TopFIND 4.0

Q8N9B8: Ras-GEF domain-containing family member 1A

General Information

Protein names
- Ras-GEF domain-containing family member 1A
Gene names RASGEF1A
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8N9B8

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPQTSVVFSS ILGPSCSGQV QPGMGERGGG AGGGSGDLIF QDGHLISGSL EALMEHLVPT 
        70         80         90        100        110        120 
VDYYPDRTYI FTFLLSSRVF MPPHDLLARV GQICVEQKQQ LEAGPEKAKL KSFSAKIVQL 
       130        140        150        160        170        180 
LKEWTEAFPY DFQDEKAMAE LKAITHRVTQ CDEENGTVKK AIAQMTQSLL LSLAARSQLQ 
       190        200        210        220        230        240 
ELREKLRPPA VDKGPILKTK PPAAQKDILG VCCDPLVLAQ QLTHIELDRV SSIYPEDLMQ 
       250        260        270        280        290        300 
IVSHMDSLDN HRCRGDLTKT YSLEAYDNWF NCLSMLVATE VCRVVKKKHR TRMLEFFIDV 
       310        320        330        340        350        360 
ARECFNIGNF NSMMAIISGM NLSPVARLKK TWSKVKTAKF DVLEHHMDPS SNFCNYRTAL 
       370        380        390        400        410        420 
QGATQRSQMA NSSREKIVIP VFNLFVKDIY FLHKIHTNHL PNGHINFKKF WEISRQIHEF 
       430        440        450        460        470        480 
MTWTQVECPF EKDKKIQSYL LTAPIYSEEA LFVASFESEG PENHMEKDSW KTLRTTLLNR 
   
A

Isoforms

- Isoform 2 of Ras-GEF domain-containing family member 1A

Sequence View

        10         20         30         40         50         60 
MPQTSVVFSS ILGPSCSGQV QPGMGERGGG AGGGSGDLIF QDGHLISGSL EALMEHLVPT 
        70         80         90        100        110        120 
VDYYPDRTYI FTFLLSSRVF MPPHDLLARV GQICVEQKQQ LEAGPEKAKL KSFSAKIVQL 
       130        140        150        160        170        180 
LKEWTEAFPY DFQDEKAMAE LKAITHRVTQ CDEENGTVKK AIAQMTQSLL LSLAARSQLQ 
       190        200        210        220        230        240 
ELREKLRPPA VDKGPILKTK PPAAQKDILG VCCDPLVLAQ QLTHIELDRV SSIYPEDLMQ 
       250        260        270        280        290        300 
IVSHMDSLDN HRCRGDLTKT YSLEAYDNWF NCLSMLVATE VCRVVKKKHR TRMLEFFIDV 
       310        320        330        340        350        360 
ARECFNIGNF NSMMAIISGM NLSPVARLKK TWSKVKTAKF DVLEHHMDPS SNFCNYRTAL 
       370        380        390        400        410        420 
QGATQRSQMA NSSREKIVIP VFNLFVKDIY FLHKIHTNHL PNGHINFKKF WEISRQIHEF 
       430        440        450        460        470        480 
MTWTQVECPF EKDKKIQSYL LTAPIYSEEA LFVASFESEG PENHMEKDSW KTLRTTLLNR 
   
A



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8N9B8-1-unknown MPQTSV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8N9B8-1-unknown MPQTSV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt95845

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLNRA 481 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LLNRA 481 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt83032

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)