TopFIND 4.0

Q8N431: Ras-GEF domain-containing family member 1C

General Information

Protein names
- Ras-GEF domain-containing family member 1C
Gene names RASGEF1C
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N431

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPQTLSASDM VTPGSLSPPP TEPTDGEQAG QPLLDGAPSS ASLETLIQHL VPTADYYPEK 
        70         80         90        100        110        120 
AYIFTFLLSS RLFIEPRELL ARVCHLCIEQ QQLDKPVLDK ARVRKFGPKL LQLLAEWTET 
       130        140        150        160        170        180 
FPRDFQEEST IGHLKDVVGR IAPCDEAYRK RMHQLLQALH QKLAALRQGP EGLVGADKPI 
       190        200        210        220        230        240 
SYRTKPPASI HRELLGVCSD PYTLAQQLTH VELERLRHIG PEEFVQAFVN KDPLASTKPC 
       250        260        270        280        290        300 
FSDKTSNLEA YVKWFNRLCY LVATEICMPA KKKQRAQVIE FFIDVARECF NIGNFNSLMA 
       310        320        330        340        350        360 
IISGMNMSPV SRLKKTWAKV RTAKFFILEH QMDPTGNFCN YRTALRGAAH RSLTAHSSRE 
       370        380        390        400        410        420 
KIVIPFFSLL IKDIYFLNEG CANRLPNGHV NFEKFLELAK QVGEFITWKQ VECPFEQDAS 
       430        440        450        460    
ITHYLYTAPI FSEDGLYLAS YESESPENQT EKERWKALRS SILGKT

Isoforms

- Isoform 2 of Ras-GEF domain-containing family member 1C

Sequence View

        10         20         30         40         50         60 
MPQTLSASDM VTPGSLSPPP TEPTDGEQAG QPLLDGAPSS ASLETLIQHL VPTADYYPEK 
        70         80         90        100        110        120 
AYIFTFLLSS RLFIEPRELL ARVCHLCIEQ QQLDKPVLDK ARVRKFGPKL LQLLAEWTET 
       130        140        150        160        170        180 
FPRDFQEEST IGHLKDVVGR IAPCDEAYRK RMHQLLQALH QKLAALRQGP EGLVGADKPI 
       190        200        210        220        230        240 
SYRTKPPASI HRELLGVCSD PYTLAQQLTH VELERLRHIG PEEFVQAFVN KDPLASTKPC 
       250        260        270        280        290        300 
FSDKTSNLEA YVKWFNRLCY LVATEICMPA KKKQRAQVIE FFIDVARECF NIGNFNSLMA 
       310        320        330        340        350        360 
IISGMNMSPV SRLKKTWAKV RTAKFFILEH QMDPTGNFCN YRTALRGAAH RSLTAHSSRE 
       370        380        390        400        410        420 
KIVIPFFSLL IKDIYFLNEG CANRLPNGHV NFEKFLELAK QVGEFITWKQ VECPFEQDAS 
       430        440        450        460    
ITHYLYTAPI FSEDGLYLAS YESESPENQT EKERWKALRS SILGKT



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N431-1-unknown MPQTLS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N431-152-unknown MHQLLQ... 152 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87418

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ILGKT 466 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ILGKT 466 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt83036

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)