Q8R0W0: Epiplakin {ECO:0000303|PubMed:12791695}
Protein names | - Epiplakin {ECO:0000303|PubMed:12791695} |
---|---|
Gene names | Eppk1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q8R0W0 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MNGQAPPHDV VVANGTEKFI VPKIKKNQLG ASTPSRPQAE AALPTTARSI AGVYVEASGQ
70 80 90 100 110 120
TQSIYAAIKQ GLLPTGLGLT LLEAQAATGG LVDLAQGQLL PVSEALRRGL VGLELKEKLL
130 140 150 160 170 180
AAERAVTGYP DPYGGEKLSL FQAIKKEVVD RTLGWRLLEA QLATGGLVDP TQGVQVAPEL
190 200 210 220 230 240
ACQQGLLDKE TWLSLVESEP SMGTPGFSDP NTLEQLPYSV LLGRCVQDPS SGLPLLPLKT
250 260 270 280 290 300
TFHTLAGAAS ASMLLEAGVL NEEMVRDLQE GMLVVSDVGT RPEVRRYLEG TGGLAGVVLL
310 320 330 340 350 360
PGGHKKSFFQ ATVEHLVSKG IALQLLEAQA ATRTLVHPTT GQRLWVEEAV KAGLVGPELH
370 380 390 400 410 420
EQLLVAEQAV TGYYDPFSSS RIPVFQAMKK GLVDQPLALR LLDAQLATGG LICPARRFRL
430 440 450 460 470 480
PLEAALRFGC LDEETRQRLS QAMGFSDPTT HDRLGYEQLL ALSVTDPETG LAFLPLPGMS
490 500 510 520 530 540
HANEPQGPTF IDHCTRQALS KATTSISVGR YQGRPVSLWE LLFSESVPVK KRAMLAQRHQ
550 560 570 580 590 600
EGALSVEELA AELKNIVEQA AATAKVTFAG LRDTVTPGEL LKAEIINQDL FEQLERGQTS
610 620 630 640 650 660
AQDVGSLDSV QRYLQGTGSI AGLLLPDSQE RLSIYEARSK GLLRPGTALI LLEAQAATGF
670 680 690 700 710 720
IIDPKENKRY SVEEALRAGV IGPDVYAKLL SAEHAVTGYT DPYSGEQISL FQAMQRDLIV
730 740 750 760 770 780
RDHGIRLLEA QIATGGVIDP VHSHRVPVDV AYQRGYFDQI LNSILLDPSD DTKGFFDPNT
790 800 810 820 830 840
HENLTYLQLL ERCVHDSETG LHLLPLSSTR PQLVDSSTRQ AFQKLLLSVK YGRFRGQRVS
850 860 870 880 890 900
AWELVNSEYF TEDRRRQLLQ RYRQRKITLE QVTQLLEKEM RRWTDITLPA LQGQVTAYQL
910 920 930 940 950 960
LEAHIINQEL LDQVLTGTIS PDALLQVGDV HRYLRGSGTV GGVLLKPSNQ RISLYQAMKQ
970 980 990 1000 1010 1020
KLLPPSTALA LLEAQAATGT ITDPCSMETL SVDEAVCRGV VGAEVYGKLK RAEHSITGYR
1030 1040 1050 1060 1070 1080
DPFSGKKVSL FRAMKKGLVP VEQATRLLEA QVSTGGVVDP TTHLHLPMPV AVQRGCIDRE
1090 1100 1110 1120 1130 1140
MEAALSRSPE TFPTPDGRGH TSYAQLLEHC LQDKASGLHL LPLTEDAPNV PTDTQIQETL
1150 1160 1170 1180 1190 1200
QASAGTEDGL SLWDLLTSCH FTEEQRRGYL EDVKVGKISV PQLQNTVRSW VHSAKLLARA
1210 1220 1230 1240 1250 1260
RITVPGPRGE VPATWLRDAG IITQETLEAL AQGMQSPDEV AKQPTVKVCL WGTGCVAGVL
1270 1280 1290 1300 1310 1320
LQPSGTKLSI AQAVRDGLLP TGLGQQLLEA QVASGFLVNP LTNQRLSVEG AVKAGLVGME
1330 1340 1350 1360 1370 1380
QSEHLRQVEK AVTGYSDPFS GGSLSLWQAM EKGLVTQSEA FPLLQVQLAT GGVVDPVHGV
1390 1400 1410 1420 1430 1440
HLPQEVAYKL GLLDEQTSRV LTATGKENKL FFDPNSREKV TYQQLRELCV LDADTGLWLL
1450 1460 1470 1480 1490 1500
PLPQGTVLEV DDHTAVALRA MKVPINMGRF QGHSVSLWDL LHSEYVGAEK RRELVALCCS
1510 1520 1530 1540 1550 1560
GRAAALRQVI GMLTTLVEAA EKQPSQATFK GLRKQVSAGD LFRSQLITKQ TLDELNQGKR
1570 1580 1590 1600 1610 1620
TVQEVTEMDS VRRSLEGGNF IAGVLIQDTK EKMSIPEALR RHILRPGTAL VLLEAQAATG
1630 1640 1650 1660 1670 1680
FIIDPVENRK LTVEQAFQAG MFGKETYMKL LSAERAVTGY TDPYTGEQIS LFQAMQRDLI
1690 1700 1710 1720 1730 1740
VRDHGIRLLE AQIATGGIID PVHSHRVPVD VAYQRGYFNE EMNRILSDPS DDTKGFFDPN
1750 1760 1770 1780 1790 1800
THENLTYLQL LERCVEDPET GLYMLEIVKK GETYTYIDEA TRQALTSRTV KMYVGKFAGQ
1810 1820 1830 1840 1850 1860
TVSVWDLLSS QYFTEGRRRK LLREYRAQNI GLENLLEVIT STVEETEKQS QIFKVPGIHG
1870 1880 1890 1900 1910 1920
DVTAAELFNS GILNKKTLDA LRSGDRGFQD LRWLEDVRVY LEGSNYIAGV IAPLTQKVMS
1930 1940 1950 1960 1970 1980
FYEASREELI PAGFAAQMLE AQAATGYLMD PCTNQRLCVD EAIAAGLVGE DLRERLVNAE
1990 2000 2010 2020 2030 2040
MAAKGYKDPA TGETIPLYQA MERKLVGREE ALRLLEVQVA TGGVIDPRHH HRVPLDTACQ
2050 2060 2070 2080 2090 2100
RGCMCDDSLV LIADQKHMRK RFVDPNTQEK VTYQELQDRC QREEKSGWAL FPVVKDKKDI
2110 2120 2130 2140 2150 2160
EYVDEATKRA LEAEQVEVTV GRYRGQRRSV WELLNSEYVS EEKKMELVRL YKEDTTRALQ
2170 2180 2190 2200 2210 2220
KVVELILQMI ADKERRSRQL WFRGLRTQVT AEELLRSEVI TKQTLEDLEE GRTTVDQIER
2230 2240 2250 2260 2270 2280
KEDVKRYLKG TSCIAGVLVP VQGEPGRQEK MSIYQAMWKG VLRPGTALVL LEAQAATGFI
2290 2300 2310 2320 2330 2340
IDPVNNRRLS VEEAVAAGVV GGEIQEKLLS AERAVTGYTD PYTGDQISLF QAMQRDLIVR
2350 2360 2370 2380 2390 2400
DHGIRLLEAQ IATGGVIDPV HSHRVPVDVA YQRGYFDEDM NSILADPGDD TKGFFDPNTH
2410 2420 2430 2440 2450 2460
ENLTYLQLLR RCVRDPETGF YMLQLAGKGS SVHHLSEELR RALREARVTP GTGDFQGQSI
2470 2480 2490 2500 2510 2520
SVWELLFYRE VPESLRQDLL RCYQAGGLTV HDVTTTLTSL LARAKDGSPR GDPQGALGKA
2530 2540 2550 2560 2570 2580
TMEVKRGHLR GHEVPVWDIL TSNYVSRDTR KELLAQFSSG SLTLPMLKRR LTTIIEEAEE
2590 2600 2610 2620 2630 2640
TQESKPKPRD ASLKQQDTGA RGSGTSPDEG DAQDSSESAR QQQEQTLRAT TMQVHRGQFR
2650 2660 2670 2680 2690 2700
DQQVSVWKVL FSSYLSETRR EELLAQHLAG KLGVMELVSL LTQIIEETEE RLSKVSFPGL
2710 2720 2730 2740 2750 2760
RRQVSASELC TSGILDRDTM RELAQGTKTI HEVTEMDSVK RYLGGSSCIA GVLVPVQGEP
2770 2780 2790 2800 2810 2820
GRQEKMSIYQ AMWKGVLRPG TALVLLEAQA ATGFIIDPVN NRRLSVEEAV AAGVVGGEIQ
2830 2840 2850 2860 2870 2880
EKLLSAERAV TGYTDPYTGD QISLFQAMQR DLIVRDHGIR LLEAQIATGG VIDPVHSHRV
2890 2900 2910 2920 2930 2940
PVDVAYQRGY FDEDMNSILA DPGDDTKGFF DPNTHENLTY LQLLRRCVRD PETGFYMLQL
2950 2960 2970 2980 2990 3000
AGKGSSVHHL SEELRRALRE ARVTPGTGDF QGQSISVWEL LFYREVPESL RQDLLRRYQA
3010 3020 3030 3040 3050 3060
GGLTVHDVTT TLTSLLARAK DGSPRXDPQG ALGKATMEVK RGHLRGHXVP VWDILTSNYV
3070 3080 3090 3100 3110 3120
SRDTRKELLA QFSSGSLTLP MLKRRLTTII EEAEETQESK PKPRDASLKQ QDTGARGSGT
3130 3140 3150 3160 3170 3180
SPDEGDAQDS SESARQQQEQ TLRATTMQVH RGQFRDQQVS VWKVLFSSYL SETRREELLA
3190 3200 3210 3220 3230 3240
QHLAGKLGVM ELVSLLTQII EETEERLSKV SFPGLRRQVS ASELCTSGIL DRDTMRELAQ
3250 3260 3270 3280 3290 3300
GTKTIHEVTE MDSVKRYLGG SSCIAGVLVP VQGEPGRQEK MSIYQAMWKG VLRPGTALVL
3310 3320 3330 3340 3350 3360
LEAQAATGFI IDPVNNRRLS VEEAVAAGVV GGEIQEKLLS AERAVTGYTD PYTGDQISLF
3370 3380 3390 3400 3410 3420
QAMQRDLIVR DHGIRLLEAQ IATGGVIDPV HSHRVPVDVA YQRGYFDEDM NSILADPGDD
3430 3440 3450 3460 3470 3480
TKGFFDPNTH ENLTYLQLLR RCVRDPETGF YMLQLAGKGS SVHHLSEELR RALREARVTP
3490 3500 3510 3520 3530 3540
GTGDFQGQSI SVWELLFYRE VPESLRQDLL RRYQAGGLTV HDVTTTLTSL LARAKDGSPR
3550 3560 3570 3580 3590 3600
XDPQGALGKA TMEVKRGHLR GHXVPVWDIL TSNYVSRDTR KELLAQFSSG SLTLPMLKRR
3610 3620 3630 3640 3650 3660
LTTIIEEAEE TQESKPKPRD ASLKQQDTGA RGSGTSPDEG DAQDSSESAR QQQEQTLRAT
3670 3680 3690 3700 3710 3720
TMQVHRGQFR DQQVSVWKVL FSSYLSETRR EELLAQHLAG KLGVMELVSL LTQIIEETEE
3730 3740 3750 3760 3770 3780
RLSKVSFPGL RRQVSASELC TSGILDRDTM RELAQGTKTI HEVTEMDSVK RYLGGSSCIA
3790 3800 3810 3820 3830 3840
GVLVPVQGEP GRQEKMSIYQ AMWKGVLRPG TALVLLEAQA ATGFIIDPVN NRRLSVEEAV
3850 3860 3870 3880 3890 3900
AAGVVGGEIQ EKLLSAERAV TGYTDPYTGD QISLFQAMQR DLIVRDHGIR LLEAQIATGG
3910 3920 3930 3940 3950 3960
VIDPVHSHRV PVDVAYQRGY FDEDMNSILA DPGDDTKGFF DPNTHENLTY LQLLRRCVRD
3970 3980 3990 4000 4010 4020
PETGFYMLQL AGKGSSVHHL SEELRRALRE ARVTPGTGDF QGQSISVWEL LFYREVPESL
4030 4040 4050 4060 4070 4080
RQDLLRRYQA GGLTVHDVTT TLTSLLARAK DGSPRXDPQG ALGKATMEVK RGHLRGHXVP
4090 4100 4110 4120 4130 4140
VWDILTSNYV SRDTRKELLA QFSSGSLTLP MLKRRLTTII EEAEETQESK PKPRDASLKQ
4150 4160 4170 4180 4190 4200
QDTGARGSGT SPDEGDAQDS SESARQQQEQ TLRATTMQVH RGQFRDQQVS VWKVLFSSYL
4210 4220 4230 4240 4250 4260
SETRREELLA QHLAGKLGVM ELVSLLTQII EETEERLSKV SFPGLRRQVS ASELCTSGIL
4270 4280 4290 4300 4310 4320
DRDTMRELAQ GTKTIHEVTE MDSVKRYLGG SSCIAGVLVP VQGEPGRQEK MSIYQAMWKG
4330 4340 4350 4360 4370 4380
VLRPGTALVL LEAQAATGFI IDPVNNRRLS VEEAVAAGVV GGEIQEKLLS AERAVTGYTD
4390 4400 4410 4420 4430 4440
PYTGDQISLF QAMQRDLIVR DHGIRLLEAQ IATGGVIDPV HSHRVPVDVA YQRGYFDEDM
4450 4460 4470 4480 4490 4500
NSILADPGDD TKGFFDPNTH ENLTYLQLLR RCVRDPETGF YMLQLAGKGS SVHHLSEELR
4510 4520 4530 4540 4550 4560
RALREARVTP GTGDFQGQSI SVWELLFYRE VPESLRQDLL RRYQAGGLTV HDVTTTLTSL
4570 4580 4590 4600 4610 4620
LARAKDGSPR XDPQGALGKA TMEVKRGHLR GHXVPVWDIL TSNYVSRDTR KELLAQFSSG
4630 4640 4650 4660 4670 4680
SLTLPMLKRR LTTIIEEAEE TQESKPKPRD ASLKQQDTGA RGSGTSPDEG DAQDSSESAR
4690 4700 4710 4720 4730 4740
QQQEQTLRAT TMQVHRGQFR DQQVSVWKVL FSSYLSETRR EELLAQHLAG KLGVMELVSL
4750 4760 4770 4780 4790 4800
LTQIIEETEE RLSKVSFPGL RRQVSASELC TSGILDRDTM RELAQGTKTI HEVTEMDSVK
4810 4820 4830 4840 4850 4860
RYLGGSSCIA GVLVPVQGEP GRQEKMSIYQ AMWKGVLRPG TALVLLEAQA ATGFIIDPVN
4870 4880 4890 4900 4910 4920
NRRLSVEEAV AAGVVGGEIQ EKLLSAERAV TGYTDPYTGD QISLFQAMQR DLIVRDHGIR
4930 4940 4950 4960 4970 4980
LLEAQIATGG VIDPVHSHRV PVDVAYQRGY FDEDMNSILA DPGDDTKGFF DPNTHENLTY
4990 5000 5010 5020 5030 5040
LQLLRRCVRD PETGFYMLQL AGKGSSVHHL SEELRRALRE ARVTPGTGDF QGQSISVWEL
5050 5060 5070 5080 5090 5100
LFYREVPESL RQDLLRRYQA GGLTVHDVTT TLTSLLARAK DGSPRXDPQG ALGKATMEVK
5110 5120 5130 5140 5150 5160
RGHLRGHXVP VWDILTSNYV SRDTRKELLA QFSSGSLTLP MLKRRLTTII EEAEETQESK
5170 5180 5190 5200 5210 5220
PKPRDASLKQ QDTGARGSGT SPDEGDAQDS SESARQQQEQ TLRATTMQVH RGQFRDQQVS
5230 5240 5250 5260 5270 5280
VWKVLFSSYL SETRREELLA QHLAGKLGVM ELVSLLTQII EETEERLSKV SFPGLRRQVS
5290 5300 5310 5320 5330 5340
ASELCTSGIL DRDTMRELAQ GTKTIHEVTE MDSVKRYLGG SSCIAGVLVP VQGEPGRQEK
5350 5360 5370 5380 5390 5400
MSIYQAMWKG VLRPGTALVL LEAQAATGFI IDPVNNRRLS VEEAVAAGVV GGEIQEKLLS
5410 5420 5430 5440 5450 5460
AERAVTGYTD PYTGDQISLF QAMQRDLIVR DHGIRLLEAQ IATGGVIDPV HSHRVPVDVA
5470 5480 5490 5500 5510 5520
YQRGYFDEDM NSILADPGDD TKGFFDPNTH ENLTYLQLLR RCVRDPETGF YMLQLAGKGS
5530 5540 5550 5560 5570 5580
SVHHLSEELR RALREARVTP GTGDFQGQSI SVWELLFYRE VPESLRQDLL RRYQAGGLTV
5590 5600 5610 5620 5630 5640
HDVTTTLTSL LARAKDGSPR XDPQGALGKA TMEVKRGHLR GHXVPVWDIL TSNYVSRDTR
5650 5660 5670 5680 5690 5700
KELLAQFSSG SLTLPMLKRR LTTIIEEAEE TQESKPKPRD ASLKQQDTGA RGSGTSPDEG
5710 5720 5730 5740 5750 5760
DAQDSSESAR QQQEQTLRAT TMQVHRGQFR DQQVSVWKVL FSSYLSETRR EELLAQHLAG
5770 5780 5790 5800 5810 5820
KLGVMELVSL LTQIIEETEE RLSKVSFPGL RRQVSASELC TSGILDRDTM RELAQGTKTI
5830 5840 5850 5860 5870 5880
HEVTEMDSVK RYLGGSSCIA GVLVPVQGEP GRQEKMSIYQ AMWKGVLRPG TALVLLEAQA
5890 5900 5910 5920 5930 5940
ATGFIIDPVN NRRLSVEEAV AAGVVGGEIQ EKLLSAERAV TGYTDPYTGD QISLFQAMQR
5950 5960 5970 5980 5990 6000
DLIVRDHGIR LLEAQIATGG VIDPVHSHRV PVDVAYQRGY FDEDMNSILA DPGDDTKGFF
6010 6020 6030 6040 6050 6060
DPNTHENLTY LQLLRRCVRD PETGFYMLQL AGKGSSVHHL SEELRRALRE ARVTPGTGDF
6070 6080 6090 6100 6110 6120
QGQSISVWEL LFYREVPESL RQDLLRRYQA GGLTVHDVTT TLTSLLARAK DGSPREDPQG
6130 6140 6150 6160 6170 6180
ALGKATMEVK RGHLRGHVVP VWDILTSNYV SRDTRKELLA QFSSGSLTLP MLKRRLTTII
6190 6200 6210 6220 6230 6240
EEAEETQESK PKPRDASLKQ QDTGARGSGT SPDEGDAQDS SESARQQQEQ TLRATTMQVH
6250 6260 6270 6280 6290 6300
RGQFRDQQVS VWKVLFSSYL SETRREELLA QHLAGKLGVM ELVSLLTQII EETEERLSKV
6310 6320 6330 6340 6350 6360
SFPGLRRQVS ASELCTSGIL DRDTMRELAQ GTKTIHEVTE MDSVKRYLGG SSCIAGVLVP
6370 6380 6390 6400 6410 6420
VQGEPGRQEK MSIYQAMWKG VLRPGTALVL LEAQAATGFI IDPVNNRRLS VEEAVAAGVV
6430 6440 6450 6460 6470 6480
GGEIQEKLLS AERAVTGYTD PYTGDQISLF QAMQRDLIVK NHGIRLLEAQ IATGGVIDPV
6490 6500 6510 6520 6530 6540
HSHRVPVDVA YQRGYFDQEM NSILADPGDD TKGFFDPNTH ENLTYLQLLQ RATIDPETGL
LFLSLSKG
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8R0W0-1-unknown | MNGQAP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SLSKG | 6548 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|