TopFIND 4.0

Q8N7N5: DDB1- and CUL4-associated factor 8

General Information

Protein names
- DDB1- and CUL4-associated factor 8
- WD repeat-containing protein 42A
Gene names Dcaf8
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N7N5

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSNKRPNTTD GRTDLANGSL SSSPEEMSGA EEGRETSSGI EVEASDLSLS LTGDDGGPNR 
        70         80         90        100        110        120 
TSTESRGTDT ESSGEEKDSD SMEDTGHYSI NDESRGHGHS DEEDEEQPRH RGQRKRASRD 
       130        140        150        160        170        180 
QDSSDDERAL EDWVSSETTA LPRPRWQALP ALRERELGSS ARFVYEACGA RVFVQRFRLQ 
       190        200        210        220        230        240 
HGLEGHTGCV NTLHFNQRGT WLASGSDDLK VVVWDWVRRQ PVLDFESGHK SNVFQAKFLP 
       250        260        270        280        290        300 
NSGDSTLAMC ARDGQVRVAE LSATQCCKNT KRVAQHKGAS HKLALEPDSP CTFLSAGEDA 
       310        320        330        340        350        360 
VVFTIDLRQD RPASKLVVTK EKEKKVGLYT IYVNPANTHQ FAVGGRDQYV RIYDQRKIDE 
       370        380        390        400        410        420 
NENNGVLKKF CPHHLVNSES KANITCLVYS HDGTELLASY NDEDIYLFNS SHSDGAQYIK 
       430        440        450        460        470        480 
RYKGHRNNAT VKGVNFYGPK SEFVVSGSDC GHIFLWEKSS CQIIQFMEGD KGGVVNCLEP 
       490        500        510        520        530        540 
HPHLPVLATS GLDHDVKIWA PTAEASTELT GLKEVIKKNK RERDEDSLHH TDLFDSHMLW 
       550        560        570        580        590    
FLMHHLRQRR HHRRWREPGV GATDADSDES PSSSDTSDEE EGPDRVQCMP S

Isoforms

- Isoform 2 of DDB1- and CUL4-associated factor 8

Sequence View

        10         20         30         40         50         60 
MSNKRPNTTD GRTDLANGSL SSSPEEMSGA EEGRETSSGI EVEASDLSLS LTGDDGGPNR 
        70         80         90        100        110        120 
TSTESRGTDT ESSGEEKDSD SMEDTGHYSI NDESRGHGHS DEEDEEQPRH RGQRKRASRD 
       130        140        150        160        170        180 
QDSSDDERAL EDWVSSETTA LPRPRWQALP ALRERELGSS ARFVYEACGA RVFVQRFRLQ 
       190        200        210        220        230        240 
HGLEGHTGCV NTLHFNQRGT WLASGSDDLK VVVWDWVRRQ PVLDFESGHK SNVFQAKFLP 
       250        260        270        280        290        300 
NSGDSTLAMC ARDGQVRVAE LSATQCCKNT KRVAQHKGAS HKLALEPDSP CTFLSAGEDA 
       310        320        330        340        350        360 
VVFTIDLRQD RPASKLVVTK EKEKKVGLYT IYVNPANTHQ FAVGGRDQYV RIYDQRKIDE 
       370        380        390        400        410        420 
NENNGVLKKF CPHHLVNSES KANITCLVYS HDGTELLASY NDEDIYLFNS SHSDGAQYIK 
       430        440        450        460        470        480 
RYKGHRNNAT VKGVNFYGPK SEFVVSGSDC GHIFLWEKSS CQIIQFMEGD KGGVVNCLEP 
       490        500        510        520        530        540 
HPHLPVLATS GLDHDVKIWA PTAEASTELT GLKEVIKKNK RERDEDSLHH TDLFDSHMLW 
       550        560        570        580        590    
FLMHHLRQRR HHRRWREPGV GATDADSDES PSSSDTSDEE EGPDRVQCMP S



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N7N5-1-unknown MSNKRP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N7N5-1-unknown MSNKRP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt72427

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QCMPS 591 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)