Q8NEB9: Phosphatidylinositol 3-kinase catalytic subunit type 3

General Information

Protein names	- Phosphatidylinositol 3-kinase catalytic subunit type 3 - PI3-kinase type 3 - PI3K type 3 - PtdIns-3-kinase type 3 - 2.7.1.137 - Phosphatidylinositol 3-kinase p100 subunit - Phosphoinositide-3-kinase class 3 - hVps34
Gene names	PIK3C3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8NEB9

5 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGEAEKFHYI YSCDLDINVQ LKIGSLEGKR EQKSYKAVLE DPMLKFSGLY QETCSDLYVT
        70         80         90        100        110        120
CQVFAEGKPL ALPVRTSYKA FSTRWNWNEW LKLPVKYPDL PRNAQVALTI WDVYGPGKAV
       130        140        150        160        170        180
PVGGTTVSLF GKYGMFRQGM HDLKVWPNVE ADGSEPTKTP GRTSSTLSED QMSRLAKLTK
       190        200        210        220        230        240
AHRQGHMVKV DWLDRLTFRE IEMINESEKR SSNFMYLMVE FRCVKCDDKE YGIVYYEKDG
       250        260        270        280        290        300
DESSPILTSF ELVKVPDPQM SMENLVESKH HKLARSLRSG PSDHDLKPNA ATRDQLNIIV
       310        320        330        340        350        360
SYPPTKQLTY EEQDLVWKFR YYLTNQEKAL TKFLKCVNWD LPQEAKQALE LLGKWKPMDV
       370        380        390        400        410        420
EDSLELLSSH YTNPTVRRYA VARLRQADDE DLLMYLLQLV QALKYENFDD IKNGLEPTKK
       430        440        450        460        470        480
DSQSSVSENV SNSGINSAEI DSSQIITSPL PSVSSPPPAS KTKEVPDGEN LEQDLCTFLI
       490        500        510        520        530        540
SRACKNSTLA NYLYWYVIVE CEDQDTQQRD PKTHEMYLNV MRRFSQALLK GDKSVRVMRS
       550        560        570        580        590        600
LLAAQQTFVD RLVHLMKAVQ RESGNRKKKN ERLQALLGDN EKMNLSDVEL IPLPLEPQVK
       610        620        630        640        650        660
IRGIIPETAT LFKSALMPAQ LFFKTEDGGK YPVIFKHGDD LRQDQLILQI ISLMDKLLRK
       670        680        690        700        710        720
ENLDLKLTPY KVLATSTKHG FMQFIQSVPV AEVLDTEGSI QNFFRKYAPS ENGPNGISAE
       730        740        750        760        770        780
VMDTYVKSCA GYCVITYILG VGDRHLDNLL LTKTGKLFHI DFGYILGRDP KPLPPPMKLN
       790        800        810        820        830        840
KEMVEGMGGT QSEQYQEFRK QCYTAFLHLR RYSNLILNLF SLMVDANIPD IALEPDKTVK
       850        860        870        880
KVQDKFRLDL SDEEAVHYMQ SLIDESVHAL FAAVVEQIHK FAQYWRK

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8NEB9-1-unknown	MGEAEK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8NEB9-516-unknown	MYLNVM...	516	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471229
Q8NEB9-516-unknown	MYLNVM...	516	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471443
Q8NEB9-516-unknown	MYLNVM...	516	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472464
Q8NEB9-654-unknown	MDKLLR...	654	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471957
Q8NEB9-654-unknown	MDKLLR...	654	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473061
Q8NEB9-777-unknown	MKLNKE...	777	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470524
Q8NEB9-823-unknown	MVDANI...	823	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471498

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RESGNR	565	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472464
...ISLMDK	655	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471443
...DKFRLD	848	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000469362
...QYWRK	887	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)