TopFIND 4.0

Q8NHS4: Clathrin heavy chain linker domain-containing protein 1

General Information

Protein names
- Clathrin heavy chain linker domain-containing protein 1
Gene names CLHC1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NHS4

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSVHQIRKHA VLPPIICRSD KEFLESVQRY IITETERLGC SEEGPADEYY IIYRNVFDKV 
        70         80         90        100        110        120 
IEHITAYKSI LTSIKKEYDA FIETIKKDRR TTFCLHGKLK GLAAEPTALV YYRKRTIQLE 
       130        140        150        160        170        180 
AKMRIIESNS SKIQSQIDHI KQCRAEYDTK EVKYCTFSKD PSKPIPGMTL QESMNLDALT 
       190        200        210        220        230        240 
KYMKHLEDKY AEIKQAMLIK YVPAQRKADL DEEMIVLLKR RDVAENLNKK LQFCHQRLQI 
       250        260        270        280        290        300 
ISQALSSWVK SDMSSPFQDF VEQIQKTKYL QGDQGIVEEL MEDDPRRAKE AEIMLHYIER 
       310        320        330        340        350        360 
FNELISLGEY EKAACYAANS PRRILRNIGT MNTFKAVGKI RGKPLPLLLF FEALFITSHA 
       370        380        390        400        410        420 
FPCPVDAALT LEGIKCGLSE KRLDLVTNWV TQERLTFSEE AGDVICDYGE QDTYNKAKCL 
       430        440        450        460        470        480 
ALAQIVYSEC GLHKKAILCL CKQGQTHRVM EYIQQLKDFT TDDLLQLLMS CPQVELIQCL 
       490        500        510        520        530        540 
TKELNEKQPS LSFGLAILHL FSADMKKVGI KLLQEINKGG IDAVESLMIN DSFCSIEKWQ 
       550        560        570        580    
EVANICSQNG FDKLSNDITS ILRSQAAVTE ISEEDDAVNL MEHVFW

Isoforms

- Isoform 2 of Clathrin heavy chain linker domain-containing protein 1

Sequence View

        10         20         30         40         50         60 
MSVHQIRKHA VLPPIICRSD KEFLESVQRY IITETERLGC SEEGPADEYY IIYRNVFDKV 
        70         80         90        100        110        120 
IEHITAYKSI LTSIKKEYDA FIETIKKDRR TTFCLHGKLK GLAAEPTALV YYRKRTIQLE 
       130        140        150        160        170        180 
AKMRIIESNS SKIQSQIDHI KQCRAEYDTK EVKYCTFSKD PSKPIPGMTL QESMNLDALT 
       190        200        210        220        230        240 
KYMKHLEDKY AEIKQAMLIK YVPAQRKADL DEEMIVLLKR RDVAENLNKK LQFCHQRLQI 
       250        260        270        280        290        300 
ISQALSSWVK SDMSSPFQDF VEQIQKTKYL QGDQGIVEEL MEDDPRRAKE AEIMLHYIER 
       310        320        330        340        350        360 
FNELISLGEY EKAACYAANS PRRILRNIGT MNTFKAVGKI RGKPLPLLLF FEALFITSHA 
       370        380        390        400        410        420 
FPCPVDAALT LEGIKCGLSE KRLDLVTNWV TQERLTFSEE AGDVICDYGE QDTYNKAKCL 
       430        440        450        460        470        480 
ALAQIVYSEC GLHKKAILCL CKQGQTHRVM EYIQQLKDFT TDDLLQLLMS CPQVELIQCL 
       490        500        510        520        530        540 
TKELNEKQPS LSFGLAILHL FSADMKKVGI KLLQEINKGG IDAVESLMIN DSFCSIEKWQ 
       550        560        570        580    
EVANICSQNG FDKLSNDITS ILRSQAAVTE ISEEDDAVNL MEHVFW



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NHS4-1-unknown MSVHQI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8NHS4-123-unknown MRIIES... 123 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70959

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EHVFW 586 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EHVFW 586 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt66577

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)