TopFIND 4.0

Q8R3P2: Probable E3 ubiquitin-protein ligase DTX2

General Information

Protein names
- Probable E3 ubiquitin-protein ligase DTX2
- 2.3.2.27 {ECO:0000250|UniProtKB:Q61010}
- Protein deltex-2
- Deltex2
- mDTX2
- RING-type E3 ubiquitin transferase DTX2 {ECO:0000305}
Gene names Dtx2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8R3P2

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAMAPSSSLP QVYPSHVVVA VWEWQDGLGI WHPYSATVCS FIEQHFVRQR GQHFGLGSLA 
        70         80         90        100        110        120 
HSIPLGQADP SLAPYIIDLP SWTQFRQNTG TMRSVRRHLF SQNSAPGQGI VWEWLGDDGS 
       130        140        150        160        170        180 
WVAYEARICD YLEQQVARGI QVVDLAPLGY NYTVNYATLT QTNKTSSFCR SVRRQVGPVY 
       190        200        210        220        230        240 
PVTSDIAVPR QMGLICFCQQ CLHGSGTGPV SGRYRHSMTN LPAYPAPQAP HRTTTVSGAH 
       250        260        270        280        290        300 
QAFAPYNKPS LSGARSAPRL NTTNPWAAAP PVAGNQSLFH SSLSHLGPQL LPSGPSTSSG 
       310        320        330        340        350        360 
ASASFPSGPS SSSPGSAPTT VPVQMPKASR VQQALAGMTS VLSAIGLPVC LSRAPRPTGP 
       370        380        390        400        410        420 
PASRPASKSH SSVKRLRKMS VKEGAPKPEP EQVIRKYTEE LKVAPEEDCI ICMEKLAVAS 
       430        440        450        460        470        480 
GYSDMTDSKA LGPMVVGRLT KCSHAFHLLC LLAMYCNGNK DGSLQCPSCK TIYGEKTGTQ 
       490        500        510        520        530        540 
PWGKMEVFRF QMSLPGHEDC GTILIVYNIP HGIQGPEHPS PGKPFTARGF PRQCYLPDSP 
       550        560        570        580        590        600 
QGRKVLELLK VAWKRRLIFT VGTSSTTGET DTVVWNEIHH KTEMDRNVTG HGYPDPNYLQ 
       610    
NVLAELAAQG VTEDCLEQQ

Isoforms

- Isoform 2 of Probable E3 ubiquitin-protein ligase DTX2 - Isoform 3 of Probable E3 ubiquitin-protein ligase DTX2

Sequence View

        10         20         30         40         50         60 
MAMAPSSSLP QVYPSHVVVA VWEWQDGLGI WHPYSATVCS FIEQHFVRQR GQHFGLGSLA 
        70         80         90        100        110        120 
HSIPLGQADP SLAPYIIDLP SWTQFRQNTG TMRSVRRHLF SQNSAPGQGI VWEWLGDDGS 
       130        140        150        160        170        180 
WVAYEARICD YLEQQVARGI QVVDLAPLGY NYTVNYATLT QTNKTSSFCR SVRRQVGPVY 
       190        200        210        220        230        240 
PVTSDIAVPR QMGLICFCQQ CLHGSGTGPV SGRYRHSMTN LPAYPAPQAP HRTTTVSGAH 
       250        260        270        280        290        300 
QAFAPYNKPS LSGARSAPRL NTTNPWAAAP PVAGNQSLFH SSLSHLGPQL LPSGPSTSSG 
       310        320        330        340        350        360 
ASASFPSGPS SSSPGSAPTT VPVQMPKASR VQQALAGMTS VLSAIGLPVC LSRAPRPTGP 
       370        380        390        400        410        420 
PASRPASKSH SSVKRLRKMS VKEGAPKPEP EQVIRKYTEE LKVAPEEDCI ICMEKLAVAS 
       430        440        450        460        470        480 
GYSDMTDSKA LGPMVVGRLT KCSHAFHLLC LLAMYCNGNK DGSLQCPSCK TIYGEKTGTQ 
       490        500        510        520        530        540 
PWGKMEVFRF QMSLPGHEDC GTILIVYNIP HGIQGPEHPS PGKPFTARGF PRQCYLPDSP 
       550        560        570        580        590        600 
QGRKVLELLK VAWKRRLIFT VGTSSTTGET DTVVWNEIHH KTEMDRNVTG HGYPDPNYLQ 
       610    
NVLAELAAQG VTEDCLEQQ         10         20         30         40         50         60 
MAMAPSSSLP QVYPSHVVVA VWEWQDGLGI WHPYSATVCS FIEQHFVRQR GQHFGLGSLA 
        70         80         90        100        110        120 
HSIPLGQADP SLAPYIIDLP SWTQFRQNTG TMRSVRRHLF SQNSAPGQGI VWEWLGDDGS 
       130        140        150        160        170        180 
WVAYEARICD YLEQQVARGI QVVDLAPLGY NYTVNYATLT QTNKTSSFCR SVRRQVGPVY 
       190        200        210        220        230        240 
PVTSDIAVPR QMGLICFCQQ CLHGSGTGPV SGRYRHSMTN LPAYPAPQAP HRTTTVSGAH 
       250        260        270        280        290        300 
QAFAPYNKPS LSGARSAPRL NTTNPWAAAP PVAGNQSLFH SSLSHLGPQL LPSGPSTSSG 
       310        320        330        340        350        360 
ASASFPSGPS SSSPGSAPTT VPVQMPKASR VQQALAGMTS VLSAIGLPVC LSRAPRPTGP 
       370        380        390        400        410        420 
PASRPASKSH SSVKRLRKMS VKEGAPKPEP EQVIRKYTEE LKVAPEEDCI ICMEKLAVAS 
       430        440        450        460        470        480 
GYSDMTDSKA LGPMVVGRLT KCSHAFHLLC LLAMYCNGNK DGSLQCPSCK TIYGEKTGTQ 
       490        500        510        520        530        540 
PWGKMEVFRF QMSLPGHEDC GTILIVYNIP HGIQGPEHPS PGKPFTARGF PRQCYLPDSP 
       550        560        570        580        590        600 
QGRKVLELLK VAWKRRLIFT VGTSSTTGET DTVVWNEIHH KTEMDRNVTG HGYPDPNYLQ 
       610    
NVLAELAAQG VTEDCLEQQ



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8R3P2-1-unknown MAMAPS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8R3P2-1-unknown MAMAPS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73335
    Q8R3P2-1-unknown MAMAPS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73336

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CLEQQ 619 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...CLEQQ 619 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt68953

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)