TopFIND 4.0

Q8NDZ4: Divergent protein kinase domain 2A {ECO:0000305}

General Information

Protein names
- Divergent protein kinase domain 2A {ECO:0000305}
- Deleted in autism protein 1 {ECO:0000303|PubMed:18621663}
- Golgi Protein of 49 kDa {ECO:0000303|PubMed:18651652}
- GoPro49 {ECO:0000303|PubMed:18651652}
- Hypoxia and AKT-induced stem cell factor
- HASF
Gene names C3orf58
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NDZ4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MWRLVPPKLG RLSRSLKLAA LGSLLVLMVL HSPSLLASWQ RNELTDRRFL QLNKCPACFG 
        70         80         90        100        110        120 
TSWCRRFLNG QVVFEAWGRL RLLDFLNVKN VYFAQYGEPR EGGRRRVVLK RLGSQRELAQ 
       130        140        150        160        170        180 
LDQSICKRAT GRPRCDLLQA MPRTEFARLN GDVRLLTPEA VEGWSDLVHC PSQRLLDRLV 
       190        200        210        220        230        240 
RRYAETKDSG SFLLRNLKDS ERMQLLLTLA FNPEPLVLQS FPSDEGWPFA KYLGACGRMV 
       250        260        270        280        290        300 
AVNYVGEELW SYFNAPWEKR VDLAWQLMEI AEQLTNNDFE FALYLLDVSF DNFAVGPRDG 
       310        320        330        340        350        360 
KVIIVDAENV LVADKRLIRQ NKPENWDVWY ESKFDDCDKE ACLSFSKEIL CARATVDHNY 
       370        380        390        400        410        420 
YAVCQNLLSR HATWRGTSGG LLHDPPSEIA KDGRLEALLD ECANPKKRYG RFQAAKELRE 
       430    
YLAQLSNNVR 

Isoforms

- Isoform 2 of Deleted in autism protein 1 - Isoform 2 of Divergent protein kinase domain 2A

Sequence View

        10         20         30         40         50         60 
MWRLVPPKLG RLSRSLKLAA LGSLLVLMVL HSPSLLASWQ RNELTDRRFL QLNKCPACFG 
        70         80         90        100        110        120 
TSWCRRFLNG QVVFEAWGRL RLLDFLNVKN VYFAQYGEPR EGGRRRVVLK RLGSQRELAQ 
       130        140        150        160        170        180 
LDQSICKRAT GRPRCDLLQA MPRTEFARLN GDVRLLTPEA VEGWSDLVHC PSQRLLDRLV 
       190        200        210        220        230        240 
RRYAETKDSG SFLLRNLKDS ERMQLLLTLA FNPEPLVLQS FPSDEGWPFA KYLGACGRMV 
       250        260        270        280        290        300 
AVNYVGEELW SYFNAPWEKR VDLAWQLMEI AEQLTNNDFE FALYLLDVSF DNFAVGPRDG 
       310        320        330        340        350        360 
KVIIVDAENV LVADKRLIRQ NKPENWDVWY ESKFDDCDKE ACLSFSKEIL CARATVDHNY 
       370        380        390        400        410        420 
YAVCQNLLSR HATWRGTSGG LLHDPPSEIA KDGRLEALLD ECANPKKRYG RFQAAKELRE 
       430    
YLAQLSNNVR          10         20         30         40         50         60 
MWRLVPPKLG RLSRSLKLAA LGSLLVLMVL HSPSLLASWQ RNELTDRRFL QLNKCPACFG 
        70         80         90        100        110        120 
TSWCRRFLNG QVVFEAWGRL RLLDFLNVKN VYFAQYGEPR EGGRRRVVLK RLGSQRELAQ 
       130        140        150        160        170        180 
LDQSICKRAT GRPRCDLLQA MPRTEFARLN GDVRLLTPEA VEGWSDLVHC PSQRLLDRLV 
       190        200        210        220        230        240 
RRYAETKDSG SFLLRNLKDS ERMQLLLTLA FNPEPLVLQS FPSDEGWPFA KYLGACGRMV 
       250        260        270        280        290        300 
AVNYVGEELW SYFNAPWEKR VDLAWQLMEI AEQLTNNDFE FALYLLDVSF DNFAVGPRDG 
       310        320        330        340        350        360 
KVIIVDAENV LVADKRLIRQ NKPENWDVWY ESKFDDCDKE ACLSFSKEIL CARATVDHNY 
       370        380        390        400        410        420 
YAVCQNLLSR HATWRGTSGG LLHDPPSEIA KDGRLEALLD ECANPKKRYG RFQAAKELRE 
       430    
YLAQLSNNVR 



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NDZ4-36-unknown LASWQR... 36 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SNNVR 430 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SNNVR 430 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt68393

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)