Q8NB66: Protein unc-13 homolog C

General Information

Protein names	- Protein unc-13 homolog C - Munc13-3
Gene names	UNC13C
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8NB66

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVANFFKSLI LPYIHKLCKG MFTKKLGNTN KNKEYRQQKK DQDFPTAGQT KSPKFSYTFK
        70         80         90        100        110        120
STVKKIAKCS STHNLSTEED EASKEFSLSP TFSYRVAIAN GLQKNAKVTN SDNEDLLQEL
       130        140        150        160        170        180
SSIESSYSES LNELRSSTEN QAQSTHTMPV RRNRKSSSSL APSEGSSDGE RTLHGLKLGA
       190        200        210        220        230        240
LRKLRKWKKS QECVSSDSEL STMKKSWGIR SKSLDRTVRN PKTNALEPGF SSSGCISQTH
       250        260        270        280        290        300
DVMEMIFKEL QGISQIETEL SELRGHVNAL KHSIDEISSS VEVVQSEIEQ LRTGFVQSRR
       310        320        330        340        350        360
ETRDIHDYIK HLGHMGSKAS LRFLNVTEER FEYVESVVYQ ILIDKMGFSD APNAIKIEFA
       370        380        390        400        410        420
QRIGHQRDCP NAKPRPILVY FETPQQRDSV LKKSYKLKGT GIGISTDILT HDIRERKEKG
       430        440        450        460        470        480
IPSSQTYESM AIKLSTPEPK IKKNNWQSPD DSDEDLESDL NRNSYAVLSK SELLTKGSTS
       490        500        510        520        530        540
KPSSKSHSAR SKNKTANSSR ISNKSDYDKI SSQLPESDIL EKQTTTHYAD ATPLWHSQSD
       550        560        570        580        590        600
FFTAKLSRSE SDFSKLCQSY SEDFSENQFF TRTNGSSLLS SSDRELWQRK QEGTATLYDS
       610        620        630        640        650        660
PKDQHLNGGV QGIQGQTETE NTETVDSGMS NGMVCASGDR SHYSDSQLSL HEDLSPWKEW
       670        680        690        700        710        720
NQGADLGLDS STQEGFDYET NSLFDQQLDV YNKDLEYLGK CHSDLQDDSE SYDLTQDDNS
       730        740        750        760        770        780
SPCPGLDNEP QGQWVGQYDS YQGANSNELY QNQNQLSMMY RSQSELQSDD SEDAPPKSWH
       790        800        810        820        830        840
SRLSIDLSDK TFSFPKFGST LQRAKSALEV VWNKSTQSLS GYEDSGSSLM GRFRTLSQST
       850        860        870        880        890        900
ANESSTTLDS DVYTEPYYYK AEDEEDYTEP VADNETDYVE VMEQVLAKLE NRTSITETDE
       910        920        930        940        950        960
QMQAYDHLSY ETPYETPQDE GYDGPADDMV SEEGLEPLNE TSAEMEIRED ENQNIPEQPV
       970        980        990       1000       1010       1020
EITKPKRIRP SFKEAALRAY KKQMAELEEK ILAGDSSSVD EKARIVSGND LDASKFSALQ
      1030       1040       1050       1060       1070       1080
VCGGAGGGLY GIDSMPDLRR KKTLPIVRDV AMTLAARKSG LSLAMVIRTS LNNEELKMHV
      1090       1100       1110       1120       1130       1140
FKKTLQALIY PMSSTIPHNF EVWTATTPTY CYECEGLLWG IARQGMKCLE CGVKCHEKCQ
      1150       1160       1170       1180       1190       1200
DLLNADCLQR AAEKSSKHGA EDKTQTIITA MKERMKIREK NRPEVFEVIQ EMFQISKEDF
      1210       1220       1230       1240       1250       1260
VQFTKAAKQS VLDGTSKWSA KITITVVSAQ GLQAKDKTGS SDPYVTVQVG KNKRRTKTIF
      1270       1280       1290       1300       1310       1320
GNLNPVWDEK FYFECHNSTD RIKVRVWDED DDIKSRVKQH FKKESDDFLG QTIVEVRTLS
      1330       1340       1350       1360       1370       1380
GEMDVWYNLE KRTDKSAVSG AIRLKINVEI KGEEKVAPYH IQYTCLHENL FHYLTEVKSN
      1390       1400       1410       1420       1430       1440
GGVKIPEVKG DEAWKVFFDD ASQEIVDEFA MRYGIESIYQ AMTHFSCLSS KYMCPGVPAV
      1450       1460       1470       1480       1490       1500
MSTLLANINA FYAHTTVSTN IQVSASDRFA ATNFGREKFI KLLDQLHNSL RIDLSKYREN
      1510       1520       1530       1540       1550       1560
FPASNTERLQ DLKSTVDLLT SITFFRMKVL ELQSPPKASM VVKDCVRACL DSTYKYIFDN
      1570       1580       1590       1600       1610       1620
CHELYSQLTD PSKKQDIPRE DQGPTTKNLD FWPQLITLMV TIIDEDKTAY TPVLNQFPQE
      1630       1640       1650       1660       1670       1680
LNMGKISAEI MWTLFALDMK YALEEHENQR LCKSTDYMNL HFKVKWFYNE YVRELPAFKD
      1690       1700       1710       1720       1730       1740
AVPEYSLWFE PFVMQWLDEN EDVSMEFLHG ALGRDKKDGF QQTSEHALFS CSVVDVFAQL
      1750       1760       1770       1780       1790       1800
NQSFEIIKKL ECPNPEALSH LMRRFAKTIN KVLLQYAAIV SSDFSSHCDK ENVPCILMNN
      1810       1820       1830       1840       1850       1860
IQQLRVQLEK MFESMGGKEL DSEASTILKE LQVKLSGVLD ELSVTYGESF QVIIEECIKQ
      1870       1880       1890       1900       1910       1920
MSFELNQMRA NGNTTSNKNS AAMDAEIVLR SLMDFLDKTL SLSAKICEKT VLKRVLKELW
      1930       1940       1950       1960       1970       1980
KLVLNKIEKQ IVLPPLTDQT GPQMIFIAAK DLGQLSKLKE HMIREDARGL TPRQCAIMEV
      1990       2000       2010       2020       2030       2040
VLATIKQYFH AGGNGLKKNF LEKSPDLQSL RYALSLYTQT TDALIKKFID TQTSQSRSSK
      2050       2060       2070       2080       2090       2100
DAVGQISVHV DITATPGTGD HKVTVKVIAI NDLNWQTTAM FRPFVEVCIL GPNLGDKKRK
      2110       2120       2130       2140       2150       2160
QGTKTKSNTW SPKYNETFQF ILGKENRPGA YELHLSVKDY CFAREDRIIG MTVIQLQNIA
      2170       2180       2190       2200       2210
EKGSYGAWYP LLKNISMDET GLTILRILSQ RTSDDVAKEF VRLKSETRST EESA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8NB66-1-unknown	MVANFF...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8NB66-2080-unknown	MFRPFV...	2080	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000443886
Q8NB66-2080-unknown	MFRPFV...	2080	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456350

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EKQIVL	1932	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453018
...GDKKRK	2099	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456350
...TEESA	2214	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)