TopFIND 4.0

Q8N594: MPN domain-containing protein

General Information

Protein names
- MPN domain-containing protein
- 3.4.-.-
Gene names MPND
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N594

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAPEPLSPA GGAGEEAPEE DEDEAEAEDP ERPNAGAGGG RSGGGGSSVS GGGGGGGAGA 
        70         80         90        100        110        120 
GGCGGPGGAL TRRAVTLRVL LKDALLEPGA GVLSIYYLGK KFLGDLQPDG RIMWQETGQT 
       130        140        150        160        170        180 
FNSPSAWATH CKKLVNPAKK SGCGWASVKY KGQKLDKYKA TWLRLHQLHT PATAADESPA 
       190        200        210        220        230        240 
SEGEEEELLM EEEEEDVLAG VSAEDKSRRP LGKSPSEPAH PEATTPGKRV DSKIRVPVRY 
       250        260        270        280        290        300 
CMLGSRDLAR NPHTLVEVTS FAAINKFQPF NVAVSSNVLF LLDFHSHLTR SEVVGYLGGR 
       310        320        330        340        350        360 
WDVNSQMLTV LRAFPCRSRL GDAETAAAIE EEIYQSLFLR GLSLVGWYHS HPHSPALPSL 
       370        380        390        400        410        420 
QDIDAQMDYQ LRLQGSSNGF QPCLALLCSP YYSGNPGPES KISPFWVMPP PEMLLVEFYK 
       430        440        450        460        470    
GSPDLVRLQE PWSQEHTYLD KLKISLASRT PKDQSLCHVL EQVCGVLKQG S

Isoforms

- Isoform 2 of MPN domain-containing protein

Sequence View

        10         20         30         40         50         60 
MAAPEPLSPA GGAGEEAPEE DEDEAEAEDP ERPNAGAGGG RSGGGGSSVS GGGGGGGAGA 
        70         80         90        100        110        120 
GGCGGPGGAL TRRAVTLRVL LKDALLEPGA GVLSIYYLGK KFLGDLQPDG RIMWQETGQT 
       130        140        150        160        170        180 
FNSPSAWATH CKKLVNPAKK SGCGWASVKY KGQKLDKYKA TWLRLHQLHT PATAADESPA 
       190        200        210        220        230        240 
SEGEEEELLM EEEEEDVLAG VSAEDKSRRP LGKSPSEPAH PEATTPGKRV DSKIRVPVRY 
       250        260        270        280        290        300 
CMLGSRDLAR NPHTLVEVTS FAAINKFQPF NVAVSSNVLF LLDFHSHLTR SEVVGYLGGR 
       310        320        330        340        350        360 
WDVNSQMLTV LRAFPCRSRL GDAETAAAIE EEIYQSLFLR GLSLVGWYHS HPHSPALPSL 
       370        380        390        400        410        420 
QDIDAQMDYQ LRLQGSSNGF QPCLALLCSP YYSGNPGPES KISPFWVMPP PEMLLVEFYK 
       430        440        450        460        470    
GSPDLVRLQE PWSQEHTYLD KLKISLASRT PKDQSLCHVL EQVCGVLKQG S



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Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N594-2-unknown MAAPEP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N594-1-unknown MAAPEP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81465
    Q8N594-2-Acetylation AAPEPL... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N594-2-Acetylation AAPEPL... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111694

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LKQGS 471 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LKQGS 471 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt77083

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)