TopFIND 4.0

Q8N456: Leucine-rich repeat-containing protein 18

General Information

Protein names
- Leucine-rich repeat-containing protein 18
Gene names LRRC18
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N456

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVKGEKGPKG KKITLKVARN CIKITFDGKK RLDLSKMGIT TFPKCILRLS DMDELDLSRN 
        70         80         90        100        110        120 
LIRKIPDSIS KFQNLRWLDL HSNYIDKLPE SIGQMTSLLY LNVSNNRLTS NGLPVELKQL 
       130        140        150        160        170        180 
KNIRAVNLGL NHLDSVPTTL GALKELHEVG LHDNLLNNIP VSISKLPKLK KLNIKRNPFP 
       190        200        210        220        230        240 
KPGESEIFID SIRRLENLYV VEEKDLCAAC LRKCQNARDN LNRIKNMATT TPRKTIFPNL 
       250        260    
ISPNSMAKDS WEDWRIRLTS S

Isoforms

- Isoform 2 of Leucine-rich repeat-containing protein 18

Sequence View

        10         20         30         40         50         60 
MVKGEKGPKG KKITLKVARN CIKITFDGKK RLDLSKMGIT TFPKCILRLS DMDELDLSRN 
        70         80         90        100        110        120 
LIRKIPDSIS KFQNLRWLDL HSNYIDKLPE SIGQMTSLLY LNVSNNRLTS NGLPVELKQL 
       130        140        150        160        170        180 
KNIRAVNLGL NHLDSVPTTL GALKELHEVG LHDNLLNNIP VSISKLPKLK KLNIKRNPFP 
       190        200        210        220        230        240 
KPGESEIFID SIRRLENLYV VEEKDLCAAC LRKCQNARDN LNRIKNMATT TPRKTIFPNL 
       250        260    
ISPNSMAKDS WEDWRIRLTS S



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Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N456-1-unknown MVKGEK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N456-1-unknown MVKGEK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79885

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...WEDWRI 255 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt75503
    ...RLTSS 261 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)