TopFIND 4.0

Q8NA58: Poly(A)-specific ribonuclease PNLDC1 {ECO:0000305}

General Information

Protein names
- Poly(A)-specific ribonuclease PNLDC1 {ECO:0000305}
- 3.1.13.4 {ECO:0000269|PubMed:27515512}
- PARN-like domain-containing protein 1 {ECO:0000312|HGNC:HGNC:21185}
- Poly(A)-specific ribonuclease domain-containing protein 1 {ECO:0000312|HGNC:HGNC:21185}
- HsPNLDC1 {ECO:0000303|PubMed:27515512}
Gene names PNLDC1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NA58

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFCTRGLLFF AFLAGLDIEF TGLRSNLSGP QQISLFDLPS EWYLKTRQSV QQFTVCQIGL 
        70         80         90        100        110        120 
SVFSAIEGEA NKYIAHSCNF YLFPTTFGIL DSEFSFQASS VQFLNQYGFN YNKFLKNGIP 
       130        140        150        160        170        180 
YMNEEQEKKI RHDILTGNWR VRSSPDKDQI KVVIDEVTRW LELAKEGDWM TLPGITGFQA 
       190        200        210        220        230        240 
FEVQLVLRQA LPNIWTVLKD EGVVVKKVSK QHRWYLQNTS CDRESCWKEN ILLSARGFSV 
       250        260        270        280        290        300 
FFQMLVKAQK PLVGHNMMMD LLHLHEKFFR PLPESYDQFK QNIHSLFPVL IDTKSVTKDI 
       310        320        330        340        350        360 
WKEMNFPRVS NLSEVYEVLN SDLNPTKNSG PEIVHASRCE KYVETKCPHE AAYDAFLCGS 
       370        380        390        400        410        420 
VLLKVAHLLL QKIYHIDPVP ESSFPQYLDV LAPYVNQVNL IRAGVPKINF SGPDYPSIRP 
       430        440        450        460        470        480 
PILILSVKRW PGVSEQQVYH KFQNLCKFDV RRLTRSQFLL LTNKFKDARN ILKEYRDHPT 
       490        500        510        520    
LCISLYRYWR HSPNVNCLLQ VCGIVTAWAL LAFILGRSGT 

Isoforms

- Isoform 2 of Poly(A)-specific ribonuclease PARN-like domain-containing protein 1 - Isoform 2 of Poly(A)-specific ribonuclease PNLDC1

Sequence View

        10         20         30         40         50         60 
MFCTRGLLFF AFLAGLDIEF TGLRSNLSGP QQISLFDLPS EWYLKTRQSV QQFTVCQIGL 
        70         80         90        100        110        120 
SVFSAIEGEA NKYIAHSCNF YLFPTTFGIL DSEFSFQASS VQFLNQYGFN YNKFLKNGIP 
       130        140        150        160        170        180 
YMNEEQEKKI RHDILTGNWR VRSSPDKDQI KVVIDEVTRW LELAKEGDWM TLPGITGFQA 
       190        200        210        220        230        240 
FEVQLVLRQA LPNIWTVLKD EGVVVKKVSK QHRWYLQNTS CDRESCWKEN ILLSARGFSV 
       250        260        270        280        290        300 
FFQMLVKAQK PLVGHNMMMD LLHLHEKFFR PLPESYDQFK QNIHSLFPVL IDTKSVTKDI 
       310        320        330        340        350        360 
WKEMNFPRVS NLSEVYEVLN SDLNPTKNSG PEIVHASRCE KYVETKCPHE AAYDAFLCGS 
       370        380        390        400        410        420 
VLLKVAHLLL QKIYHIDPVP ESSFPQYLDV LAPYVNQVNL IRAGVPKINF SGPDYPSIRP 
       430        440        450        460        470        480 
PILILSVKRW PGVSEQQVYH KFQNLCKFDV RRLTRSQFLL LTNKFKDARN ILKEYRDHPT 
       490        500        510        520    
LCISLYRYWR HSPNVNCLLQ VCGIVTAWAL LAFILGRSGT          10         20         30         40         50         60 
MFCTRGLLFF AFLAGLDIEF TGLRSNLSGP QQISLFDLPS EWYLKTRQSV QQFTVCQIGL 
        70         80         90        100        110        120 
SVFSAIEGEA NKYIAHSCNF YLFPTTFGIL DSEFSFQASS VQFLNQYGFN YNKFLKNGIP 
       130        140        150        160        170        180 
YMNEEQEKKI RHDILTGNWR VRSSPDKDQI KVVIDEVTRW LELAKEGDWM TLPGITGFQA 
       190        200        210        220        230        240 
FEVQLVLRQA LPNIWTVLKD EGVVVKKVSK QHRWYLQNTS CDRESCWKEN ILLSARGFSV 
       250        260        270        280        290        300 
FFQMLVKAQK PLVGHNMMMD LLHLHEKFFR PLPESYDQFK QNIHSLFPVL IDTKSVTKDI 
       310        320        330        340        350        360 
WKEMNFPRVS NLSEVYEVLN SDLNPTKNSG PEIVHASRCE KYVETKCPHE AAYDAFLCGS 
       370        380        390        400        410        420 
VLLKVAHLLL QKIYHIDPVP ESSFPQYLDV LAPYVNQVNL IRAGVPKINF SGPDYPSIRP 
       430        440        450        460        470        480 
PILILSVKRW PGVSEQQVYH KFQNLCKFDV RRLTRSQFLL LTNKFKDARN ILKEYRDHPT 
       490        500        510        520    
LCISLYRYWR HSPNVNCLLQ VCGIVTAWAL LAFILGRSGT 



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NA58-19-unknown EFTGLR... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8NA58-19-unknown EFTGLR... 19 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112206

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GRSGT 520 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GRSGT 520 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt81308

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)