TopFIND 4.0

Q8R4D1: Sodium/hydrogen exchanger 8

General Information

Protein names
- Sodium/hydrogen exchanger 8
- Na(+)/H(+) exchanger 8
- NHE-8
- Solute carrier family 9 member 8
Gene names Slc9a8
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8R4D1

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAEEEFSNTT HETFNFTLHT TLGVTTKLVL PTPAKPILPV QTGEQAQQEE QSSGMTIFFS 
        70         80         90        100        110        120 
LLVLAICIIL VHLLIRYRLH FLPESVAVVS LGILMGAVIK VIEFKKLANW KEEEMFRPNM 
       130        140        150        160        170        180 
FFLLLLPPII FESGYSLHKG NFFQNIGSIT LFAVFGTAIS AFVVGGGIYF LGQADVISKL 
       190        200        210        220        230        240 
NMTDSFAFGS LISAVDPVAT IAIFNALHVD PVLNMLVFGE SILNDAVSIV LTNTAEGLTR 
       250        260        270        280        290        300 
KHMSDVSGWQ TFSQALGYFL KMFFGSAALG TLTGLISALV LKHIDLRKTP SLEFGMMIIF 
       310        320        330        340        350        360 
AYLPYGLAEG ISLSGIMAIL FSGIVMSHYT HHNLSPVTQI LMQQTLRTVA FLCETCVFAF 
       370        380        390        400        410        420 
LGLSIFSFPH KFEISFVIWC IVLVLFGRAV NIFPLSYLLN FFRDHKITPK MMFIMWFSGL 
       430        440        450        460        470        480 
RGAIPYALSL HLGLEPMEKR QLIGTTTIVI VLFTILLLGG STMPLIRLVD IEDARARRRS 
       490        500        510        520        530        540 
KKDVNLSKTE KMGNAIESEH LSELTEEEYE AHYIRQQDLK GFMWLDAKYL NPFFTRRLTQ 
       550        560        570    
EDLHHGRIQM KSLTNKWYEE VRQGPSGSED DEQELF

Isoforms

- Isoform 2 of Sodium/hydrogen exchanger 8 - Isoform 3 of Sodium/hydrogen exchanger 8

Sequence View

        10         20         30         40         50         60 
MAEEEFSNTT HETFNFTLHT TLGVTTKLVL PTPAKPILPV QTGEQAQQEE QSSGMTIFFS 
        70         80         90        100        110        120 
LLVLAICIIL VHLLIRYRLH FLPESVAVVS LGILMGAVIK VIEFKKLANW KEEEMFRPNM 
       130        140        150        160        170        180 
FFLLLLPPII FESGYSLHKG NFFQNIGSIT LFAVFGTAIS AFVVGGGIYF LGQADVISKL 
       190        200        210        220        230        240 
NMTDSFAFGS LISAVDPVAT IAIFNALHVD PVLNMLVFGE SILNDAVSIV LTNTAEGLTR 
       250        260        270        280        290        300 
KHMSDVSGWQ TFSQALGYFL KMFFGSAALG TLTGLISALV LKHIDLRKTP SLEFGMMIIF 
       310        320        330        340        350        360 
AYLPYGLAEG ISLSGIMAIL FSGIVMSHYT HHNLSPVTQI LMQQTLRTVA FLCETCVFAF 
       370        380        390        400        410        420 
LGLSIFSFPH KFEISFVIWC IVLVLFGRAV NIFPLSYLLN FFRDHKITPK MMFIMWFSGL 
       430        440        450        460        470        480 
RGAIPYALSL HLGLEPMEKR QLIGTTTIVI VLFTILLLGG STMPLIRLVD IEDARARRRS 
       490        500        510        520        530        540 
KKDVNLSKTE KMGNAIESEH LSELTEEEYE AHYIRQQDLK GFMWLDAKYL NPFFTRRLTQ 
       550        560        570    
EDLHHGRIQM KSLTNKWYEE VRQGPSGSED DEQELF         10         20         30         40         50         60 
MAEEEFSNTT HETFNFTLHT TLGVTTKLVL PTPAKPILPV QTGEQAQQEE QSSGMTIFFS 
        70         80         90        100        110        120 
LLVLAICIIL VHLLIRYRLH FLPESVAVVS LGILMGAVIK VIEFKKLANW KEEEMFRPNM 
       130        140        150        160        170        180 
FFLLLLPPII FESGYSLHKG NFFQNIGSIT LFAVFGTAIS AFVVGGGIYF LGQADVISKL 
       190        200        210        220        230        240 
NMTDSFAFGS LISAVDPVAT IAIFNALHVD PVLNMLVFGE SILNDAVSIV LTNTAEGLTR 
       250        260        270        280        290        300 
KHMSDVSGWQ TFSQALGYFL KMFFGSAALG TLTGLISALV LKHIDLRKTP SLEFGMMIIF 
       310        320        330        340        350        360 
AYLPYGLAEG ISLSGIMAIL FSGIVMSHYT HHNLSPVTQI LMQQTLRTVA FLCETCVFAF 
       370        380        390        400        410        420 
LGLSIFSFPH KFEISFVIWC IVLVLFGRAV NIFPLSYLLN FFRDHKITPK MMFIMWFSGL 
       430        440        450        460        470        480 
RGAIPYALSL HLGLEPMEKR QLIGTTTIVI VLFTILLLGG STMPLIRLVD IEDARARRRS 
       490        500        510        520        530        540 
KKDVNLSKTE KMGNAIESEH LSELTEEEYE AHYIRQQDLK GFMWLDAKYL NPFFTRRLTQ 
       550        560        570    
EDLHHGRIQM KSLTNKWYEE VRQGPSGSED DEQELF



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8R4D1-1-unknown MAEEEF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8R4D1-1-unknown MAEEEF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89884

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)