TopFIND 4.0

Q8N5Z0: Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial

General Information

Protein names
- Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
- KAT/AadAT
- 2-aminoadipate aminotransferase
- 2-aminoadipate transaminase
- 2.6.1.39
- Alpha-aminoadipate aminotransferase
- AadAT
- Kynurenine aminotransferase II
- Kynurenine--oxoglutarate aminotransferase II
- Kynurenine--oxoglutarate transaminase 2
- 2.6.1.7
- Kynurenine--oxoglutarate transaminase II
Gene names AADAT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N5Z0

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNYARFITAA SAARNPSPIR TMTDILSRGP KSMISLAGGL PNPNMFPFKT AVITVENGKT 
        70         80         90        100        110        120 
IQFGEEMMKR ALQYSPSAGI PELLSWLKQL QIKLHNPPTI HYPPSQGQMD LCVTSGSQQG 
       130        140        150        160        170        180 
LCKVFEMIIN PGDNVLLDEP AYSGTLQSLH PLGCNIINVA SDESGIVPDS LRDILSRWKP 
       190        200        210        220        230        240 
EDAKNPQKNT PKFLYTVPNG NNPTGNSLTS ERKKEIYELA RKYDFLIIED DPYYFLQFNK 
       250        260        270        280        290        300 
FRVPTFLSMD VDGRVIRADS FSKIISSGLR IGFLTGPKPL IERVILHIQV STLHPSTFNQ 
       310        320        330        340        350        360 
LMISQLLHEW GEEGFMAHVD RVIDFYSNQK DAILAAADKW LTGLAEWHVP AAGMFLWIKV 
       370        380        390        400        410        420 
KGINDVKELI EEKAVKMGVL MLPGNAFYVD SSAPSPYLRA SFSSASPEQM DVAFQVLAQL 
   
IKESL

Isoforms

- Isoform 2 of Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial

Sequence View

        10         20         30         40         50         60 
MNYARFITAA SAARNPSPIR TMTDILSRGP KSMISLAGGL PNPNMFPFKT AVITVENGKT 
        70         80         90        100        110        120 
IQFGEEMMKR ALQYSPSAGI PELLSWLKQL QIKLHNPPTI HYPPSQGQMD LCVTSGSQQG 
       130        140        150        160        170        180 
LCKVFEMIIN PGDNVLLDEP AYSGTLQSLH PLGCNIINVA SDESGIVPDS LRDILSRWKP 
       190        200        210        220        230        240 
EDAKNPQKNT PKFLYTVPNG NNPTGNSLTS ERKKEIYELA RKYDFLIIED DPYYFLQFNK 
       250        260        270        280        290        300 
FRVPTFLSMD VDGRVIRADS FSKIISSGLR IGFLTGPKPL IERVILHIQV STLHPSTFNQ 
       310        320        330        340        350        360 
LMISQLLHEW GEEGFMAHVD RVIDFYSNQK DAILAAADKW LTGLAEWHVP AAGMFLWIKV 
       370        380        390        400        410        420 
KGINDVKELI EEKAVKMGVL MLPGNAFYVD SSAPSPYLRA SFSSASPEQM DVAFQVLAQL 
   
IKESL



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N5Z0-1-unknown MNYARF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65884
    Q8N5Z0-30-unknown PKSMIS... 30 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N5Z0-30-unknown PKSMIS... 30 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt114732

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IKESL 425 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...IKESL 425 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61502

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)