Q8NE09: Regulator of G-protein signaling 22

General Information

Protein names	- Regulator of G-protein signaling 22 - RGS22
Gene names	RGS22
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8NE09

3 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEKRLTAEP PTITEEEFED SLATDDFLVD YFNEFLSLPT FSEAIRFNAD YGVFEVANDA
        70         80         90        100        110        120
PQFLEKQLKK ILQNQQPRNP IYDVVRKGKN EVKPVQMNAP DEDETINVNY NIMCLSREEG
       130        140        150        160        170        180
IKWIKKERLP AFLESDCYFE YRLAKLVSQV RWSKSGMNFT VGSNFSPWIV KKPPSLPPPA
       190        200        210        220        230        240
TEEDNLVIMK KFYVSLGEAS YTQTKDWFAL AKQSQQTVST FSLPCCVPYN KLKSPAISSV
       250        260        270        280        290        300
SENFIFDDGV HPRTKKDPSK TNKLISEFEE EEGEEEEVSV SLQDTPSQAL LRVYLEKKQD
       310        320        330        340        350        360
VDESLTMHFS TCEEFLSSYI YFILRGAIQQ IVGKPVGETP DYINFNNITK VSFDDCFESI
       370        380        390        400        410        420
HGKNFLSELV QTTKERSEEI EQTSLSSKNE SAGPESRADW CISHRTYDIG NRKEFERFKK
       430        440        450        460        470        480
FIKGTLGERY WWLWMDIERL KVLKDPGRHQ RHLEKMKKCY LVSNGDYYLS AEILSKFKLL
       490        500        510        520        530        540
DGSQWNEEHL RNIQSEVLKP LLLYWAPRFC VTHSASTKYA SAELKFWHLR QAKPRKDIDP
       550        560        570        580        590        600
FPQMATLLPL RPKSCIPQIP EIQKEEFSLS QPPKSPNKSP EVKTATQKPW KRELLYPGSS
       610        620        630        640        650        660
KDDVIEKGSK YMSESSKVIH LTSFTDISEC LKPQLDRRYA YTEEPRVKTV SDVGALGGSD
       670        680        690        700        710        720
MENLLQSLYV ENRAGFFFTK FCEHSGNKLW KNSVYFWFDL QAYHQLFYQE TLQPFKVCKQ
       730        740        750        760        770        780
AQYLFATYVA PSATLDIGLQ QEKKKEIYMK IQPPFEDLFD TAEEYILLLL LEPWTKMVKS
       790        800        810        820        830        840
DQIAYKKVEL VEETRQLDST YFRKLQALHK ETFSKKAEDT TCEIGTGILS LSNVSKRTEY
       850        860        870        880        890        900
WDNVPAEYKH FKFSDLLNNK LEFEHFRQFL ETHSSSMDLM CWTDIEQFRR ITYRDRNQRK
       910        920        930        940        950        960
AKSIYIKNKY LNKKYFFGPN SPASLYQQNQ VMHLSGGWGK ILHEQLDAPV LVEIQKHVQN
       970        980        990       1000       1010       1020
RLENVWLPLF LASEQFAARQ KIKVQMKDIA EELLLQKAEK KIGVWKPVES KWISSSCKII
      1030       1040       1050       1060       1070       1080
AFRKALLNPV TSRQFQRFVA LKGDLLENGL LFWQEVQKYK DLCHSHCDES VIQKKITTII
      1090       1100       1110       1120       1130       1140
NCFINSSIPP ALQIDIPVEQ AQKIIEHRKE LGPYVFREAQ MTIFGVLFKF WPQFCEFRKN
      1150       1160       1170       1180       1190       1200
LTDENIMSVL ERRQEYNKQK KKLAVLEDEK SGKDGIKQYA NTSVPAIKTA LLSDSFLGLQ
      1210       1220       1230       1240       1250       1260
PYGRQPTWCY SKYIEALEQE RILLKIQEEL EKKLFAGLQP LTNFKASSST MSLKKNMSAH

SSQK

Isoforms

- Isoform 2 of Regulator of G-protein signaling 22 - Isoform 3 of Regulator of G-protein signaling 22

Sequence View

        10         20         30         40         50         60
MPEKRLTAEP PTITEEEFED SLATDDFLVD YFNEFLSLPT FSEAIRFNAD YGVFEVANDA
        70         80         90        100        110        120
PQFLEKQLKK ILQNQQPRNP IYDVVRKGKN EVKPVQMNAP DEDETINVNY NIMCLSREEG
       130        140        150        160        170        180
IKWIKKERLP AFLESDCYFE YRLAKLVSQV RWSKSGMNFT VGSNFSPWIV KKPPSLPPPA
       190        200        210        220        230        240
TEEDNLVIMK KFYVSLGEAS YTQTKDWFAL AKQSQQTVST FSLPCCVPYN KLKSPAISSV
       250        260        270        280        290        300
SENFIFDDGV HPRTKKDPSK TNKLISEFEE EEGEEEEVSV SLQDTPSQAL LRVYLEKKQD
       310        320        330        340        350        360
VDESLTMHFS TCEEFLSSYI YFILRGAIQQ IVGKPVGETP DYINFNNITK VSFDDCFESI
       370        380        390        400        410        420
HGKNFLSELV QTTKERSEEI EQTSLSSKNE SAGPESRADW CISHRTYDIG NRKEFERFKK
       430        440        450        460        470        480
FIKGTLGERY WWLWMDIERL KVLKDPGRHQ RHLEKMKKCY LVSNGDYYLS AEILSKFKLL
       490        500        510        520        530        540
DGSQWNEEHL RNIQSEVLKP LLLYWAPRFC VTHSASTKYA SAELKFWHLR QAKPRKDIDP
       550        560        570        580        590        600
FPQMATLLPL RPKSCIPQIP EIQKEEFSLS QPPKSPNKSP EVKTATQKPW KRELLYPGSS
       610        620        630        640        650        660
KDDVIEKGSK YMSESSKVIH LTSFTDISEC LKPQLDRRYA YTEEPRVKTV SDVGALGGSD
       670        680        690        700        710        720
MENLLQSLYV ENRAGFFFTK FCEHSGNKLW KNSVYFWFDL QAYHQLFYQE TLQPFKVCKQ
       730        740        750        760        770        780
AQYLFATYVA PSATLDIGLQ QEKKKEIYMK IQPPFEDLFD TAEEYILLLL LEPWTKMVKS
       790        800        810        820        830        840
DQIAYKKVEL VEETRQLDST YFRKLQALHK ETFSKKAEDT TCEIGTGILS LSNVSKRTEY
       850        860        870        880        890        900
WDNVPAEYKH FKFSDLLNNK LEFEHFRQFL ETHSSSMDLM CWTDIEQFRR ITYRDRNQRK
       910        920        930        940        950        960
AKSIYIKNKY LNKKYFFGPN SPASLYQQNQ VMHLSGGWGK ILHEQLDAPV LVEIQKHVQN
       970        980        990       1000       1010       1020
RLENVWLPLF LASEQFAARQ KIKVQMKDIA EELLLQKAEK KIGVWKPVES KWISSSCKII
      1030       1040       1050       1060       1070       1080
AFRKALLNPV TSRQFQRFVA LKGDLLENGL LFWQEVQKYK DLCHSHCDES VIQKKITTII
      1090       1100       1110       1120       1130       1140
NCFINSSIPP ALQIDIPVEQ AQKIIEHRKE LGPYVFREAQ MTIFGVLFKF WPQFCEFRKN
      1150       1160       1170       1180       1190       1200
LTDENIMSVL ERRQEYNKQK KKLAVLEDEK SGKDGIKQYA NTSVPAIKTA LLSDSFLGLQ
      1210       1220       1230       1240       1250       1260
PYGRQPTWCY SKYIEALEQE RILLKIQEEL EKKLFAGLQP LTNFKASSST MSLKKNMSAH

SSQK         10         20         30         40         50         60
MPEKRLTAEP PTITEEEFED SLATDDFLVD YFNEFLSLPT FSEAIRFNAD YGVFEVANDA
        70         80         90        100        110        120
PQFLEKQLKK ILQNQQPRNP IYDVVRKGKN EVKPVQMNAP DEDETINVNY NIMCLSREEG
       130        140        150        160        170        180
IKWIKKERLP AFLESDCYFE YRLAKLVSQV RWSKSGMNFT VGSNFSPWIV KKPPSLPPPA
       190        200        210        220        230        240
TEEDNLVIMK KFYVSLGEAS YTQTKDWFAL AKQSQQTVST FSLPCCVPYN KLKSPAISSV
       250        260        270        280        290        300
SENFIFDDGV HPRTKKDPSK TNKLISEFEE EEGEEEEVSV SLQDTPSQAL LRVYLEKKQD
       310        320        330        340        350        360
VDESLTMHFS TCEEFLSSYI YFILRGAIQQ IVGKPVGETP DYINFNNITK VSFDDCFESI
       370        380        390        400        410        420
HGKNFLSELV QTTKERSEEI EQTSLSSKNE SAGPESRADW CISHRTYDIG NRKEFERFKK
       430        440        450        460        470        480
FIKGTLGERY WWLWMDIERL KVLKDPGRHQ RHLEKMKKCY LVSNGDYYLS AEILSKFKLL
       490        500        510        520        530        540
DGSQWNEEHL RNIQSEVLKP LLLYWAPRFC VTHSASTKYA SAELKFWHLR QAKPRKDIDP
       550        560        570        580        590        600
FPQMATLLPL RPKSCIPQIP EIQKEEFSLS QPPKSPNKSP EVKTATQKPW KRELLYPGSS
       610        620        630        640        650        660
KDDVIEKGSK YMSESSKVIH LTSFTDISEC LKPQLDRRYA YTEEPRVKTV SDVGALGGSD
       670        680        690        700        710        720
MENLLQSLYV ENRAGFFFTK FCEHSGNKLW KNSVYFWFDL QAYHQLFYQE TLQPFKVCKQ
       730        740        750        760        770        780
AQYLFATYVA PSATLDIGLQ QEKKKEIYMK IQPPFEDLFD TAEEYILLLL LEPWTKMVKS
       790        800        810        820        830        840
DQIAYKKVEL VEETRQLDST YFRKLQALHK ETFSKKAEDT TCEIGTGILS LSNVSKRTEY
       850        860        870        880        890        900
WDNVPAEYKH FKFSDLLNNK LEFEHFRQFL ETHSSSMDLM CWTDIEQFRR ITYRDRNQRK
       910        920        930        940        950        960
AKSIYIKNKY LNKKYFFGPN SPASLYQQNQ VMHLSGGWGK ILHEQLDAPV LVEIQKHVQN
       970        980        990       1000       1010       1020
RLENVWLPLF LASEQFAARQ KIKVQMKDIA EELLLQKAEK KIGVWKPVES KWISSSCKII
      1030       1040       1050       1060       1070       1080
AFRKALLNPV TSRQFQRFVA LKGDLLENGL LFWQEVQKYK DLCHSHCDES VIQKKITTII
      1090       1100       1110       1120       1130       1140
NCFINSSIPP ALQIDIPVEQ AQKIIEHRKE LGPYVFREAQ MTIFGVLFKF WPQFCEFRKN
      1150       1160       1170       1180       1190       1200
LTDENIMSVL ERRQEYNKQK KKLAVLEDEK SGKDGIKQYA NTSVPAIKTA LLSDSFLGLQ
      1210       1220       1230       1240       1250       1260
PYGRQPTWCY SKYIEALEQE RILLKIQEEL EKKLFAGLQP LTNFKASSST MSLKKNMSAH

SSQK

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8NE09-1-unknown	MPEKRL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8NE09-1-unknown	MPEKRL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87486
Q8NE09-1-unknown	MPEKRL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87487
Q8NE09-97-unknown	MNAPDE...	97	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000430903
Q8NE09-97-unknown	MNAPDE...	97	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427930
Q8NE09-97-unknown	MNAPDE...	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196883
Q8NE09-97-unknown	MNAPDE...	97	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196884
Q8NE09-1129-unknown	KFWPQF...	1129	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000430378
Q8NE09-1129-unknown	KFWPQF...	1129	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt200575

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PSLPPP	178	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427930
...PSLPPP	178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155360
...PSLPPP	178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155361
...ATEEDN	184	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000430903
...ATEEDN	184	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155460
...ATEEDN	184	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155461
...QSQQTV	217	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429198
...QSQQTV	217	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155780
...PLLLYW	504	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83104
...PLLLYW	504	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92955
...VLVEIQ	954	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427754
...HSSQK	1264	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HSSQK	1264	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83105

TopFIND

Q8NE09: Regulator of G-protein signaling 22

General Information

3

N-termini

6

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

3 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates