Q8N8W4: Patatin-like phospholipase domain-containing protein 1

General Information

Protein names	- Patatin-like phospholipase domain-containing protein 1 - 3.1.1.-
Gene names	PNPLA1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8N8W4

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Patatin-like phospholipase domain-containing protein 1 - Isoform 3 of Patatin-like phospholipase domain-containing protein 1

Sequence View

        10         20         30         40         50         60
MEEQVFKGDP DTPHSISFSG SGFLSFYQAG AVDALRDLAP RMLETAHRFA GTSAGAVIAA
        70         80         90        100        110        120
LAICGIEMDE YLRVLNVGVA EVKKSFLGPL SPSCKMVQMM RQFLYRVLPE DSYKVTTGKL
       130        140        150        160        170        180
HVSLTRLTDG ENVVVSEFTS KEELIEALYC SCFVPVYCGL IPPTYRGVRY IDGGFTGMQP
       190        200        210        220        230        240
CAFWTDAITI STFSGQQDIC PRDCPAIFHD FRMFNCSFQF SLENIARMTH ALFPPDLVIL
       250        260        270        280        290        300
HDYYYRGYED AVLYLRRLNA VYLNSSSKRV IFPRVEVYCQ IELALGNECP ERSQPSLRAR
       310        320        330        340        350        360
QASLEGATQP HKEWVPKGDG RGSHGPPVSQ PVQTLEFTCE SPVSAPVSPL EQPPAQPLAS
       370        380        390        400        410        420
STPLSLSGMP PVSFPAVHKP PSSTPGSSLP TPPPGLSPLS PQQQVQPSGS PARSLHSQAP
       430        440        450        460        470        480
TSPRPSLGPS TVGAPQTLPR SSLSAFPAQP PVEELGQEQP QAVALLVSSK PKSAVPLVHV
       490        500        510        520        530
KETVSKPYVT ESPAEDSNWV NKVFKKNKQK TSGTRKGFPR HSGSKKPSSK VQ         10         20         30         40         50         60
MEEQVFKGDP DTPHSISFSG SGFLSFYQAG AVDALRDLAP RMLETAHRFA GTSAGAVIAA
        70         80         90        100        110        120
LAICGIEMDE YLRVLNVGVA EVKKSFLGPL SPSCKMVQMM RQFLYRVLPE DSYKVTTGKL
       130        140        150        160        170        180
HVSLTRLTDG ENVVVSEFTS KEELIEALYC SCFVPVYCGL IPPTYRGVRY IDGGFTGMQP
       190        200        210        220        230        240
CAFWTDAITI STFSGQQDIC PRDCPAIFHD FRMFNCSFQF SLENIARMTH ALFPPDLVIL
       250        260        270        280        290        300
HDYYYRGYED AVLYLRRLNA VYLNSSSKRV IFPRVEVYCQ IELALGNECP ERSQPSLRAR
       310        320        330        340        350        360
QASLEGATQP HKEWVPKGDG RGSHGPPVSQ PVQTLEFTCE SPVSAPVSPL EQPPAQPLAS
       370        380        390        400        410        420
STPLSLSGMP PVSFPAVHKP PSSTPGSSLP TPPPGLSPLS PQQQVQPSGS PARSLHSQAP
       430        440        450        460        470        480
TSPRPSLGPS TVGAPQTLPR SSLSAFPAQP PVEELGQEQP QAVALLVSSK PKSAVPLVHV
       490        500        510        520        530
KETVSKPYVT ESPAEDSNWV NKVFKKNKQK TSGTRKGFPR HSGSKKPSSK VQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8N8W4-1-unknown	MEEQVF...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8N8W4-96-unknown	MVQMMR...	96	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85585
Q8N8W4-96-unknown	MVQMMR...	96	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85586
Q8N8W4-96-unknown	MVQMMR...	96	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000321116
Q8N8W4-96-unknown	MVQMMR...	96	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000373367

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SSKVQ	532	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SSKVQ	532	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81203
...SSKVQ	532	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81204

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)