TopFIND 4.0

Q8NFZ5: TNFAIP3-interacting protein 2

General Information

Protein names
- TNFAIP3-interacting protein 2
- A20-binding inhibitor of NF-kappa-B activation 2
- ABIN-2
- Fetal liver LKB1-interacting protein
Gene names TNIP2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NFZ5

4

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRDPGSGGW EEAPRAAAAL CTLYHEAGQR LRRLQDQLAA RDALIARLRA RLAALEGDAA 
        70         80         90        100        110        120 
PSLVDALLEQ VARFREQLRR QEGGAAEAQM RQEIERLTER LEEKEREMQQ LLSQPQHERE 
       130        140        150        160        170        180 
KEVVLLRRSM AEGERARAAS DVLCRSLANE THQLRRTLTA TAHMCQHLAK CLDERQHAQR 
       190        200        210        220        230        240 
NVGERSPDQS EHTDGHTSVQ SVIEKLQEEN RLLKQKVTHV EDLNAKWQRY NASRDEYVRG 
       250        260        270        280        290        300 
LHAQLRGLQI PHEPELMRKE ISRLNRQLEE KINDCAEVKQ ELAASRTARD AALERVQMLE 
       310        320        330        340        350        360 
QQILAYKDDF MSERADRERA QSRIQELEEK VASLLHQVSW RQDSREPDAG RIHAGSKTAK 
       370        380        390        400        410        420 
YLAADALELM VPGGWRPGTG SQQPEPPAEG GHPGAAQRGQ GDLQCPHCLQ CFSDEQGEEL 
   
LRHVAECCQ

Isoforms

- Isoform 2 of TNFAIP3-interacting protein 2

Sequence View

        10         20         30         40         50         60 
MSRDPGSGGW EEAPRAAAAL CTLYHEAGQR LRRLQDQLAA RDALIARLRA RLAALEGDAA 
        70         80         90        100        110        120 
PSLVDALLEQ VARFREQLRR QEGGAAEAQM RQEIERLTER LEEKEREMQQ LLSQPQHERE 
       130        140        150        160        170        180 
KEVVLLRRSM AEGERARAAS DVLCRSLANE THQLRRTLTA TAHMCQHLAK CLDERQHAQR 
       190        200        210        220        230        240 
NVGERSPDQS EHTDGHTSVQ SVIEKLQEEN RLLKQKVTHV EDLNAKWQRY NASRDEYVRG 
       250        260        270        280        290        300 
LHAQLRGLQI PHEPELMRKE ISRLNRQLEE KINDCAEVKQ ELAASRTARD AALERVQMLE 
       310        320        330        340        350        360 
QQILAYKDDF MSERADRERA QSRIQELEEK VASLLHQVSW RQDSREPDAG RIHAGSKTAK 
       370        380        390        400        410        420 
YLAADALELM VPGGWRPGTG SQQPEPPAEG GHPGAAQRGQ GDLQCPHCLQ CFSDEQGEEL 
   
LRHVAECCQ



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NFZ5-1-unknown MSRDPG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8NFZ5-108-unknown MQQLLS... 108 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92624
    Q8NFZ5-195-unknown GHTSVQ... 195 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt165786
    Q8NFZ5-195- GHTSVQ... 195 Subtiligase Based Positive Selection Wells apoptotic_DB_Doxo 23264352

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AECCQ 429 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...AECCQ 429 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt88242

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)