Q8N543: Prolyl 3-hydroxylase OGFOD1

General Information

Protein names	- Prolyl 3-hydroxylase OGFOD1 - 1.14.11.- - 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1 - Termination and polyadenylation 1 homolog - uS12 prolyl 3-hydroxylase {ECO:0000303\|PubMed:25728928}
Gene names	OGFOD1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8N543

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNGKRPAEPG PARVGKKGKK EVMAEFSDAV TEETLKKQVA EAWSRRTPFS HEVIVMDMDP
        70         80         90        100        110        120
FLHCVIPNFI QSQDFLEGLQ KELMNLDFHE KYNDLYKFQQ SDDLKKRREP HISTLRKILF
       130        140        150        160        170        180
EDFRSWLSDI SKIDLESTID MSCAKYEFTD ALLCHDDELE GRRIAFILYL VPPWDRSMGG
       190        200        210        220        230        240
TLDLYSIDEH FQPKQIVKSL IPSWNKLVFF EVSPVSFHQV SEVLSEEKSR LSISGWFHGP
       250        260        270        280        290        300
SLTRPPNYFE PPIPRSPHIP QDHEILYDWI NPTYLDMDYQ VQIQEEFEES SEILLKEFLK
       310        320        330        340        350        360
PEKFTKVCEA LEHGHVEWSS RGPPNKRFYE KAEESKLPEI LKECMKLFRS EALFLLLSNF
       370        380        390        400        410        420
TGLKLHFLAP SEEDEMNDKK EAETTDITEE GTSHSPPEPE NNQMAISNNS QQSNEQTDPE
       430        440        450        460        470        480
PEENETKKES SVPMCQGELR HWKTGHYTLI HDHSKAEFAL DLILYCGCEG WEPEYGGFTS
       490        500        510        520        530        540
YIAKGEDEEL LTVNPESNSL ALVYRDRETL KFVKHINHRS LEQKKTFPNR TGFWDFSFIY

YE

Isoforms

- Isoform 2 of Prolyl 3-hydroxylase OGFOD1

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8N543-1-unknown	MNGKRP...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8N543-56-unknown	MDMDPF...	56	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457553
Q8N543-141-unknown	MSCAKY...	141	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83721

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RRIAFI	166	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456111
...RRIAFI	166	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155202
...EEKSRL	230	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457553
...FIYYE	542	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FIYYE	542	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79339

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)