TopFIND 4.0

Q8NFF5: FAD synthase

General Information

Protein names
- FAD synthase
- 2.7.7.2 {ECO:0000269|PubMed:16643857}
- FAD pyrophosphorylase
- FMN adenylyltransferase
- Flavin adenine dinucleotide synthase
- Molybdenum cofactor biosynthesis protein-like region
- FAD synthase region
Gene names FLAD1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NFF5

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGWDLGTRLF QRQEQRSRLS RIWLEKTRVF LEGSTRTPAL PHCLFWLLQV PSTQDPLFPG 
        70         80         90        100        110        120 
YGPQCPVDLA GPPCLRPLFG GLGGYWRALQ RGREGRTMTS RASELSPGRS VTAGIIIVGD 
       130        140        150        160        170        180 
EILKGHTQDT NTFFLCRTLR SLGVQVCRVS VVPDEVATIA AEVTSFSNRF THVLTAGGIG 
       190        200        210        220        230        240 
PTHDDVTFEA VAQAFGDELK PHPKLEAATK ALGGEGWEKL SLVPSSARLH YGTDPCTGQP 
       250        260        270        280        290        300 
FRFPLVSVRN VYLFPGIPEL LRRVLEGMKG LFQNPAVQFH SKELYVAADE ASIAPILAEA 
       310        320        330        340        350        360 
QAHFGRRLGL GSYPDWGSNY YQVKLTLDSE EEGPLEECLA YLTARLPQGS LVPYMPNAVE 
       370        380        390        400        410        420 
QASEAVYKLA ESGSSLGKKV AGALQTIETS LAQYSLTQLC VGFNGGKDCT ALLHLFHAAV 
       430        440        450        460        470        480 
QRKLPDVPNP LQILYIRSIS PFPELEQFLQ DTIKRYNLQM LEAEGSMKQA LGELQARHPQ 
       490        500        510        520        530        540 
LEAVLMGTRR TDPYSCSLCP FSPTDPGWPA FMRINPLLDW TYRDIWDFLR QLFVPYCILY 
       550        560        570        580    
DRGYTSLGSR ENTVRNPALK CLSPGGHPTY RPAYLLENEE EERNSRT

Isoforms

- Isoform 2 of FAD synthase - Isoform 3 of FAD synthase - Isoform 4 of FAD synthase - Isoform 5 of FAD synthase

Sequence View

        10         20         30         40         50         60 
MGWDLGTRLF QRQEQRSRLS RIWLEKTRVF LEGSTRTPAL PHCLFWLLQV PSTQDPLFPG 
        70         80         90        100        110        120 
YGPQCPVDLA GPPCLRPLFG GLGGYWRALQ RGREGRTMTS RASELSPGRS VTAGIIIVGD 
       130        140        150        160        170        180 
EILKGHTQDT NTFFLCRTLR SLGVQVCRVS VVPDEVATIA AEVTSFSNRF THVLTAGGIG 
       190        200        210        220        230        240 
PTHDDVTFEA VAQAFGDELK PHPKLEAATK ALGGEGWEKL SLVPSSARLH YGTDPCTGQP 
       250        260        270        280        290        300 
FRFPLVSVRN VYLFPGIPEL LRRVLEGMKG LFQNPAVQFH SKELYVAADE ASIAPILAEA 
       310        320        330        340        350        360 
QAHFGRRLGL GSYPDWGSNY YQVKLTLDSE EEGPLEECLA YLTARLPQGS LVPYMPNAVE 
       370        380        390        400        410        420 
QASEAVYKLA ESGSSLGKKV AGALQTIETS LAQYSLTQLC VGFNGGKDCT ALLHLFHAAV 
       430        440        450        460        470        480 
QRKLPDVPNP LQILYIRSIS PFPELEQFLQ DTIKRYNLQM LEAEGSMKQA LGELQARHPQ 
       490        500        510        520        530        540 
LEAVLMGTRR TDPYSCSLCP FSPTDPGWPA FMRINPLLDW TYRDIWDFLR QLFVPYCILY 
       550        560        570        580    
DRGYTSLGSR ENTVRNPALK CLSPGGHPTY RPAYLLENEE EERNSRT         10         20         30         40         50         60 
MGWDLGTRLF QRQEQRSRLS RIWLEKTRVF LEGSTRTPAL PHCLFWLLQV PSTQDPLFPG 
        70         80         90        100        110        120 
YGPQCPVDLA GPPCLRPLFG GLGGYWRALQ RGREGRTMTS RASELSPGRS VTAGIIIVGD 
       130        140        150        160        170        180 
EILKGHTQDT NTFFLCRTLR SLGVQVCRVS VVPDEVATIA AEVTSFSNRF THVLTAGGIG 
       190        200        210        220        230        240 
PTHDDVTFEA VAQAFGDELK PHPKLEAATK ALGGEGWEKL SLVPSSARLH YGTDPCTGQP 
       250        260        270        280        290        300 
FRFPLVSVRN VYLFPGIPEL LRRVLEGMKG LFQNPAVQFH SKELYVAADE ASIAPILAEA 
       310        320        330        340        350        360 
QAHFGRRLGL GSYPDWGSNY YQVKLTLDSE EEGPLEECLA YLTARLPQGS LVPYMPNAVE 
       370        380        390        400        410        420 
QASEAVYKLA ESGSSLGKKV AGALQTIETS LAQYSLTQLC VGFNGGKDCT ALLHLFHAAV 
       430        440        450        460        470        480 
QRKLPDVPNP LQILYIRSIS PFPELEQFLQ DTIKRYNLQM LEAEGSMKQA LGELQARHPQ 
       490        500        510        520        530        540 
LEAVLMGTRR TDPYSCSLCP FSPTDPGWPA FMRINPLLDW TYRDIWDFLR QLFVPYCILY 
       550        560        570        580    
DRGYTSLGSR ENTVRNPALK CLSPGGHPTY RPAYLLENEE EERNSRT         10         20         30         40         50         60 
MGWDLGTRLF QRQEQRSRLS RIWLEKTRVF LEGSTRTPAL PHCLFWLLQV PSTQDPLFPG 
        70         80         90        100        110        120 
YGPQCPVDLA GPPCLRPLFG GLGGYWRALQ RGREGRTMTS RASELSPGRS VTAGIIIVGD 
       130        140        150        160        170        180 
EILKGHTQDT NTFFLCRTLR SLGVQVCRVS VVPDEVATIA AEVTSFSNRF THVLTAGGIG 
       190        200        210        220        230        240 
PTHDDVTFEA VAQAFGDELK PHPKLEAATK ALGGEGWEKL SLVPSSARLH YGTDPCTGQP 
       250        260        270        280        290        300 
FRFPLVSVRN VYLFPGIPEL LRRVLEGMKG LFQNPAVQFH SKELYVAADE ASIAPILAEA 
       310        320        330        340        350        360 
QAHFGRRLGL GSYPDWGSNY YQVKLTLDSE EEGPLEECLA YLTARLPQGS LVPYMPNAVE 
       370        380        390        400        410        420 
QASEAVYKLA ESGSSLGKKV AGALQTIETS LAQYSLTQLC VGFNGGKDCT ALLHLFHAAV 
       430        440        450        460        470        480 
QRKLPDVPNP LQILYIRSIS PFPELEQFLQ DTIKRYNLQM LEAEGSMKQA LGELQARHPQ 
       490        500        510        520        530        540 
LEAVLMGTRR TDPYSCSLCP FSPTDPGWPA FMRINPLLDW TYRDIWDFLR QLFVPYCILY 
       550        560        570        580    
DRGYTSLGSR ENTVRNPALK CLSPGGHPTY RPAYLLENEE EERNSRT         10         20         30         40         50         60 
MGWDLGTRLF QRQEQRSRLS RIWLEKTRVF LEGSTRTPAL PHCLFWLLQV PSTQDPLFPG 
        70         80         90        100        110        120 
YGPQCPVDLA GPPCLRPLFG GLGGYWRALQ RGREGRTMTS RASELSPGRS VTAGIIIVGD 
       130        140        150        160        170        180 
EILKGHTQDT NTFFLCRTLR SLGVQVCRVS VVPDEVATIA AEVTSFSNRF THVLTAGGIG 
       190        200        210        220        230        240 
PTHDDVTFEA VAQAFGDELK PHPKLEAATK ALGGEGWEKL SLVPSSARLH YGTDPCTGQP 
       250        260        270        280        290        300 
FRFPLVSVRN VYLFPGIPEL LRRVLEGMKG LFQNPAVQFH SKELYVAADE ASIAPILAEA 
       310        320        330        340        350        360 
QAHFGRRLGL GSYPDWGSNY YQVKLTLDSE EEGPLEECLA YLTARLPQGS LVPYMPNAVE 
       370        380        390        400        410        420 
QASEAVYKLA ESGSSLGKKV AGALQTIETS LAQYSLTQLC VGFNGGKDCT ALLHLFHAAV 
       430        440        450        460        470        480 
QRKLPDVPNP LQILYIRSIS PFPELEQFLQ DTIKRYNLQM LEAEGSMKQA LGELQARHPQ 
       490        500        510        520        530        540 
LEAVLMGTRR TDPYSCSLCP FSPTDPGWPA FMRINPLLDW TYRDIWDFLR QLFVPYCILY 
       550        560        570        580    
DRGYTSLGSR ENTVRNPALK CLSPGGHPTY RPAYLLENEE EERNSRT



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NFF5-18-unknown RLSRIW... 18 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8NFF5-98-unknown MTSRAS... 98 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74720
    Q8NFF5-98-unknown MTSRAS... 98 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74721

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)