TopFIND 4.0

Q8NC56: LEM domain-containing protein 2

General Information

Protein names
- LEM domain-containing protein 2
- hLEM2
Gene names LEMD2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NC56

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGLSDLELR RELQALGFQP GPITDTTRDV YRNKLRRLRG EARLRDEERL REEARPRGEE 
        70         80         90        100        110        120 
RLREEARLRE DAPLRARPAA ASPRAEPWLS QPASGSAYAT PGAYGDIRPS AASWVGSRGL 
       130        140        150        160        170        180 
AYPARPAQLR RRASVRGSSE EDEDARTPDR ATQGPGLAAR RWWAASPAPA RLPSSLLGPD 
       190        200        210        220        230        240 
PRPGLRATRA GPAGAARARP EVGRRLERWL SRLLLWASLG LLLVFLGILW VKMGKPSAPQ 
       250        260        270        280        290        300 
EAEDNMKLLP VDCERKTDEF CQAKQKAALL ELLHELYNFL AIQAGNFECG NPENLKSKCI 
       310        320        330        340        350        360 
PVMEAQEYIA NVTSSSSAKF EAALTWILSS NKDVGIWLKG EDQSELVTTV DKVVCLESAH 
       370        380        390        400        410        420 
PRMGVGCRLS RALLTAVTNV LIFFWCLAFL WGLLILLKYR WRKLEEEEQA MYEMVKKIID 
       430        440        450        460        470        480 
VVQDHYVDWE QDMERYPYVG ILHVRDSLIP PQSRRRMKRV WDRAVEFLAS NESRIQTESH 
       490        500    
RVAGEDMLVW RWTKPSSFSD SER

Isoforms

- Isoform 2 of LEM domain-containing protein 2

Sequence View

        10         20         30         40         50         60 
MAGLSDLELR RELQALGFQP GPITDTTRDV YRNKLRRLRG EARLRDEERL REEARPRGEE 
        70         80         90        100        110        120 
RLREEARLRE DAPLRARPAA ASPRAEPWLS QPASGSAYAT PGAYGDIRPS AASWVGSRGL 
       130        140        150        160        170        180 
AYPARPAQLR RRASVRGSSE EDEDARTPDR ATQGPGLAAR RWWAASPAPA RLPSSLLGPD 
       190        200        210        220        230        240 
PRPGLRATRA GPAGAARARP EVGRRLERWL SRLLLWASLG LLLVFLGILW VKMGKPSAPQ 
       250        260        270        280        290        300 
EAEDNMKLLP VDCERKTDEF CQAKQKAALL ELLHELYNFL AIQAGNFECG NPENLKSKCI 
       310        320        330        340        350        360 
PVMEAQEYIA NVTSSSSAKF EAALTWILSS NKDVGIWLKG EDQSELVTTV DKVVCLESAH 
       370        380        390        400        410        420 
PRMGVGCRLS RALLTAVTNV LIFFWCLAFL WGLLILLKYR WRKLEEEEQA MYEMVKKIID 
       430        440        450        460        470        480 
VVQDHYVDWE QDMERYPYVG ILHVRDSLIP PQSRRRMKRV WDRAVEFLAS NESRIQTESH 
       490        500    
RVAGEDMLVW RWTKPSSFSD SER



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SDSER 503 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SDSER 503 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt75124

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)