTD 
        70         80         90        100        110        120 
DFYQLKILTL EERGDQGIES QEERQGKMLL HTEYSLLSLL HTQDGVVHHH GLFQDRTCEI 
       130        140        150        160        170        180 
VEDTESSRMV KKMKKRICLV LDCLCAHDFS DKTADLINLQ HYVIKEKRLS ERETVVIFYD 
       190        200        210        220        230        240 
VVRVVEALHQ KNIVHRDLKL GNMVLNKRTH RITITNFCLG KHLVSEGDLL KDQRGSPAYI 
       250        260        270        280        290        300 
SPDVLSGRPY RGKPSDMWAL GVVLFTMLYG QFPFYDSIPQ ELFRKIKAAE YTIPEDGRVS 
       310        320        330        340        350        360 
ENTVCLIRKL LVLDPQQRLA AADVLEALSA IIASWQSLSS LSGPLQVVPD IDDQMSNADS 
       370        380        390        400        410        420 
SQEAKVTEEC SQYEFENYMR QQLLLAEEKS SIHDARSWVP KRQFGSAPPV RRLGHDAQPM 
       430    
TSLDTAILAQ RYLRK



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N2I9-1-unknown MKRRAS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N2I9-1-unknown MKRRAS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90931
    Q8N2I9-1-unknown MKRRAS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90932

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)