TopFIND 4.0

Q8NCC3: Group XV phospholipase A2

General Information

Protein names
- Group XV phospholipase A2
- 2.3.1.- {ECO:0000269|PubMed:11790796, ECO:0000269|PubMed:20410020, ECO:0000269|PubMed:23958596, ECO:0000269|PubMed:25727495}
- 1-O-acylceramide synthase {ECO:0000303|PubMed:11790796}
- ACS
- LCAT-like lysophospholipase {ECO:0000303|PubMed:10092508}
- LLPL {ECO:0000303|PubMed:10092508}
- Lysophospholipase 3
- Lysosomal phospholipase A2 {ECO:0000303|PubMed:11790796, ECO:0000303|PubMed:23958596}
- LPLA2 {ECO:0000303|PubMed:11790796, ECO:0000303|PubMed:23958596}
Gene names PLA2G15
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NCC3

1

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGLHLRPYRV GLLPDGLLFL LLLLMLLADP ALPAGRHPPV VLVPGDLGNQ LEAKLDKPTV 
        70         80         90        100        110        120 
VHYLCSKKTE SYFTIWLNLE LLLPVIIDCW IDNIRLVYNK TSRATQFPDG VDVRVPGFGK 
       130        140        150        160        170        180 
TFSLEFLDPS KSSVGSYFHT MVESLVGWGY TRGEDVRGAP YDWRRAPNEN GPYFLALREM 
       190        200        210        220        230        240 
IEEMYQLYGG PVVLVAHSMG NMYTLYFLQR QPQAWKDKYI RAFVSLGAPW GGVAKTLRVL 
       250        260        270        280        290        300 
ASGDNNRIPV IGPLKIREQQ RSAVSTSWLL PYNYTWSPEK VFVQTPTINY TLRDYRKFFQ 
       310        320        330        340        350        360 
DIGFEDGWLM RQDTEGLVEA TMPPGVQLHC LYGTGVPTPD SFYYESFPDR DPKICFGDGD 
       370        380        390        400        410    
GTVNLKSALQ CQAWQSRQEH QVLLQELPGS EHIEMLANAT TLAYLKRVLL GP

Isoforms

- Isoform 2 of Group XV phospholipase A2

Sequence View

        10         20         30         40         50         60 
MGLHLRPYRV GLLPDGLLFL LLLLMLLADP ALPAGRHPPV VLVPGDLGNQ LEAKLDKPTV 
        70         80         90        100        110        120 
VHYLCSKKTE SYFTIWLNLE LLLPVIIDCW IDNIRLVYNK TSRATQFPDG VDVRVPGFGK 
       130        140        150        160        170        180 
TFSLEFLDPS KSSVGSYFHT MVESLVGWGY TRGEDVRGAP YDWRRAPNEN GPYFLALREM 
       190        200        210        220        230        240 
IEEMYQLYGG PVVLVAHSMG NMYTLYFLQR QPQAWKDKYI RAFVSLGAPW GGVAKTLRVL 
       250        260        270        280        290        300 
ASGDNNRIPV IGPLKIREQQ RSAVSTSWLL PYNYTWSPEK VFVQTPTINY TLRDYRKFFQ 
       310        320        330        340        350        360 
DIGFEDGWLM RQDTEGLVEA TMPPGVQLHC LYGTGVPTPD SFYYESFPDR DPKICFGDGD 
       370        380        390        400        410    
GTVNLKSALQ CQAWQSRQEH QVLLQELPGS EHIEMLANAT TLAYLKRVLL GP



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NCC3-34-unknown AGRHPP... 34 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)