Q8ND25: E3 ubiquitin-protein ligase ZNRF1

General Information

Protein names	- E3 ubiquitin-protein ligase ZNRF1 - 2.3.2.27 - Nerve injury-induced gene 283 protein - RING-type E3 ubiquitin transferase ZNRF1 - Zinc/RING finger protein 1
Gene names	ZNRF1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8ND25

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGGKQSTAAR SRGPFPGVST DDSAVPPPGG APHFGHYRTG GGAMGLRSRS VSSVAGMGMD
        70         80         90        100        110        120
PSTAGGVPFG LYTPASRGTG DSERAPGGGG SASDSTYAHG NGYQETGGGH HRDGMLYLGS
       130        140        150        160        170        180
RASLADALPL HIAPRWFSSH SGFKCPICSK SVASDEMEMH FIMCLSKPRL SYNDDVLTKD
       190        200        210        220
AGECVICLEE LLQGDTIARL PCLCIYHKSC IDSWFEVNRS CPEHPAD

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase ZNRF1

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8ND25-1-unknown	MGGKQS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt95636
Q8ND25-2-unknown	GGKQST...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8ND25-2-unknown	GGKQST...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110329
Q8ND25-127-unknown	ALPLHI...	127		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q8ND25-127-unknown	ALPLHI...	127	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160421
Q8ND25-127-	ALPLHI...	127		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...EHPAD	227	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...EHPAD	227	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt91254

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)