Q8NEZ5: F-box only protein 22

General Information

Protein names	- F-box only protein 22 - F-box protein FBX22p44
Gene names	FBXO22
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8NEZ5

5 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of F-box only protein 22 - Isoform 3 of F-box only protein 22

Sequence View

        10         20         30         40         50         60
MEPVGCCGEC RGSSVDPRST FVLSNLAEVV ERVLTFLPAK ALLRVACVCR LWRECVRRVL
        70         80         90        100        110        120
RTHRSVTWIS AGLAEAGHLE GHCLVRVVAE ELENVRILPH TVLYMADSET FISLEECRGH
       130        140        150        160        170        180
KRARKRTSME TALALEKLFP KQCQVLGIVT PGIVVTPMGS GSNRPQEIEI GESGFALLFP
       190        200        210        220        230        240
QIEGIKIQPF HFIKDPKNLT LERHQLTEVG LLDNPELRVV LVFGYNCCKV GASNYLQQVV
       250        260        270        280        290        300
STFSDMNIIL AGGQVDNLSS LTSEKNPLDI DASGVVGLSF SGHRIQSATV LLNEDVSDEK
       310        320        330        340        350        360
TAEAAMQRLK AANIPEHNTI GFMFACVGRG FQYYRAKGNV EADAFRKFFP SVPLFGFFGN
       370        380        390        400
GEIGCDRIVT GNFILRKCNE VKDDDLFHSY TTIMALIHLG SSK         10         20         30         40         50         60
MEPVGCCGEC RGSSVDPRST FVLSNLAEVV ERVLTFLPAK ALLRVACVCR LWRECVRRVL
        70         80         90        100        110        120
RTHRSVTWIS AGLAEAGHLE GHCLVRVVAE ELENVRILPH TVLYMADSET FISLEECRGH
       130        140        150        160        170        180
KRARKRTSME TALALEKLFP KQCQVLGIVT PGIVVTPMGS GSNRPQEIEI GESGFALLFP
       190        200        210        220        230        240
QIEGIKIQPF HFIKDPKNLT LERHQLTEVG LLDNPELRVV LVFGYNCCKV GASNYLQQVV
       250        260        270        280        290        300
STFSDMNIIL AGGQVDNLSS LTSEKNPLDI DASGVVGLSF SGHRIQSATV LLNEDVSDEK
       310        320        330        340        350        360
TAEAAMQRLK AANIPEHNTI GFMFACVGRG FQYYRAKGNV EADAFRKFFP SVPLFGFFGN
       370        380        390        400
GEIGCDRIVT GNFILRKCNE VKDDDLFHSY TTIMALIHLG SSK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8NEZ5-1-Acetylation	MEPVGC...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8NEZ5-1-Acetylation	MEPVGC...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q8NEZ5-1-Acetylation	MEPVGC...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q8NEZ5-1-Acetylation	MEPVGC...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q8NEZ5-1-Acetylation	MEPVGC...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt99252
Q8NEZ5-1-Acetylation	MEPVGC...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt99253
Q8NEZ5-1-unknown	MEPVGC...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74903
Q8NEZ5-1-unknown	MEPVGC...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74904
Q8NEZ5-7-unknown	CGECRG...	7		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457177
Q8NEZ5-7-unknown	CGECRG...	7		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194758
Q8NEZ5-7-unknown	CGECRG...	7		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194759
Q8NEZ5-105-unknown	MADSET...	105		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457569
Q8NEZ5-105-unknown	MADSET...	105		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000439270
Q8NEZ5-105-unknown	MADSET...	105		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197066
Q8NEZ5-304-unknown	AAMQRL...	304		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457297

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LLRVAC	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70521
...LLRVAC	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91361
...SLTSEK	264	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457569
...DEKTAE	302	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457177
...KCNEVK	381	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457297
...LGSSK	403	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)