TopFIND 4.0

Q8N2W9: E3 SUMO-protein ligase PIAS4

General Information

Protein names
- E3 SUMO-protein ligase PIAS4
- 2.3.2.27 {ECO:0000269|PubMed:12511558, ECO:0000269|PubMed:12631292, ECO:0000269|PubMed:12727872, ECO:0000269|PubMed:15831457, ECO:0000269|PubMed:15976810, ECO:0000269|PubMed:22508508}
- PIASy
- Protein inhibitor of activated STAT protein 4
- Protein inhibitor of activated STAT protein gamma
- PIAS-gamma
- RING-type E3 ubiquitin transferase PIAS4 {ECO:0000305}
Gene names PIAS4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N2W9

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 
        70         80         90        100        110        120 
LYETRYAKKN SEPAPQPHRP LDPLTMHSTY DRAGAVPRTP LAGPNIDYPV LYGKYLNGLG 
       130        140        150        160        170        180 
RLPAKTLKPE VRLVKLPFFN MLDELLKPTE LVPQNNEKLQ ESPCIFALTP RQVELIRNSR 
       190        200        210        220        230        240 
ELQPGVKAVQ VVLRICYSDT SCPQEDQYPP NIAVKVNHSY CSVPGYYPSN KPGVEPKRPC 
       250        260        270        280        290        300 
RPINLTHLMY LSSATNRITV TWGNYGKSYS VALYLVRQLT SSELLQRLKT IGVKHPELCK 
       310        320        330        340        350        360 
ALVKEKLRLD PDSEIATTGV RVSLICPLVK MRLSVPCRAE TCAHLQCFDA VFYLQMNEKK 
       370        380        390        400        410        420 
PTWMCPVCDK PAPYDQLIID GLLSKILSEC EDADEIEYLV DGSWCPIRAE KERSCSPQGA 
       430        440        450        460        470        480 
ILVLGPSDAN GLLPAPSVNG SGALGSTGGG GPVGSMENGK PGADVVDLTL DSSSSSEDEE 
       490        500        510    
EEEEEEEDED EEGPRPKRRC PFQKGLVPAC 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LVPAC 510 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)