TopFIND 4.0

Q8NDH6: Islet cell autoantigen 1-like protein

General Information

Protein names
- Islet cell autoantigen 1-like protein
- Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein
- Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein
Gene names ICA1L
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NDH6

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDSFGQPRPE DNQSVVRRMQ KKYWKTKQVF IKATGKKEDE HLVASDAELD AKLEVFHSVQ 
        70         80         90        100        110        120 
ETCTELLKII EKYQLRLNVI SEEENELGLF LKFQAERDAT QAGKMMDATG KALCSSAKQR 
       130        140        150        160        170        180 
LALCTPLSRL KQEVATFSQR AVSDTLMTIN RMEQARTEYR GALLWMKDVS QELDPDTLKQ 
       190        200        210        220        230        240 
MEKFRKVQMQ VRNSKASFDK LKMDVCQKVD LLGASRCNML SHSLTTYQRT LLGFWKKTAR 
       250        260        270        280        290        300 
MMSQIHEACI GFHPYDFVAL KQLQDTPSKI SEDNKDEQIG GFLTEQLNKL VLSDEEASFE 
       310        320        330        340        350        360 
SEQANKDHNE KHSQMREFGA PQFSNSENVA KDLPVDSLEG EDFEKEFSFL NNLLSSGSSS 
       370        380        390        400        410        420 
TSEFTQECQT AFGSPSASLT SQEPSMGSEP LAHSSRFLPS QLFDLGFHVA GAFNNWVSQE 
       430        440        450        460        470        480 
ESELCLSHTD NQPVPSQSPK KLTRSPNNGN QDMSAWFNLF ADLDPLSNPD AIGHSDDELL 
   
NA

Isoforms

- Isoform 2 of Islet cell autoantigen 1-like protein

Sequence View

        10         20         30         40         50         60 
MDSFGQPRPE DNQSVVRRMQ KKYWKTKQVF IKATGKKEDE HLVASDAELD AKLEVFHSVQ 
        70         80         90        100        110        120 
ETCTELLKII EKYQLRLNVI SEEENELGLF LKFQAERDAT QAGKMMDATG KALCSSAKQR 
       130        140        150        160        170        180 
LALCTPLSRL KQEVATFSQR AVSDTLMTIN RMEQARTEYR GALLWMKDVS QELDPDTLKQ 
       190        200        210        220        230        240 
MEKFRKVQMQ VRNSKASFDK LKMDVCQKVD LLGASRCNML SHSLTTYQRT LLGFWKKTAR 
       250        260        270        280        290        300 
MMSQIHEACI GFHPYDFVAL KQLQDTPSKI SEDNKDEQIG GFLTEQLNKL VLSDEEASFE 
       310        320        330        340        350        360 
SEQANKDHNE KHSQMREFGA PQFSNSENVA KDLPVDSLEG EDFEKEFSFL NNLLSSGSSS 
       370        380        390        400        410        420 
TSEFTQECQT AFGSPSASLT SQEPSMGSEP LAHSSRFLPS QLFDLGFHVA GAFNNWVSQE 
       430        440        450        460        470        480 
ESELCLSHTD NQPVPSQSPK KLTRSPNNGN QDMSAWFNLF ADLDPLSNPD AIGHSDDELL 
   
NA



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NDH6-1-unknown MDSFGQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8NDH6-1-unknown MDSFGQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77465

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KFRKVQ 187 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73083
    ...ELLNA 482 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)