TopFIND 4.0

Q8R116: Palmitoleoyl-protein carboxylesterase NOTUM {ECO:0000250|UniProtKB:Q6P988}

General Information

Protein names
- Palmitoleoyl-protein carboxylesterase NOTUM {ECO:0000250|UniProtKB:Q6P988}
- 3.1.1.98 {ECO:0000250|UniProtKB:Q6P988}
Gene names Notum
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8R116

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGGEVRVLLL LGLLHWVGGS EGRKTWRRRG QQPPQPPPPP PLPQRAEVEP GAGQPVESFP 
        70         80         90        100        110        120 
LDFTAVEGNM DSFMAQVKSL AQSLYPCSAQ QLNEDLRLHL LLNTSVTCND GSPAGYYLKE 
       130        140        150        160        170        180 
SKGSRRWLLF LEGGWYCFNR ENCDSRYSTM RRLMSSKDWP HTRTGTGILS SQPEENPHWW 
       190        200        210        220        230        240 
NANMVFIPYC SSDVWSGASP KSDKNEYAFM GSLIIQEVVR ELLGKGLSGA KVLLLAGSSA 
       250        260        270        280        290        300 
GGTGVLLNVD RVAELLEELG YPSIQVRGLA DSGWFLDNKQ YRRSDCIDTI NCAPTDAIRR 
       310        320        330        340        350        360 
GIRYWSGMVP ERCQRQFKEG EEWNCFFGYK VYPTLRCPVF VVQWLFDEAQ LTVDNVHLTG 
       370        380        390        400        410        420 
QPVQEGQWLY IQNLGRELRG TLKDVQASFA PACLSHEIII RSYWTDVQVK GTSLPRALHC 
       430        440        450        460        470        480 
WDRSFHDSHK ASKTPMKGCP FHLVDSCPWP HCNPSCPTIR DQFTGQEMNV AQFLMHMGFD 
       490        500    
VQTVAQQQGM EPSKLLGMLS NGN

Isoforms

- Isoform 2 of Protein notum homolog - Isoform 2 of Palmitoleoyl-protein carboxylesterase NOTUM

Sequence View

        10         20         30         40         50         60 
MGGEVRVLLL LGLLHWVGGS EGRKTWRRRG QQPPQPPPPP PLPQRAEVEP GAGQPVESFP 
        70         80         90        100        110        120 
LDFTAVEGNM DSFMAQVKSL AQSLYPCSAQ QLNEDLRLHL LLNTSVTCND GSPAGYYLKE 
       130        140        150        160        170        180 
SKGSRRWLLF LEGGWYCFNR ENCDSRYSTM RRLMSSKDWP HTRTGTGILS SQPEENPHWW 
       190        200        210        220        230        240 
NANMVFIPYC SSDVWSGASP KSDKNEYAFM GSLIIQEVVR ELLGKGLSGA KVLLLAGSSA 
       250        260        270        280        290        300 
GGTGVLLNVD RVAELLEELG YPSIQVRGLA DSGWFLDNKQ YRRSDCIDTI NCAPTDAIRR 
       310        320        330        340        350        360 
GIRYWSGMVP ERCQRQFKEG EEWNCFFGYK VYPTLRCPVF VVQWLFDEAQ LTVDNVHLTG 
       370        380        390        400        410        420 
QPVQEGQWLY IQNLGRELRG TLKDVQASFA PACLSHEIII RSYWTDVQVK GTSLPRALHC 
       430        440        450        460        470        480 
WDRSFHDSHK ASKTPMKGCP FHLVDSCPWP HCNPSCPTIR DQFTGQEMNV AQFLMHMGFD 
       490        500    
VQTVAQQQGM EPSKLLGMLS NGN         10         20         30         40         50         60 
MGGEVRVLLL LGLLHWVGGS EGRKTWRRRG QQPPQPPPPP PLPQRAEVEP GAGQPVESFP 
        70         80         90        100        110        120 
LDFTAVEGNM DSFMAQVKSL AQSLYPCSAQ QLNEDLRLHL LLNTSVTCND GSPAGYYLKE 
       130        140        150        160        170        180 
SKGSRRWLLF LEGGWYCFNR ENCDSRYSTM RRLMSSKDWP HTRTGTGILS SQPEENPHWW 
       190        200        210        220        230        240 
NANMVFIPYC SSDVWSGASP KSDKNEYAFM GSLIIQEVVR ELLGKGLSGA KVLLLAGSSA 
       250        260        270        280        290        300 
GGTGVLLNVD RVAELLEELG YPSIQVRGLA DSGWFLDNKQ YRRSDCIDTI NCAPTDAIRR 
       310        320        330        340        350        360 
GIRYWSGMVP ERCQRQFKEG EEWNCFFGYK VYPTLRCPVF VVQWLFDEAQ LTVDNVHLTG 
       370        380        390        400        410        420 
QPVQEGQWLY IQNLGRELRG TLKDVQASFA PACLSHEIII RSYWTDVQVK GTSLPRALHC 
       430        440        450        460        470        480 
WDRSFHDSHK ASKTPMKGCP FHLVDSCPWP HCNPSCPTIR DQFTGQEMNV AQFLMHMGFD 
       490        500    
VQTVAQQQGM EPSKLLGMLS NGN



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8R116-20-unknown SEGRKT... 20 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LSNGN 503 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LSNGN 503 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78682

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)