Q8N5Y2: Male-specific lethal 3 homolog

General Information

Protein names	- Male-specific lethal 3 homolog - Male-specific lethal-3 homolog 1 - Male-specific lethal-3 protein-like 1 - MSL3-like 1
Gene names	MSL3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8N5Y2

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Male-specific lethal 3 homolog - Isoform 3 of Male-specific lethal 3 homolog - Isoform 4 of Male-specific lethal 3 homolog - Isoform 5 of Male-specific lethal 3 homolog - Isoform 6 of Male-specific lethal 3 homolog

Sequence View

        10         20         30         40         50         60
MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP EYLIHFNGWN
        70         80         90        100        110        120
RSWDRWAAED HVLRDTDENR RLQRKLARKA VARLRSTGRK KKRCRLPGVD SVLKGLPTEE
       130        140        150        160        170        180
KDENDENSLS SSSDCSENKD EEISEESDIE EKTEVKEEPE LQTRREMEER TITIEIPEVL
       190        200        210        220        230        240
KKQLEDDCYY INRRKRLVKL PCQTNIITIL ESYVKHFAIN AAFSANERPR HHHVMPHANM
       250        260        270        280        290        300
NVHYIPAEKN VDLCKEMVDG LRITFDYTLP LVLLYPYEQA QYKKVTSSKF FLPIKESATS
       310        320        330        340        350        360
TNRSQEELSP SPPLLNPSTP QSTESQPTTG EPATPKRRKA EPEALQSLRR STRHSANCDR
       370        380        390        400        410        420
LSESSASPQP KRRQQDTSAS MPKLFLHLEK KTPVHSRSSS PIPLTPSKEG SAVFAGFEGR
       430        440        450        460        470        480
RTNEINEVLS WKLVPDNYPP GDQPPPPSYI YGAQHLLRLF VKLPEILGKM SFSEKNLKAL
       490        500        510        520
LKHFDLFLRF LAEYHDDFFP ESAYVAACEA HYSTKNPRAI Y         10         20         30         40         50         60
MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP EYLIHFNGWN
        70         80         90        100        110        120
RSWDRWAAED HVLRDTDENR RLQRKLARKA VARLRSTGRK KKRCRLPGVD SVLKGLPTEE
       130        140        150        160        170        180
KDENDENSLS SSSDCSENKD EEISEESDIE EKTEVKEEPE LQTRREMEER TITIEIPEVL
       190        200        210        220        230        240
KKQLEDDCYY INRRKRLVKL PCQTNIITIL ESYVKHFAIN AAFSANERPR HHHVMPHANM
       250        260        270        280        290        300
NVHYIPAEKN VDLCKEMVDG LRITFDYTLP LVLLYPYEQA QYKKVTSSKF FLPIKESATS
       310        320        330        340        350        360
TNRSQEELSP SPPLLNPSTP QSTESQPTTG EPATPKRRKA EPEALQSLRR STRHSANCDR
       370        380        390        400        410        420
LSESSASPQP KRRQQDTSAS MPKLFLHLEK KTPVHSRSSS PIPLTPSKEG SAVFAGFEGR
       430        440        450        460        470        480
RTNEINEVLS WKLVPDNYPP GDQPPPPSYI YGAQHLLRLF VKLPEILGKM SFSEKNLKAL
       490        500        510        520
LKHFDLFLRF LAEYHDDFFP ESAYVAACEA HYSTKNPRAI Y         10         20         30         40         50         60
MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP EYLIHFNGWN
        70         80         90        100        110        120
RSWDRWAAED HVLRDTDENR RLQRKLARKA VARLRSTGRK KKRCRLPGVD SVLKGLPTEE
       130        140        150        160        170        180
KDENDENSLS SSSDCSENKD EEISEESDIE EKTEVKEEPE LQTRREMEER TITIEIPEVL
       190        200        210        220        230        240
KKQLEDDCYY INRRKRLVKL PCQTNIITIL ESYVKHFAIN AAFSANERPR HHHVMPHANM
       250        260        270        280        290        300
NVHYIPAEKN VDLCKEMVDG LRITFDYTLP LVLLYPYEQA QYKKVTSSKF FLPIKESATS
       310        320        330        340        350        360
TNRSQEELSP SPPLLNPSTP QSTESQPTTG EPATPKRRKA EPEALQSLRR STRHSANCDR
       370        380        390        400        410        420
LSESSASPQP KRRQQDTSAS MPKLFLHLEK KTPVHSRSSS PIPLTPSKEG SAVFAGFEGR
       430        440        450        460        470        480
RTNEINEVLS WKLVPDNYPP GDQPPPPSYI YGAQHLLRLF VKLPEILGKM SFSEKNLKAL
       490        500        510        520
LKHFDLFLRF LAEYHDDFFP ESAYVAACEA HYSTKNPRAI Y         10         20         30         40         50         60
MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP EYLIHFNGWN
        70         80         90        100        110        120
RSWDRWAAED HVLRDTDENR RLQRKLARKA VARLRSTGRK KKRCRLPGVD SVLKGLPTEE
       130        140        150        160        170        180
KDENDENSLS SSSDCSENKD EEISEESDIE EKTEVKEEPE LQTRREMEER TITIEIPEVL
       190        200        210        220        230        240
KKQLEDDCYY INRRKRLVKL PCQTNIITIL ESYVKHFAIN AAFSANERPR HHHVMPHANM
       250        260        270        280        290        300
NVHYIPAEKN VDLCKEMVDG LRITFDYTLP LVLLYPYEQA QYKKVTSSKF FLPIKESATS
       310        320        330        340        350        360
TNRSQEELSP SPPLLNPSTP QSTESQPTTG EPATPKRRKA EPEALQSLRR STRHSANCDR
       370        380        390        400        410        420
LSESSASPQP KRRQQDTSAS MPKLFLHLEK KTPVHSRSSS PIPLTPSKEG SAVFAGFEGR
       430        440        450        460        470        480
RTNEINEVLS WKLVPDNYPP GDQPPPPSYI YGAQHLLRLF VKLPEILGKM SFSEKNLKAL
       490        500        510        520
LKHFDLFLRF LAEYHDDFFP ESAYVAACEA HYSTKNPRAI Y         10         20         30         40         50         60
MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP EYLIHFNGWN
        70         80         90        100        110        120
RSWDRWAAED HVLRDTDENR RLQRKLARKA VARLRSTGRK KKRCRLPGVD SVLKGLPTEE
       130        140        150        160        170        180
KDENDENSLS SSSDCSENKD EEISEESDIE EKTEVKEEPE LQTRREMEER TITIEIPEVL
       190        200        210        220        230        240
KKQLEDDCYY INRRKRLVKL PCQTNIITIL ESYVKHFAIN AAFSANERPR HHHVMPHANM
       250        260        270        280        290        300
NVHYIPAEKN VDLCKEMVDG LRITFDYTLP LVLLYPYEQA QYKKVTSSKF FLPIKESATS
       310        320        330        340        350        360
TNRSQEELSP SPPLLNPSTP QSTESQPTTG EPATPKRRKA EPEALQSLRR STRHSANCDR
       370        380        390        400        410        420
LSESSASPQP KRRQQDTSAS MPKLFLHLEK KTPVHSRSSS PIPLTPSKEG SAVFAGFEGR
       430        440        450        460        470        480
RTNEINEVLS WKLVPDNYPP GDQPPPPSYI YGAQHLLRLF VKLPEILGKM SFSEKNLKAL
       490        500        510        520
LKHFDLFLRF LAEYHDDFFP ESAYVAACEA HYSTKNPRAI Y

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8N5Y2-1-unknown	MSASEG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8N5Y2-1-unknown	MSASEG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81596
Q8N5Y2-167-unknown	MEERTI...	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81595
Q8N5Y2-167-unknown	MEERTI...	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106355
Q8N5Y2-167-unknown	MEERTI...	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106354
Q8N5Y2-167-unknown	MEERTI...	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106353

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PRAIY	521	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PRAIY	521	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77213
...PRAIY	521	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77211
...PRAIY	521	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77212

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

Q8N5Y2: Male-specific lethal 3 homolog

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates