TopFIND 4.0

Q8NBR6: Ubiquitin carboxyl-terminal hydrolase MINDY-2 {ECO:0000303|PubMed:27292798}

General Information

Protein names
- Ubiquitin carboxyl-terminal hydrolase MINDY-2 {ECO:0000303|PubMed:27292798}
- 3.4.19.12 {ECO:0000269|PubMed:27292798}
- Deubiquitinating enzyme MINDY-2 {ECO:0000303|PubMed:27292798}
- Protein FAM63B
Gene names FAM63B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NBR6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MESSPESLQP LEHGVAAGPA SGTGSSQEGL QETRLAAGDG PGVWAAETSG GNGLGAAAAR 
        70         80         90        100        110        120 
RSLPDSASPA GSPEVPGPCS SSAGLDLKDS GLESPAAAEA PLRGQYKVTA SPETAVAGVG 
       130        140        150        160        170        180 
HELGTAGDAG ARPDLAGTCQ AELTAAGSEE PSSAGGLSSS CSDPSPPGES PSLDSLESFS 
       190        200        210        220        230        240 
NLHSFPSSCE FNSEEGAENR VPEEEEGAAV LPGAVPLCKE EEGEETAQVL AASKERFPGQ 
       250        260        270        280        290        300 
SVYHIKWIQW KEENTPIITQ NENGPCPLLA ILNVLLLAWK VKLPPMMEII TAEQLMEYLG 
       310        320        330        340        350        360 
DYMLDAKPKE ISEIQRLNYE QNMSDAMAIL HKLQTGLDVN VRFTGVRVFE YTPECIVFDL 
       370        380        390        400        410        420 
LDIPLYHGWL VDPQIDDIVK AVGNCSYNQL VEKIISCKQS DNSELVSEGF VAEQFLNNTA 
       430        440        450        460        470        480 
TQLTYHGLCE LTSTVQEGEL CVFFRNNHFS TMTKYKGQLY LLVTDQGFLT EEKVVWESLH 
       490        500        510        520        530        540 
NVDGDGNFCD SEFHLRPPSD PETVYKGQQD QIDQDYLMAL SLQQEQQSQE INWEQIPEGI 
       550        560        570        580        590        600 
SDLELAKKLQ EEEDRRASQY YQEQEQAAAA AAAASTQAQQ GQPAQASPSS GRQSGNSERK 
       610        620    
RKEPREKDKE KEKEKNSCVI L

Isoforms

- Isoform 2 of Protein FAM63B - Isoform 2 of Ubiquitin carboxyl-terminal hydrolase MINDY-2

Sequence View

        10         20         30         40         50         60 
MESSPESLQP LEHGVAAGPA SGTGSSQEGL QETRLAAGDG PGVWAAETSG GNGLGAAAAR 
        70         80         90        100        110        120 
RSLPDSASPA GSPEVPGPCS SSAGLDLKDS GLESPAAAEA PLRGQYKVTA SPETAVAGVG 
       130        140        150        160        170        180 
HELGTAGDAG ARPDLAGTCQ AELTAAGSEE PSSAGGLSSS CSDPSPPGES PSLDSLESFS 
       190        200        210        220        230        240 
NLHSFPSSCE FNSEEGAENR VPEEEEGAAV LPGAVPLCKE EEGEETAQVL AASKERFPGQ 
       250        260        270        280        290        300 
SVYHIKWIQW KEENTPIITQ NENGPCPLLA ILNVLLLAWK VKLPPMMEII TAEQLMEYLG 
       310        320        330        340        350        360 
DYMLDAKPKE ISEIQRLNYE QNMSDAMAIL HKLQTGLDVN VRFTGVRVFE YTPECIVFDL 
       370        380        390        400        410        420 
LDIPLYHGWL VDPQIDDIVK AVGNCSYNQL VEKIISCKQS DNSELVSEGF VAEQFLNNTA 
       430        440        450        460        470        480 
TQLTYHGLCE LTSTVQEGEL CVFFRNNHFS TMTKYKGQLY LLVTDQGFLT EEKVVWESLH 
       490        500        510        520        530        540 
NVDGDGNFCD SEFHLRPPSD PETVYKGQQD QIDQDYLMAL SLQQEQQSQE INWEQIPEGI 
       550        560        570        580        590        600 
SDLELAKKLQ EEEDRRASQY YQEQEQAAAA AAAASTQAQQ GQPAQASPSS GRQSGNSERK 
       610        620    
RKEPREKDKE KEKEKNSCVI L         10         20         30         40         50         60 
MESSPESLQP LEHGVAAGPA SGTGSSQEGL QETRLAAGDG PGVWAAETSG GNGLGAAAAR 
        70         80         90        100        110        120 
RSLPDSASPA GSPEVPGPCS SSAGLDLKDS GLESPAAAEA PLRGQYKVTA SPETAVAGVG 
       130        140        150        160        170        180 
HELGTAGDAG ARPDLAGTCQ AELTAAGSEE PSSAGGLSSS CSDPSPPGES PSLDSLESFS 
       190        200        210        220        230        240 
NLHSFPSSCE FNSEEGAENR VPEEEEGAAV LPGAVPLCKE EEGEETAQVL AASKERFPGQ 
       250        260        270        280        290        300 
SVYHIKWIQW KEENTPIITQ NENGPCPLLA ILNVLLLAWK VKLPPMMEII TAEQLMEYLG 
       310        320        330        340        350        360 
DYMLDAKPKE ISEIQRLNYE QNMSDAMAIL HKLQTGLDVN VRFTGVRVFE YTPECIVFDL 
       370        380        390        400        410        420 
LDIPLYHGWL VDPQIDDIVK AVGNCSYNQL VEKIISCKQS DNSELVSEGF VAEQFLNNTA 
       430        440        450        460        470        480 
TQLTYHGLCE LTSTVQEGEL CVFFRNNHFS TMTKYKGQLY LLVTDQGFLT EEKVVWESLH 
       490        500        510        520        530        540 
NVDGDGNFCD SEFHLRPPSD PETVYKGQQD QIDQDYLMAL SLQQEQQSQE INWEQIPEGI 
       550        560        570        580        590        600 
SDLELAKKLQ EEEDRRASQY YQEQEQAAAA AAAASTQAQQ GQPAQASPSS GRQSGNSERK 
       610        620    
RKEPREKDKE KEKEKNSCVI L



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NBR6-1-unknown MESSPE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8NBR6-1-unknown MESSPE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74646

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SCVIL 621 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SCVIL 621 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt70264

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)