TopFIND 4.0

Q8NHV5: Modulator of smoothened protein {ECO:0000312|HGNC:HGNC:27087}

General Information

Protein names
- Modulator of smoothened protein {ECO:0000312|HGNC:HGNC:27087}
- Attenuator of hedgehog {ECO:0000250|UniProtKB:Q8C784}
Gene names C16orf52
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8NHV5

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDKLTIISGC LFLAADIFAI ASIANPDWIN TGESAGALTV GLVRQCQTIH GRDRTCIPPR 
        70         80         90        100        110        120 
LPPEWVTTLF FIIMGIISLT VTCGLLVASH WRREATKYAR WIAFTGMILF CMAALIFPIG 
       130        140        150        160    
FYINEVGGQP YKLPNNTVVG SSYVLFVLSI FFTIVGLLFA GKVCLPG

Isoforms

- Isoform 2 of Uncharacterized protein C16orf52 - Isoform 2 of Modulator of smoothened protein

Sequence View

        10         20         30         40         50         60 
MDKLTIISGC LFLAADIFAI ASIANPDWIN TGESAGALTV GLVRQCQTIH GRDRTCIPPR 
        70         80         90        100        110        120 
LPPEWVTTLF FIIMGIISLT VTCGLLVASH WRREATKYAR WIAFTGMILF CMAALIFPIG 
       130        140        150        160    
FYINEVGGQP YKLPNNTVVG SSYVLFVLSI FFTIVGLLFA GKVCLPG         10         20         30         40         50         60 
MDKLTIISGC LFLAADIFAI ASIANPDWIN TGESAGALTV GLVRQCQTIH GRDRTCIPPR 
        70         80         90        100        110        120 
LPPEWVTTLF FIIMGIISLT VTCGLLVASH WRREATKYAR WIAFTGMILF CMAALIFPIG 
       130        140        150        160    
FYINEVGGQP YKLPNNTVVG SSYVLFVLSI FFTIVGLLFA GKVCLPG



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8NHV5-1-unknown MDKLTI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8NHV5-1-unknown MDKLTI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71478

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VCLPG 167 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)