TopFIND 4.0

Q8N3R3: T-cell activation inhibitor, mitochondrial

General Information

Protein names
- T-cell activation inhibitor, mitochondrial
- Tolerance associated gene-1 protein
- TOAG-1
Gene names TCAIM
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N3R3

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFCHLRPMRR LCLEKIFPHW FPFSRALSGA EAVNALRPFY FAVHPDFFGQ HPVEREINEN 
        70         80         90        100        110        120 
SLKRLSVYLE NLQKPGFKSL KPTQLTFYVR ETDQSSSDGQ EPFSTSGFRA VKFTLHTRDL 
       130        140        150        160        170        180 
LSTVLYILNS CSLSVEHIQS LNTNMHTQPL KEAKRMPDRP IKWDKSYYSF TGFKDPDEDL 
       190        200        210        220        230        240 
EQVSRVETTL TSWLDNNGKS AVKKLKNSLP LRKELDRLKD ELSHQLQLSD IRWQRSWGIA 
       250        260        270        280        290        300 
HRCSQLHSLS RLAQQNLETL KKAKGCTIIF TDRSGMSAVG HVMLGTMDVH HHWTKLFERL 
       310        320        330        340        350        360 
PSYFDLQRRL MILEDQISYL LGGIQVVYIE ELQPVLTLEE YYSLLDVFYN RLLKSRILFH 
       370        380        390        400        410        420 
PRSLRGLQMI LNSDRYAPSL HELGHFNIPT LCDPANLQWF ILTKAQQARE NMKRKEELKV 
       430        440        450        460        470        480 
IENELIQAST KKFSLEKLYK EPSISSIQMV DCCKRLLEQS LPYLHGMHLC ISHFYSVMQD 
       490    
GDLCIPWNWK NGEAIK

Isoforms

- Isoform 2 of T-cell activation inhibitor, mitochondrial - Isoform 3 of T-cell activation inhibitor, mitochondrial - Isoform 4 of T-cell activation inhibitor, mitochondrial

Sequence View

        10         20         30         40         50         60 
MFCHLRPMRR LCLEKIFPHW FPFSRALSGA EAVNALRPFY FAVHPDFFGQ HPVEREINEN 
        70         80         90        100        110        120 
SLKRLSVYLE NLQKPGFKSL KPTQLTFYVR ETDQSSSDGQ EPFSTSGFRA VKFTLHTRDL 
       130        140        150        160        170        180 
LSTVLYILNS CSLSVEHIQS LNTNMHTQPL KEAKRMPDRP IKWDKSYYSF TGFKDPDEDL 
       190        200        210        220        230        240 
EQVSRVETTL TSWLDNNGKS AVKKLKNSLP LRKELDRLKD ELSHQLQLSD IRWQRSWGIA 
       250        260        270        280        290        300 
HRCSQLHSLS RLAQQNLETL KKAKGCTIIF TDRSGMSAVG HVMLGTMDVH HHWTKLFERL 
       310        320        330        340        350        360 
PSYFDLQRRL MILEDQISYL LGGIQVVYIE ELQPVLTLEE YYSLLDVFYN RLLKSRILFH 
       370        380        390        400        410        420 
PRSLRGLQMI LNSDRYAPSL HELGHFNIPT LCDPANLQWF ILTKAQQARE NMKRKEELKV 
       430        440        450        460        470        480 
IENELIQAST KKFSLEKLYK EPSISSIQMV DCCKRLLEQS LPYLHGMHLC ISHFYSVMQD 
       490    
GDLCIPWNWK NGEAIK         10         20         30         40         50         60 
MFCHLRPMRR LCLEKIFPHW FPFSRALSGA EAVNALRPFY FAVHPDFFGQ HPVEREINEN 
        70         80         90        100        110        120 
SLKRLSVYLE NLQKPGFKSL KPTQLTFYVR ETDQSSSDGQ EPFSTSGFRA VKFTLHTRDL 
       130        140        150        160        170        180 
LSTVLYILNS CSLSVEHIQS LNTNMHTQPL KEAKRMPDRP IKWDKSYYSF TGFKDPDEDL 
       190        200        210        220        230        240 
EQVSRVETTL TSWLDNNGKS AVKKLKNSLP LRKELDRLKD ELSHQLQLSD IRWQRSWGIA 
       250        260        270        280        290        300 
HRCSQLHSLS RLAQQNLETL KKAKGCTIIF TDRSGMSAVG HVMLGTMDVH HHWTKLFERL 
       310        320        330        340        350        360 
PSYFDLQRRL MILEDQISYL LGGIQVVYIE ELQPVLTLEE YYSLLDVFYN RLLKSRILFH 
       370        380        390        400        410        420 
PRSLRGLQMI LNSDRYAPSL HELGHFNIPT LCDPANLQWF ILTKAQQARE NMKRKEELKV 
       430        440        450        460        470        480 
IENELIQAST KKFSLEKLYK EPSISSIQMV DCCKRLLEQS LPYLHGMHLC ISHFYSVMQD 
       490    
GDLCIPWNWK NGEAIK         10         20         30         40         50         60 
MFCHLRPMRR LCLEKIFPHW FPFSRALSGA EAVNALRPFY FAVHPDFFGQ HPVEREINEN 
        70         80         90        100        110        120 
SLKRLSVYLE NLQKPGFKSL KPTQLTFYVR ETDQSSSDGQ EPFSTSGFRA VKFTLHTRDL 
       130        140        150        160        170        180 
LSTVLYILNS CSLSVEHIQS LNTNMHTQPL KEAKRMPDRP IKWDKSYYSF TGFKDPDEDL 
       190        200        210        220        230        240 
EQVSRVETTL TSWLDNNGKS AVKKLKNSLP LRKELDRLKD ELSHQLQLSD IRWQRSWGIA 
       250        260        270        280        290        300 
HRCSQLHSLS RLAQQNLETL KKAKGCTIIF TDRSGMSAVG HVMLGTMDVH HHWTKLFERL 
       310        320        330        340        350        360 
PSYFDLQRRL MILEDQISYL LGGIQVVYIE ELQPVLTLEE YYSLLDVFYN RLLKSRILFH 
       370        380        390        400        410        420 
PRSLRGLQMI LNSDRYAPSL HELGHFNIPT LCDPANLQWF ILTKAQQARE NMKRKEELKV 
       430        440        450        460        470        480 
IENELIQAST KKFSLEKLYK EPSISSIQMV DCCKRLLEQS LPYLHGMHLC ISHFYSVMQD 
       490    
GDLCIPWNWK NGEAIK



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N3R3-1-unknown MFCHLR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N3R3-1-unknown MFCHLR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91696
    Q8N3R3-1-unknown MFCHLR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91697
    Q8N3R3-145-unknown MHTQPL... 145 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91698

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GEAIK 496 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GEAIK 496 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87316

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)